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Cohort study investigating gout flares and management in UK general practice
BackgroundGout is the most common inflammatory arthritis and is almost exclusively managed in primary care, however the course and severity of the...
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Investigating protease-mediated peptides of inflammation and tissue remodeling as biomarkers associated with flares in psoriatic arthritis
BackgroundPsoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis. PsA disease involves flares, which are associated with...
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Breakthrough SARS-CoV-2 infection and disease flares in patients with rheumatoid arthritis: result from COVAD e-survey study
COVID-19 has been suggested as a possible trigger of disease flares in patients with rheumatoid arthritis (RA). However, factors associated with...
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The Impact of Systemic Lupus Erythematosus Flares on Clinical and Economic Outcomes: The CHAMOMILE Claims Database Study in Germany
IntroductionCHAMOMILE (CHaracteristics and impact of flares on clinicAl and econoMic OutcoMes In patients with systemic Lupus Erythematosus [SLE])...
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Association between Impella device support and elevated rates of gout flares: a retrospective propensity-matched study
BackgroundImpella is an advanced ventricular assist device frequently used as a bridge to heart transplantation. The association of Impella with...
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Clustering of gout-related comorbidities and their relationship with gout flares: a data-driven cluster analysis of eight comorbidities
ObjectivesTo study the aggregation of multiple comorbidities in people with gout and explore differences in prognosis of gout flares among different...
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Interleukin-1β inhibitors for the management of acute gout flares: a systematic literature review
ObjectivesThe objective of this systematic review was to assess the effects of interleukin-1β (IL-1β) inhibitors on gout flares.
Methods ... -
Kidney histopathology in predicting flares following drug withdrawal in proliferative lupus nephritis in clinical remission
Residual renal histopathological activity at clinical remission in Proliferative Lupus Nephritis (PLN) can predict renal flare upon immunosuppression...
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Flares in Lupus Nephritis: Risk Factors and Strategies for Their Prevention
Purpose of ReviewDiscuss the prognostic significance of kidney flares in patients with lupus nephritis, associated risk factors, and possible...
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Autoimmune bullous disorder flares following severe acute respiratory syndrome coronavirus 2 vaccination: a case series
BackgroundAutoimmune bullous disorders develop due to autoantibodies targeting intercellular adhesion proteins of hemidesmosomes and desmosomes and...
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Hyperuricemia and intravenous fat emulsion are risk factors for gout flares during active gastrointestinal bleeding: a case control study
ObjectiveIt is well-established that patients with a history of gout are more susceptible to experiencing gastrointestinal bleeding. Gout flare...
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The Flares of Low back pain with Activity Research Study (FLAReS): study protocol for a case-crossover study nested within a cohort study
BackgroundAlthough it is generally accepted that physical activity and flares of low back pain (LBP) are related, evidence for the directionality of...
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Factors contributing to flares of ulcerative colitis in North India- a case-control study
BackgroundUlcerative colitis is a relapsing and remitting disease that may be associated with flares. The causes of flares in the Indian setting are...
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The risk of nonalcoholic fatty liver disease in gout patients with frequent flares: a retrospective cohort study
ObjectiveNonalcoholic fatty liver disease (NAFLD) is a common chronic disease that is related to high serum uric acid; however, the association...
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Associations between season, climate, and pediatric alopecia areata flares in Providence, Rhode Island
Patients with alopecia areata (AA) may experience episodic hair loss that follows seasonal patterns. To assess associations between seasonal...
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Fluctuation and change of serum urate levels and flares in gout: results from the NOR-Gout study
AbstractA gout attack may evolve after a purine-rich diet or alcohol and after starting urate-lowering therapy (ULT). The relationships between...
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Prevalence and factors associated with flares following COVID-19 mRNA vaccination in patients with rheumatoid arthritis, psoriatic arthritis and spondyloarthritis: a national cohort study
ObjectiveTo determine prevalence and factors associated with flares post Coronavirus disease 2019 (COVID-19) mRNA vaccination in patients with...
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When underlying biology threatens the randomization principle — initial gout flares of urate-lowering therapy
Flare is the dominant feature of gout and occurs because of inflammatory response to monosodium urate crystals; prevention of gout flares should be...
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Predictors and outcomes of flares in chronic graft-versus-host disease
Chronic graft-versus-host disease (cGVHD) after allogeneic hematopoietic cell transplantation (HCT) requires prolonged immunosuppressive therapy...
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Synchronous disease onset and flares in siblings with PFAPA
BackgroundPeriodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) is a clinical syndrome of unclear etiology. PFAPA has...