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A safety evaluation of allogeneic freeze-dried platelet-rich plasma or conditioned serum compared to autologous frozen products equivalents in equine healthy joints
BackgroundHemoderivatives such as autologous conditioned serum (ACS) and platelet-rich plasma (PRP) have been used as potential disease-modifying...
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Lyophilized (freeze-dried) human milk for preterm infants: a sco** review
Freeze-drying (FD), or lyophilization, is commonly used to preserve foods. FD offers potential to create a human milk-derived human milk fortifier,...
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The impact of fresh versus frozen-thawed embryos on maternal serum analyte levels in IVF singleton and twin pregnancies
PurposeTo determine whether embryo cryopreservation is associated with a difference in maternal serum analyte levels in singleton and twin...
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Process development and quality attributes for the freeze-drying process in pharmaceuticals, biopharmaceuticals and nanomedicine delivery: a state-of-the-art review
BackgroundProcess intensification is a major hurdle in pharmaceutical process scale-up. Solvent removal strategies have limited the effectiveness of...
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Freeze-thawing impairs the motility, plasma membrane integrity and mitochondria function of boar spermatozoa through generating excessive ROS
BackgroundCryopreservation is an efficient way to store spermatozoa and is closely associated with the quality of sperm after the freeze-thaw...
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Laboratory evaluation of a new integrative assay to phenotype plasma fibrinolytic system
BackgroundThere is currently no universal and standardized test available to phenotype plasma fibrinolytic system.
AimsOur main aims were to...
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Comparison of Clinical and Radiographic Assessment of Efficacy of Eggshell-Derived Nanohydroxyapatite (EnHA) and Demineralized Freeze-Dried Bone Allograft (DFDBA), Both Covered with Platelet-Rich Fibrin (PRF) as a Barrier Membrane in Socket Preservation: A Randomized Controlled Clinical Trial
BackgroundBone grafting has been employed for many years to assist with bone repair. Many forms of bone graft are available which differ in their...
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Cryopreserved versus fresh peripheral blood allogeneic stem cell transplantation outcomes in patients receiving post-transplant cyclophosphamide for graft-versus-host prophylaxis during the COVID-19 pandemic: a single center experience
Background/objectiveCryopreservation of grafts is not common practice in allogeneic hematopoietic stem cell transplant (HSCT) recipients. However,...
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A simple method for the determination of acyclovir concentrations in human plasma using high-performance liquid chromatography
BackgroundAcyclovir is an anti-viral medication given to treat herpes simplex and herpes zoster infection. In some severe conditions such as herpes...
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Is Fresh Frozen Plasma Still Necessary for Management of Acute Traumatic Coagulopathy?
Purpose of ReviewMassive blood loss secondary to major trauma is a leading cause of death worldwide. In recent years, multiple different strategies...
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Bioanalytical method development and validation for the simultaneous estimation of Olanzapine and Samidorphan in rabbit plasma by using HPLC–MS/MS and application to pharmacokinetic study
BackgroundSamidorphan is an opioid antagonist while Olanzapine is an effective medication for schizophrenia and bipolar disorder. A unique and...
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Macro- and microelements in serum and seminal plasma as biomarkers for bull sperm cryotolerance
BackgroundWide variation in fertility rates is observed when using frozen bull semen, even when the bulls have met quality standards for semen...
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Effects of hawthorn seed oil on plasma cholesterol and gut microbiota
BackgroundHypercholesterolemia and gut microbiota dysbiosis are associated with the risk of cardiovascular diseases. Hawthorn fruits has shown to be...
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The efficacy and safety of pre-hospital plasma in patients at risk for hemorrhagic shock: an updated systematic review and meta-analysis of randomized controlled trials
Background and objectivePlasma is a critical element in hemostatic resuscitation post-injury, and its prompt administration within the prehospital...
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Alterations of the peptidomic composition of peripheral plasma after portal hypertension correction by transjugular intrahepatic portosystemic shunt
Portal hypertension develops in patients with advanced chronic liver diseases (CLD), especially cirrhosis and is associated with complications, such...
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The serum oestradiol/progesterone ratio on the day of OPU + 7, but not the day of OPU + 5, affects the rates of live birth in fresh blastocyst embryo transfer cycles
BackgroundIn an in vitro fertilization (IVF) cycle, the embryo ends its wandering time and begins the process of implantation into the uterine cavity...
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Effects of therapeutic plasma exchange on the endothelial glycocalyx in septic shock
BackgroundDisruption of the endothelial glycocalyx (eGC) is observed in septic patients and its injury is associated with multiple-organ failure and...
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Aspiration with Diosmin Intake in Endometrial Cavity Fluid Accumulation in ART Cycles: A Randomized Controlled Trial
BackgroundThis was a prospective randomized controlled trial in 200 cases presented with endometrial cavity fluid at the day of oocyte retrieval at a...
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Individual immune cell and cytokine profiles determine platelet-rich plasma composition
ObjectivePlatelet-rich plasma (PRP) therapy is increasingly popular to treat musculoskeletal diseases, including tendinopathies and osteoarthritis...
