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  1. Folate and retinal vascular diseases

    Folate, a pteroylglutamic acid derivative, participates in fundamental cellular metabolism. Homocysteine, an amino acid, serves as an intermediate of...

    **yue Gu, Chunyan Lei, Meixia Zhang in BMC Ophthalmology
    Article Open access 13 October 2023
  2. Construction and validation of a folate metabolism-related gene signature for predicting prognosis in HNSCC

    Purpose

    Metabolic reprogramming is currently considered a hallmark of tumor and immune development. It is obviously of interest to identify metabolic...

    Lu Wang, Ye He, ... Xuewen Wu in Journal of Cancer Research and Clinical Oncology
    Article Open access 16 April 2024
  3. Negative associations between folate and bacterial vaginosis in the NHANES 2001 to 2004

    Background

    Bacterial vaginosis (BV) is one of the most common infections among women of reproductive age and accounts for 15–50% of infections...

    Ting-Ting Cui, **g Luo, ... Xu-Guang Guo in BMC Infectious Diseases
    Article Open access 19 July 2023
  4. Association between dietary folate intake and the risk of osteoporosis in adults: a cross-sectional study

    Background

    Increased intake of specific vitamins has been linked to a decreased prevalence of osteoporosis. However, the association between dietary...

    Li Zhou, Weinmin Deng, ... Hongxing Huang in BMC Musculoskeletal Disorders
    Article Open access 22 June 2024
  5. Folate deficiency may increase the risk for elevated TSH in patients with type 2 diabetes mellitus

    Background

    Type 2 diabetes mellitus (T2DM) and thyroid dysfunction (TD) are two common chronic endocrine disorders that often coexist. Folate...

    Lin Lin, Yushan Du, ... Jufen Liu in BMC Endocrine Disorders
    Article Open access 11 August 2023
  6. Association between dietary folate intake and bone mineral density in a diverse population: a cross-sectional study

    Background

    Osteoporosis is a major public health problem, yet the association between dietary folate intake and bone health has been rarely studied....

    Zitian Zheng, Huanhuan Luo, ... Qingyun Xue in Journal of Orthopaedic Surgery and Research
    Article Open access 14 September 2023
  7. Folate, vitamin B12 and vitamin D status in healthy and active home-dwelling people over 70 years

    Background

    Ageing is characterised by physiological changes that can affect the nutrient availability and requirements. In particular, the status of...

    Felix Kerlikowsky, Jan Philipp Schuchardt, Andreas Hahn in BMC Geriatrics
    Article Open access 18 October 2023
  8. Human milk oligosaccharide composition following supplementation with folic acid vs (6S)-5-methyltetrahydrofolic acid during pregnancy and mediation by human milk folate forms

    Supplementation with folic acid versus (6 S )-5-methyltetrahydrofolic acid (5-MTHF) results in different folate forms in human milk, with folic acid...

    Kelsey M. Cochrane, Jeffrey N. Bone, ... Lars Bode in European Journal of Clinical Nutrition
    Article Open access 06 December 2023
  9. Challenges in Pharmacokinetic Modelling of [18F]fluoro-PEG-folate PET/CT Imaging in Epithelial Ovarian Cancer Patients

    Purpose

    To describe the pharmacokinetic properties of the [ 18 F]fluoro-polyethylene glycol(PEG)-folate radiotracer in PET/CT imaging of patients with...

    Thomas Ruytenberg, Isabeau A. Ciggaar, ... Lioe-Fee de Geus-Oei in Molecular Imaging and Biology
    Article Open access 22 May 2024
  10. Non-linear associations of serum and red blood cell folate with risk of cardiovascular and all-cause mortality in hypertensive adults

    This study aims to assess the associations of serum and red blood cell (RBC) folate with cardiovascular and all-cause mortality in hypertensive...

    **g Xu, Xu Zhu, ... Ling Zhu in Hypertension Research
    Article 10 March 2023
  11. Association between red blood cell folate and Trichomonas vaginalis infection among women

    Background

    Increased folic acid has been found to be latently protective against gynecological infection, including several kinds of vaginosis. In...

    Wan-Zhe Liao, Zhi-Yi Zhou, ... Xu-Guang Guo in BMC Infectious Diseases
    Article Open access 23 January 2023
  12. Dose-response association between dietary folate and niacin intakes with diabetes among Chinese adults: a cross-sectional study

    Background

    The aim of this study was to examine the relationship between dietary intake of folate and niacin and diabetes risk in Chinese adults.

    ...
    Yuhong Jiang, Zhiwen Zhang, ... Hong **e in Journal of Health, Population and Nutrition
    Article Open access 10 April 2023
  13. Co-occurrence of iron, folate, and vitamin A deficiency among pregnant women in eastern Ethiopia: a community-based study

    Background

    It is well known that the magnitude of undernutrition in Ethiopia is unacceptably high. The burden of co-occurrence of iron, folate, and...

    Meseret Belete Fite, Abera Kenay Tura, ... Kedir Teji Roba in BMC Nutrition
    Article Open access 23 June 2023
  14. Vitamin C and folate status in hereditary fructose intolerance

    Background

    Hereditary fructose intolerance (HFI) is a rare inborn error of fructose metabolism caused by the deficiency of aldolase B. Since treatment...

    Ainara Cano, Carlos Alcalde, ... Javier de las Heras in European Journal of Clinical Nutrition
    Article Open access 19 July 2022
  15. Predicting the effect of different folate doses on [68Ga]Ga-PSMA-11 organ and tumor uptake using physiologically based pharmacokinetic modeling

    Background

    Folate intake might reduce [ 68 Ga]Ga-PSMA-11 uptake in tissues due to a competitive binding to the PSMA receptor. For diagnostic imaging,...

    Hinke Siebinga, Jeroen J. M. A. Hendrikx, ... Berlinda J. de Wit-van der Veen in EJNMMI Research
    Article Open access 15 June 2023
  16. Dietary folate drives methionine metabolism to promote cancer development by stabilizing MAT IIA

    Folic acid, served as dietary supplement, is closely linked to one-carbon metabolism and methionine metabolism. Previous clinical evidence indicated...

    **-Tao Li, Hai Yang, ... Qun-Ying Lei in Signal Transduction and Targeted Therapy
    Article Open access 22 June 2022
  17. Prenatal exposure to tobacco and adverse birth outcomes: effect modification by folate intake during pregnancy

    Background

    Fetal exposure to tobacco increases the risk for many adverse birth outcomes, but whether diet mitigates these risks has yet to be...

    Adrienne T. Hoyt, Anna V. Wilkinson, ... Brianna F. Moore in Maternal Health, Neonatology and Perinatology
    Article Open access 12 September 2022
  18. An infantile case of hereditary folate malabsorption with sudden development of pulmonary hemorrhage: a case report

    Background

    Hereditary folate malabsorption—a rare disorder caused by impairment of the folate transporter—can develop into severe folate deficiency...

    Yukari Sakurai, Naohisa Toriumi, ... Hiroshi Azuma in Journal of Medical Case Reports
    Article Open access 30 June 2022
  19. Global strategies for the prevention of neural tube defects through the improvement of folate status in women of reproductive age

    Introduction

    Neural tube defects represent a global public health problem, mainly in countries where effective prevention strategies are not yet in...

    Homero Martinez, Adriana Benavides-Lara, ... Alexander Arynchyn in Child's Nervous System
    Article 27 April 2023
  20. Folate and cardiovascular disease

    Yu Otsu, Ryusuke Ae, Masanari Kuwabara in Hypertension Research
    Article 12 May 2023
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