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Understandings, attitudes, practices and responses to GHB overdose among GHB consumers
BackgroundGamma-hydroxybutyrate (GHB) is used at disproportionately high rates within sexuality and gender diverse communities and carries a high...
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GHB: a life-threatening drug complications and outcome of GHB detoxification treatment—an observational clinical study
BackgroundGHB (gammahydroxybutyrate) and its precursors are popular recreational drugs due to their sedative, anxiolytic and sexually stimulating...
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Pharmacological Treatment of GHB Withdrawal Syndrome
Purpose of ReviewGamma-hydroxybutyrate (GHB) is an illicit drug used for many reasons: during music festivals or parties, for self-management of...
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Predicting the Number of GHB-Related Toxicologic Admissions Using Google Trends Data
In the era of novel psychoactive substances (NPS), the internet became a relevant source of information and purchase for those who consume...
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Tapering with Pharmaceutical GHB or Benzodiazepines for Detoxification in GHB-Dependent Patients: A Matched-Subject Observational Study of Treatment-as-Usual in Belgium and The Netherlands
BackgroundThe gamma-hydroxybutyric acid (GHB) withdrawal syndrome often has a fulminant course, with a rapid onset and swift progression of severe...
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The challenge of post-mortem GHB analysis: storage conditions and specimen types are both important
BackgroundFor the interpretation of concentrations of gamma-hydroxybutyrate (GHB) in post-mortem specimens, a possible increase due to post-mortem...
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Diagnostic accuracy and clinical usefulness of erythrocyte creatine content to predict the improvement of anaemia in patients receiving maintenance haemodialysis
BackgroundThe improvement of anaemia over time by erythropoiesis stimulating agent (ESA) is associated with better survival in haemodialysis...
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Chemsex Practices in PrEP: Beyond Addiction and Risk Toward a Healthy Sex Life—Baseline Experiences from a Hospital-Based PrEP Program in Barcelona, Spain
Pre-exposure prophylaxis (PrEP) is a biomedical intervention that has demonstrated efficacy in HIV prevention in individuals at high-risk, among them...
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Chemsex: review of the current literature and treatment guidelines
Purposeof the reviewChemsex mainly concerned men who have sex with men, but seems to spread in general population. Clinical characteristics and...
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Interaction of sleep duration and depression on cardiovascular disease: a retrospective cohort study
BackgroundTo assess the interaction of sleep duration and depression on the risk of cardiovascular disease (CVD).
MethodsA total of 13,488 eligible...
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Patterns of Event-Level Concurrent Substance Use During Sex Among Gay, Bisexual, and Other Men Who Have Sex with Men in Metro Vancouver
This study identified patterns of sexualized substance use among gay, bisexual, and other men who have sex with men (gbMSM) and examined associated...
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Tobacco, alcohol, cannabis, and illicit drug use and their association with CD4/CD8 cell count ratio in people with controlled HIV: a cross-sectional study (ANRS CO3 AQUIVIH-NA-QuAliV)
BackgroundTo evaluate drug use (alcohol, tobacco, cannabis and other drugs) and its association with mean CD4/CD8 T cell count ratio, a marker of...
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Do ART and Chemsex Drugs Get Along? Potential Drug–Drug Interactions in a Cohort of People Living with HIV Who Engaged in Chemsex: A Retrospective Observational Study
IntroductionPeople living with HIV (PLWH) who engaged in chemsex are at risk of potential drug–drug interactions (pDDIs) with recreational drugs....
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Which interventions for alcohol use should be included in a universal healthcare benefit package? An umbrella review of targeted interventions to address harmful drinking and dependence
BackgroundThis study aimed to identify targeted interventions for the prevention and treatment of harmful alcohol use. Umbrella review methodology...
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Association of cholinesterase activities and POD in older adult abdominal surgical patients
BackgroundPostoperative delirium (POD) is a frequent complication after surgery. Older adult patients undergoing abdominal surgery are at higher risk...
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Epidemiological shift of glucose-6-phosphate dehydrogenase mutations in northern Italy in the last 15 years
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked recessive hemolytic anemia caused by mutations in G6PD gene. The distribution and...
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Increasing emergency department admissions for chemsex-related intoxications in Barcelona, Spain, among people living with HIV: an observational study from 2018 to 2020
BackgroundChemsex is a novel phenomenon referring to the use of drugs, including crystal methamphetamine, gammahydroxybutyric acid...