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Fracture-related infection
Musculoskeletal trauma leading to broken and damaged bones and soft tissues can be a life-threating event. Modern orthopaedic trauma surgery,...
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Costs of fracture-related infection: the impact on direct hospital costs and healthcare utilisation
PurposeFracture-Related Infection (FRI) is associated with high medical costs and prolonged healthcare utilization. However, limited data is...
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Key aspects of soft tissue management in fracture-related infection: recommendations from an international expert group
A judicious, well-planned bone and soft tissue debridement remains one of the cornerstones of state-of-the-art treatment of fracture-related...
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Comparative analysis of pathogen distribution in patients with fracture-related infection and periprosthetic joint infection: a retrospective study
BackgroundThe purpose of this study is to investigate the microbial patterns of periprosthetic joint infection (PJI) and fracture-related infection...
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Complications associated with single-level bone transport for the treatment of tibial bone defects caused by fracture-related infection
BackgroundThe purpose of this study was to report the outcomes of single-level bone transport with a unilateral external fixator for treatment of...
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Which non-infection related risk factors are associated with impaired proximal femur fracture healing in patients under the age of 70 years?
Background/purposeImpaired healing is a feared complication with devastating outcomes for each patient. Most studies focus on geriatric fracture...
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Fracture related infection (FRI) of the upper extremity correlates with poor bone and soft tissue healing
PurposeThe purpose of this study was to evaluate the specific course and complication profile following the development of FRI in the upper extremity.
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Analyzing risk factors for treatment failure in fracture-related infection
IntroductionFracture-related infection (FRI) represents a challenging clinical scenario. Limited evidence exists regarding treatment failure after...
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Intramedullary application of local antibiotic bullets for the treatment of long bone fracture related infection
PurposeThe optimal means of local antibiotic delivery for fracture related infection is unknown. Until now, intramedullary application of calcium...
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Compassionate use of cefiderocol in a complex case of extensively drug-resistant Acinetobacter baumannii fracture-related infection: a comprehensive approach and multidisciplinary management
PurposeFracture-related infections (FRI) pose a difficult management problem, as they require numerous surgical interventions and extended antibiotic...
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Type of antibiotic but not the duration of prophylaxis correlates with rates of fracture-related infection
PurposeThe issue of optimal prophylactic antibiotic administration for closed and open fracture surgeries remains controversial. The purpose of this...
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Bifocal versus trifocal bone transport for the management of tibial bone defects caused by fracture-related infection: a meta-analysis
BackgroundThe purpose of this meta-analysis was to compare the efficacy and outcomes of bifocal bone transport (BFT) and trifocal bone transport...
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Prior use of antibiotics and immunosuppression are risk factors for fracture-related infection during the COVID-19 pandemic period: a Brazilian prospective cohort study
BackgroundLittle is known about the role of COVID-19 pandemic period on the epidemiology of fracture-related infection (FRI). The present study...
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Epidemiology and microbiology of fracture-related infection: a multicenter study in Northeast China
ObjectiveThis study aimed to explore the epidemiological and microbiological characteristics of fracture-related infection (FRI), analyze the drug...
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Three-stage limb salvage in tibial fracture related infection with composite bone and soft-tissue defect
IntroductionManaging critical-sized tibial defects is one of the most complex challenges orthopedic surgeons face. This is even more problematic in...
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Current concepts in the prevention, diagnosis and treatment of fracture-related infection (FRI)
Fracture-related infection (FRI) is one of the most challenging complications following operative management of fractures. It can have profound...
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Potential of Continuous Local Antibiotic Perfusion Therapy for Fracture-Related Infections
IntroductionFracture-related infections (FRIs) are challenging for orthopedic surgeons, as conventional surgical treatment and systemic antimicrobial...
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A fluorogenic micrococcal nuclease-based probe for fast detection and optical imaging of Staphylococcus aureus in prosthetic joint and fracture-related infections
PurposeStaphylococcus aureus is the most common and impactful multi-drug resistant pathogen implicated in (periprosthetic) joint infections (PJI)...
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Bacteria-targeted fluorescence imaging of extracted osteosynthesis devices for rapid visualization of fracture-related infections
PurposeFracture-related infection (FRI) is a serious complication in orthopedic trauma surgery worldwide. Especially, the distinction of infection...