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Application of comprehensive unit-based safety program model to improve chemotherapy-induced nausea and vomiting in patients with ovarian cancer: a retrospective study
BackgroundTo explore the effect of intervention programs constructed under the guidance of the comprehensive unit-based safety program (CUSP) model...
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Effects of different auricular point therapies on digestive symptoms and quality of life in patients undergoing platinum-based chemotherapy
ObjectiveTo compare the effects of auricular point intradermal needling with auricular point sticking on digestive symptoms and quality of life in...
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Characteristics of nausea and its impact on health-related quality of life in cisplatin-treated patients receiving dexamethasone-sparing prophylaxis: an analysis of the LUNG-NEPA study
PurposeWe investigated the intensity and duration of nausea as well as its impact on health-related quality of life among cisplatin-treated patients...
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Olanzapine (5 mg) plus standard triple antiemetic therapy for the prevention of multiple-day cisplatin hemotherapy-induced nausea and vomiting: a prospective randomized controlled study
ObjectiveA prospective randomized controlled trial was conducted to compare 5 mg olanzapine plus standard triple antiemetic therapy for the...
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The efficacy of aprepitant in salvage treatment of chemotherapy-induced nausea and vomiting associated with moderately emetogenic chemotherapy for patients with gastrointestinal cancer
PurposeTo evaluate the efficacy of aprepitant and its effect on the quality of life when added to standard antiemetic therapy as salvage therapy.
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Impact of fosaprepitant in the prevention of nausea and emesis in head and neck cancer patients undergoing cisplatin-based chemoradiation: a pilot prospective study and a review of literature
PurposeCisplatin-based chemoradiotherapy (CRT) is standard treatment for head and neck squamous cell carcinoma (HNSCC). However, IMRT may increase...
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Comprehensive geriatric assessment predicts radiation-induced acute toxicity in prostate cancer patients
PurposeThe purpose of the present prospective study was to evaluate the significance of geriatric conditions measured by a comprehensive geriatric...
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Two doses of fosaprepitant included prophylactic treatment for the three-day cisplatin-based chemotherapy induced nausea and vomiting
PurposeNeurokinin 1 receptor antagonists included prophylactic treatment was recommended for patients who receive one-day cisplatin chemotherapy. It...
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Quality of life issues in patients with bone metastases: A systematic review
IntroductionBones are frequent sites of metastatic disease, observed in 30–75% of advanced cancer patients. Quality of life (QoL) is an important...
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Mirtazapine, a dopamine receptor inhibitor, as a secondary prophylactic for delayed nausea and vomiting following highly emetogenic chemotherapy: an open label, randomized, multicenter phase III trial
Background We examined the efficacy of mirtazapine in preventing delayed nausea and vomiting following highly emetogenic chemotherapy (HEC). Patients...
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Cost-effectiveness analysis of NEPA, a fixed-dose combination of netupitant and palonosetron, for the prevention of highly emetogenic chemotherapy-induced nausea and vomiting: an international perspective
PurposeThe aim of this study was to assess the cost-effectiveness of NEPA, a fixed-dose combination of oral netupitant (300 mg) and palonosetron...
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Antiemetic prophylaxis for chemoradiotherapy-induced nausea and vomiting in locally advanced head and neck squamous cell carcinoma: a prospective phase II trial
BackgroundThere is sparse research reporting effective interventions for preventing nausea and emesis caused by concurrent chemoradiotherapy (CCRT)...
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Multinational Association of Supportive Care in Cancer (MASCC) expert opinion/consensus guidance on the use of cannabinoids for gastrointestinal symptoms in patients with cancer
BackgroundGastrointestinal symptoms are common in patients with cancer, whether related to treatment or a direct effect of the disease itself....
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Paediatric hydrocephalus
Hydrocephalus is classically considered as a failure of cerebrospinal fluid (CSF) homeostasis that results in the active expansion of the cerebral...
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Luminal Gastrointestinal Manifestations of Cystic Fibrosis
Purpose of ReviewPeople with cystic fibrosis (CF) are living longer. General age-related and CF-specific gastrointestinal symptoms are increasingly...
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A Tailored Approach to Laparoscopic Fundoplication: Outcomes in Patients with Esophageal Dysmotility
BackgroundEsophageal dysmotility is a common finding in patients being evaluated for antireflux surgery, although its implication remains unclear. We...
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A prospective randomized controlled clinical trial investigating the efficacy of low-dose olanzapine in preventing nausea and vomiting associated with oxaliplatin-based and irinotecan-based chemotherapy
ObjectiveThe aim of this study is to assess the clinical efficacy of a 5 mg dosage of olanzapine in preventing chemotherapy-induced nausea and...
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Significant changes in impedance planimetry (EndoFLIP™) measurements after peroral pyloromyotomy for delayed gastric emptying
BackgroundThe endoluminal functional lumen imaging probe (FLIP) can be used to obtain real-time measurements of the diameter ( D min ), cross-sectional...
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Cost-effectiveness analysis of olanzapine-containing antiemetic therapy for the prophylaxis of chemotherapy-induced nausea and vomiting (CINV) in highly emetogenic chemotherapy (HEC) patients
PurposeOlanzapine-containing regimens have been reported to be effective in preventing CINV following highly emetogenic chemotherapy (HEC), but it is...
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Systematic review of health-related quality of life (HRQoL) issues associated with gastric cancer: capturing cross-cultural differences
The treatment landscape for gastric cancer (GC) is constantly evolving with therapies affecting all aspects of health-related quality of life (HRQoL)...
