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Folate and retinal vascular diseases
Folate, a pteroylglutamic acid derivative, participates in fundamental cellular metabolism. Homocysteine, an amino acid, serves as an intermediate of...
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Construction and validation of a folate metabolism-related gene signature for predicting prognosis in HNSCC
PurposeMetabolic reprogramming is currently considered a hallmark of tumor and immune development. It is obviously of interest to identify metabolic...
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Negative associations between folate and bacterial vaginosis in the NHANES 2001 to 2004
BackgroundBacterial vaginosis (BV) is one of the most common infections among women of reproductive age and accounts for 15–50% of infections...
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Association between dietary folate intake and the risk of osteoporosis in adults: a cross-sectional study
BackgroundIncreased intake of specific vitamins has been linked to a decreased prevalence of osteoporosis. However, the association between dietary...
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Folate deficiency may increase the risk for elevated TSH in patients with type 2 diabetes mellitus
BackgroundType 2 diabetes mellitus (T2DM) and thyroid dysfunction (TD) are two common chronic endocrine disorders that often coexist. Folate...
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Association between dietary folate intake and bone mineral density in a diverse population: a cross-sectional study
BackgroundOsteoporosis is a major public health problem, yet the association between dietary folate intake and bone health has been rarely studied....
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Folate, vitamin B12 and vitamin D status in healthy and active home-dwelling people over 70 years
BackgroundAgeing is characterised by physiological changes that can affect the nutrient availability and requirements. In particular, the status of...
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Human milk oligosaccharide composition following supplementation with folic acid vs (6S)-5-methyltetrahydrofolic acid during pregnancy and mediation by human milk folate forms
Supplementation with folic acid versus (6 S )-5-methyltetrahydrofolic acid (5-MTHF) results in different folate forms in human milk, with folic acid...
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Challenges in Pharmacokinetic Modelling of [18F]fluoro-PEG-folate PET/CT Imaging in Epithelial Ovarian Cancer Patients
PurposeTo describe the pharmacokinetic properties of the [ 18 F]fluoro-polyethylene glycol(PEG)-folate radiotracer in PET/CT imaging of patients with...
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Non-linear associations of serum and red blood cell folate with risk of cardiovascular and all-cause mortality in hypertensive adults
This study aims to assess the associations of serum and red blood cell (RBC) folate with cardiovascular and all-cause mortality in hypertensive...
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Association between red blood cell folate and Trichomonas vaginalis infection among women
BackgroundIncreased folic acid has been found to be latently protective against gynecological infection, including several kinds of vaginosis. In...
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Dose-response association between dietary folate and niacin intakes with diabetes among Chinese adults: a cross-sectional study
BackgroundThe aim of this study was to examine the relationship between dietary intake of folate and niacin and diabetes risk in Chinese adults.
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Co-occurrence of iron, folate, and vitamin A deficiency among pregnant women in eastern Ethiopia: a community-based study
BackgroundIt is well known that the magnitude of undernutrition in Ethiopia is unacceptably high. The burden of co-occurrence of iron, folate, and...
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Vitamin C and folate status in hereditary fructose intolerance
BackgroundHereditary fructose intolerance (HFI) is a rare inborn error of fructose metabolism caused by the deficiency of aldolase B. Since treatment...
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Predicting the effect of different folate doses on [68Ga]Ga-PSMA-11 organ and tumor uptake using physiologically based pharmacokinetic modeling
BackgroundFolate intake might reduce [ 68 Ga]Ga-PSMA-11 uptake in tissues due to a competitive binding to the PSMA receptor. For diagnostic imaging,...
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Dietary folate drives methionine metabolism to promote cancer development by stabilizing MAT IIA
Folic acid, served as dietary supplement, is closely linked to one-carbon metabolism and methionine metabolism. Previous clinical evidence indicated...
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Prenatal exposure to tobacco and adverse birth outcomes: effect modification by folate intake during pregnancy
BackgroundFetal exposure to tobacco increases the risk for many adverse birth outcomes, but whether diet mitigates these risks has yet to be...
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An infantile case of hereditary folate malabsorption with sudden development of pulmonary hemorrhage: a case report
BackgroundHereditary folate malabsorption—a rare disorder caused by impairment of the folate transporter—can develop into severe folate deficiency...
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Global strategies for the prevention of neural tube defects through the improvement of folate status in women of reproductive age
IntroductionNeural tube defects represent a global public health problem, mainly in countries where effective prevention strategies are not yet in...
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