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Emerging applications of phage therapy and fecal virome transplantation for treatment of Clostridioides difficile infection: challenges and perspectives
Clostridioides difficile , which causes life-threatening diarrheal disease, is considered an urgent threat to healthcare setting worldwide. The...
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Current perspectives on fecal microbiota transplantation in inflammatory bowel disease
Fecal microbiota transplantation (FMT) has emerged as a promising therapeutic modality within the domain of inflammatory bowel disease (IBD). While...
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Children with autism show differences in the gut DNA virome compared to non-autistic children: a case control study
BackgroundSeveral previous studies have identified a potential role that the gut microbiome can play in autism spectrum disorder (ASD) in children,...
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Features of the gut prokaryotic virome of Japanese patients with Crohn’s disease
Background/aimsThe gut virome is mainly composed of bacteriophages and influences gut homeostasis and pathogenic conditions. In this study, we...
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Murine sterile fecal filtrate is a potent pharmacological agent that exerts age-independent immunomodulatory effects in RAW264.7 macrophages
BackgroundSterile fecal filtrate (SFF) is being considered a safer alternative to fecal microbiota transplantation (FMT) therapy; however, its...
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A comprehensive guide to assess gut mycobiome and its role in pathogenesis and treatment of inflammatory bowel disease
Inflammatory bowel disease (IBD) is an immune mediated chronic inflammatory disorder of gastrointestinal tract, which has underlying multifactorial...
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Fecal Microbiota Transplantation in Hepatitis B e Antigen-Positive Chronic Hepatitis B Patients: A Pilot Study
BackgroundIntestinal flora plays a critical role in immunity against hepatitis B virus (HBV). Fecal Microbiota Transplantation (FMT) may be a...
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Abnormal Intestinal Microbiome in Medical Disorders and Potential Reversibility by Fecal Microbiota Transplantation
Reduction in diversity of the intestinal microbiome (dysbiosis) is being identified in many disease states, and studies are showing important...
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Gut microbiota signature in children with autism spectrum disorder who suffered from chronic gastrointestinal symptoms
BackgroundChildren diagnosed with autism spectrum disorder (ASD) frequently suffer from persistent gastrointestinal symptoms, such as constipation...
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A Perspective of the Urinary Microbiome in Lower Urinary Tract Infections — A Review
Purpose of ReviewGreater availability of sequencing methods has broadened the knowledge of the urinary microbiome in an environment previously...
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Lung microbiome: new insights into the pathogenesis of respiratory diseases
The lungs were long thought to be sterile until technical advances uncovered the presence of the lung microbial community. The microbiome of healthy...
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Alterations in microbiota of patients with COVID-19: potential mechanisms and therapeutic interventions
The global coronavirus disease 2019 (COVID-19) pandemic is currently ongoing. It is caused by severe acute respiratory syndrome coronavirus 2...
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Exploring the Complex Relationship Between Microbiota and Systemic Lupus Erythematosus
Purpose of ReviewSystemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by various autoantibodies and multi-organ....
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Biomarker-Based Assessment for Infectious Risk Before and After Heart Transplantation
Purpose of ReviewSurvival outcomes for heart transplant recipients have improved in recent decades, but infection remains a significant cause of...
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Microbial Symphony: Exploring the Role of the Gut in Osteoarthritis-Related Pain. A Narrative Review
One of the most common musculoskeletal disorders, osteoarthritis (OA), causes worldwide disability, morbidity, and poor quality of life by...
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Oral microbiome dysbiosis and gastrointestinal diseases: a narrative review
Mouth is the gateway to the total body wellness. Accordingly, oral microbiome influences overall health of an individual. Oral microbiome plays a key...
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Lessons Learned from Faecal Microbiota Transplantation in Cirrhosis
Purpose of ReviewWe examine recent developments in the treatment of cirrhosis by gut microbiome manipulation specifically focusing on the phase 1...
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Gut microbiota, intestinal permeability, and systemic inflammation: a narrative review
The intestine is the largest interface between the internal body and the external environment. The intestinal barrier is a dynamic system influenced...
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The role of the microbiota in the management of intensive care patients
The composition of the gut microbiota is highly dynamic and changes according to various conditions. The gut microbiota mainly includes...
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The Role of the Gut Microbiome in Health and Disease in the Elderly
Purpose of ReviewGrowing evidence supports the contribution of age in the composition and function of the gut microbiome, with specific findings...
