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  1. Fracture-related infection

    Musculoskeletal trauma leading to broken and damaged bones and soft tissues can be a life-threating event. Modern orthopaedic trauma surgery,...

    T. Fintan Moriarty, Willem-Jan Metsemakers, ... R. Geoff Richards in Nature Reviews Disease Primers
    Article 20 October 2022
  2. Costs of fracture-related infection: the impact on direct hospital costs and healthcare utilisation

    Purpose

    Fracture-Related Infection (FRI) is associated with high medical costs and prolonged healthcare utilization. However, limited data is...

    S. Haidari, M.A.S. Buijs, ... G.A.M. Govaert in European Journal of Trauma and Emergency Surgery
    Article Open access 09 April 2024
  3. Key aspects of soft tissue management in fracture-related infection: recommendations from an international expert group

    A judicious, well-planned bone and soft tissue debridement remains one of the cornerstones of state-of-the-art treatment of fracture-related...

    Leonard C. Marais, Sven Hungerer, ... Werner Zimmerli in Archives of Orthopaedic and Trauma Surgery
    Article Open access 03 November 2023
  4. Comparative analysis of pathogen distribution in patients with fracture-related infection and periprosthetic joint infection: a retrospective study

    Background

    The purpose of this study is to investigate the microbial patterns of periprosthetic joint infection (PJI) and fracture-related infection...

    Tiancong Ma, **yang Lyu, ... Gangyong Huang in BMC Musculoskeletal Disorders
    Article Open access 13 February 2023
  5. Complications associated with single-level bone transport for the treatment of tibial bone defects caused by fracture-related infection

    Background

    The purpose of this study was to report the outcomes of single-level bone transport with a unilateral external fixator for treatment of...

    Kai Liu, Qiyu Jia, ... Aihemaitijiang Yusufu in BMC Musculoskeletal Disorders
    Article Open access 23 June 2023
  6. Which non-infection related risk factors are associated with impaired proximal femur fracture healing in patients under the age of 70 years?

    Background/purpose

    Impaired healing is a feared complication with devastating outcomes for each patient. Most studies focus on geriatric fracture...

    Sascha Halvachizadeh, David Paul Martin, ... Till Berk in BMC Musculoskeletal Disorders
    Article Open access 20 May 2023
  7. Fracture related infection (FRI) of the upper extremity correlates with poor bone and soft tissue healing

    Purpose

    The purpose of this study was to evaluate the specific course and complication profile following the development of FRI in the upper extremity.

    ...
    Lauren A. Merrell, Jack C. Adams, ... Kenneth A. Egol in European Journal of Orthopaedic Surgery & Traumatology
    Article 27 November 2023
  8. Analyzing risk factors for treatment failure in fracture-related infection

    Introduction

    Fracture-related infection (FRI) represents a challenging clinical scenario. Limited evidence exists regarding treatment failure after...

    Taylor M. Yong, Forrest A. Rackard, ... Ida L. Gitajn in Archives of Orthopaedic and Trauma Surgery
    Article 19 January 2022
  9. Intramedullary application of local antibiotic bullets for the treatment of long bone fracture related infection

    Purpose

    The optimal means of local antibiotic delivery for fracture related infection is unknown. Until now, intramedullary application of calcium...

    Preemal Patel, Alexis-Dimitris Iliadis, ... Alex Trompeter in European Journal of Orthopaedic Surgery & Traumatology
    Article 13 January 2022
  10. Compassionate use of cefiderocol in a complex case of extensively drug-resistant Acinetobacter baumannii fracture-related infection: a comprehensive approach and multidisciplinary management

    Purpose

    Fracture-related infections (FRI) pose a difficult management problem, as they require numerous surgical interventions and extended antibiotic...

    Flavia Petrucci, Beatrice Perciballi, ... Daniele De Meo in Infection
    Article Open access 15 May 2024
  11. Type of antibiotic but not the duration of prophylaxis correlates with rates of fracture-related infection

    Purpose

    The issue of optimal prophylactic antibiotic administration for closed and open fracture surgeries remains controversial. The purpose of this...

    Stefânia Prebianchi, Eduardo Cezar Santos, ... Mauro José Salles in European Journal of Orthopaedic Surgery & Traumatology
    Article 09 March 2022
  12. Bifocal versus trifocal bone transport for the management of tibial bone defects caused by fracture-related infection: a meta-analysis

    Background

    The purpose of this meta-analysis was to compare the efficacy and outcomes of bifocal bone transport (BFT) and trifocal bone transport...

    Kai Liu, Hongyan Zhang, ... Aihemaitijiang Yusufu in Journal of Orthopaedic Surgery and Research
    Article Open access 25 February 2023
  13. Prior use of antibiotics and immunosuppression are risk factors for fracture-related infection during the COVID-19 pandemic period: a Brazilian prospective cohort study

    Background

    Little is known about the role of COVID-19 pandemic period on the epidemiology of fracture-related infection (FRI). The present study...

    Eduardo Cezar Santos, Stefânia Prebianchi, ... Mauro José Salles in BMC Musculoskeletal Disorders
    Article Open access 04 June 2022
  14. Epidemiology and microbiology of fracture-related infection: a multicenter study in Northeast China

    Objective

    This study aimed to explore the epidemiological and microbiological characteristics of fracture-related infection (FRI), analyze the drug...

    Baisheng Wang, **aoguang **ao, ... **n Tang in Journal of Orthopaedic Surgery and Research
    Article Open access 12 August 2021
  15. Three-stage limb salvage in tibial fracture related infection with composite bone and soft-tissue defect

    Introduction

    Managing critical-sized tibial defects is one of the most complex challenges orthopedic surgeons face. This is even more problematic in...

    Pablo S. Corona, Carla Carbonell-Rosell, ... Vaida Glatt in Archives of Orthopaedic and Trauma Surgery
    Article Open access 22 December 2021
  16. Current concepts in the prevention, diagnosis and treatment of fracture-related infection (FRI)

    Fracture-related infection (FRI) is one of the most challenging complications following operative management of fractures. It can have profound...

    Alexios Dimitrios Iliadis, Faiz Shivji, ... Nima Heidari in European Journal of Orthopaedic Surgery & Traumatology
    Article 29 March 2021
  17. Potential of Continuous Local Antibiotic Perfusion Therapy for Fracture-Related Infections

    Introduction

    Fracture-related infections (FRIs) are challenging for orthopedic surgeons, as conventional surgical treatment and systemic antimicrobial...

    Kenji Kosugi, Yukichi Zenke, ... Akinori Sakai in Infectious Diseases and Therapy
    Article Open access 21 May 2022
  18. A fluorogenic micrococcal nuclease-based probe for fast detection and optical imaging of Staphylococcus aureus in prosthetic joint and fracture-related infections

    Purpose

    Staphylococcus aureus is the most common and impactful multi-drug resistant pathogen implicated in (periprosthetic) joint infections (PJI)...

    Jorrit W.A. Schoenmakers, Marina López‑Álvarez, ... Jan Maarten van Dijl in European Journal of Nuclear Medicine and Molecular Imaging
    Article Open access 14 November 2023
  19. Bacteria-targeted fluorescence imaging of extracted osteosynthesis devices for rapid visualization of fracture-related infections

    Purpose

    Fracture-related infection (FRI) is a serious complication in orthopedic trauma surgery worldwide. Especially, the distinction of infection...

    Marina López-Álvarez, Marjolein Heuker, ... Marleen van Oosten in European Journal of Nuclear Medicine and Molecular Imaging
    Article Open access 26 January 2022
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