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The synergistic mechanism of fibroblast growth factor 18 and integrin β1 in rat abdominal aortic aneurysm repair
BackgroundAbdominal aortic aneurysms have a high mortality rate. While surgery is the preferred treatment method, the biological repair of abdominal...
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The role of fibroblast growth factor 23 in regulation of phosphate balance
Phosphate is essential for numerous biological processes, and serum levels are tightly regulated to accomplish these functions. The regulation of...
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Analysis of serum insulin-like growth factor-1, fibroblast growth factor 23, and Klotho levels in girls with rapidly progressive central precocious puberty
To study the levels of serum insulin-like growth factor 1 (IGF-1), fibroblast growth factor 23 (FGF23), and Klotho, and to study their relationship...
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Durable response from fibroblast growth factor receptor inhibition in intrahepatic cholangiocarcinoma terminated by metachronous acute myeloid leukemia: a case report
IntroductionAdvances in the treatment of biliary tract cancer have been made possible through gains in genomic and epigenetic tumor understanding....
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Serum fibroblast growth factor-2 levels complement vital biomarkers for diagnosing heart failure
BackgroundEarly diagnosis of atrial fibrillation is important as it is crucial for improving patient outcomes. Fibroblast growth factor-2 (FGF2) may...
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Role of signaling pathways in age-related orthopedic diseases: focus on the fibroblast growth factor family
Fibroblast growth factor (FGF) signaling encompasses a multitude of functions, including regulation of cell proliferation, differentiation,...
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Fibroblast growth factor 21 in heart failure
Fibroblast growth factor 21 (FGF21) is a peptide hormone involved in energy homeostasis that protects against the development of obesity and diabetes...
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Fibroblast growth factor inhibition by molecular-targeted agents mitigates immunosuppressive tissue microenvironment in hepatocellular carcinoma
Background & aimsCombination immunotherapy refers to the use of immune checkpoint inhibitors (ICI) and molecular-targeted agents (MTA), which have...
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Efficacy of recombinant bovine basic fibroblast growth factor to reduce hemorrhage after cervical loop electrosurgical excision procedure
ObjectiveIt has been reported that recombinant bovine basic fibroblast growth factor (rbFGF) may possess possible biological functions in promoting...
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Relationship between serum fibroblast growth factor 19 and vascular endothelial growth factor and soluble klotho protein in type 1 diabetic children
BackgroundFibroblast growth factor 19 (FGF19) takes part in maintaining the balance of glycolipids and may be involved in complications of type 1...
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Research progress of fibroblast growth factor 23 in acute kidney injury
Fibroblast growth factor 23 (FGF23) is primarily produced in bones and mainly regulates calcium and phosphorus metabolism. The level of circulating...
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Effects of metformin on fibroblast growth factor 21 in patients with type 2 diabetes mellitus: faraway but so close
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance (IR) and hyperglycemia. The development of...
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Role of fibroblast growth factor-23 as an early marker of metabolic bone disease of prematurity
PurposeMetabolic bone disease of prematurity (MBDP) remains a significant cause of morbidity in extremely premature newborns. In high-risk patients,...
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Fibroblast growth factor 8 (FGF8) up-regulates gelatinase expression in chondrocytes through nuclear factor-κB p65
IntroductionGelatinases, namely MMP2 and MMP9, are involved in the natural turnover of articular cartilage, as well as the loss of the cartilage...
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Intact fibroblast growth factor 23 in heart failure with reduced and mildly reduced ejection fraction
BackgroundFibroblast growth factor-23 (FGF23) has been associated to left ventricular (LV) hypertrophy and heart failure (HF) severity. We aimed to...
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Fibroblast growth factor 21 attenuates ventilator-induced lung injury by inhibiting the NLRP3/caspase-1/GSDMD pyroptotic pathway
BackgroundVentilator-induced lung injury (VILI) is caused by overdistension of the alveoli by the repetitive recruitment and derecruitment of...
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Expression of fibroblast growth factor receptor 2 (FGFR2) in combined hepatocellular-cholangiocarcinoma and intrahepatic cholangiocarcinoma: clinicopathological study
Genetic alterations including fusions in fibroblast growth factor receptor 2 (FGFR2) are detected in 10–20% of intrahepatic cholangiocarcinoma...
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Fibroblast growth factor 23 as a biomarker of right ventricular dysfunction in pulmonary hypertension
BackgroundFibroblast growth factor 23 (FGF-23) has been associated with left ventricular hypertrophy (LVH) and heart failure. However, its role in...
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Infigratinib, a Selective Fibroblast Growth Factor Receptor Inhibitor, Suppresses Stent-Induced Tissue Hyperplasia in a Rat Esophageal Model
PurposeStent-induced tissue hyperplasia remains a challenge for the application of self-expanding metal stents in the management of esophageal...
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Application of polyglycolic acid sheets and basic fibroblast growth factor to prevent esophageal stricture after endoscopic submucosal dissection in pigs
BackgroundEndoscopic submucosal dissection (ESD) has been the first-line treatment for early-stage esophageal cancer. However, it often causes...
