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Long-term prognosis after stapled and hand-sewn ileal pouch–anal anastomoses for familial adenomatous polyposis: a multicenter retrospective study
PurposeThe long-term prognosis of stapled and hand-sewn ileal pouch–anal anastomoses in familial adenomatous polyposis patients in Japan remains...
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Integrated genotype–phenotype analysis of familial adenomatous polyposis-associated hepatocellular adenomas
Familial adenomatous polyposis (FAP) is an autosomal dominant syndrome caused by a germline mutation in the adenomatous polyposis coli ( APC ) gene,...
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Clinical efficacy of metformin in familial adenomatous polyposis and the effect of intestinal flora
Background and aimsMetformin has been reported to inhibit the occurrence and development of colorectal cancer (CRC) by mediating changes in...
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Proctocolectomy and ileal J-pouch anastomosis for familial adenomatous polyposis in a paediatric patient
Familial adenomatous polyposis (FAP) is a well-described inherited syndrome, which presents with thousands of adenomas. Polyps appear in childhood or...
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Marital status after colorectal surgery in familial adenomatous polyposis: a nationwide multicenter study in Japan
BackgroundPatients with familial adenomatous polyposis (FAP) experience psychological and social challenges concerning future events such as marriage...
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Microbiome insights into pediatric familial adenomatous polyposis
BackgroundIndividuals with familial adenomatous polyposis (FAP) harbor numerous polyps with inevitable early progression to colon cancer. Complex...
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Risk of gastric adenoma and adenocarcinoma in patients with familial adenomatous polyposis in Japan: a nationwide multicenter study
BackgroundPatients with familial adenomatous polyposis (FAP) have an increased risk of develo** gastric neoplasms. However, the clinical course of...
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Surveillance Compliance and Quality of Life Assessment Among Surgical Patients with Familial Adenomatous Polyposis Syndrome
BackgroundFamilial adenomatous polyposis (FAP) syndrome has a near-100% lifetime risk of colorectal cancer. Early surveillance and prophylactic...
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Application of the ** robotic platform for familial adenomatous polyposis with ultra-low rectal cancer: exploration of minimally invasive and refined therapies
When a familial adenomatous polyposis (FAP) patient’s rectal polyp undergoes malignant transformation, the surgeon needs to consider how to balance...
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Desmoid Tumors in Familial Adenomatous Polyposis Patients: Favorable Outcomes with Multidisciplinary Management
ObjectiveIn this study, we aimed to describe the clinical features, management, and outcomes of desmoid tumors (DTs) in familial adenomatous...
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Incidental cancer in colectomy specimens from patients with familial adenomatous polyposis: single centre experience and literature review
BackgroundSince cancer development is inevitable in patients with familial adenomatous polyposis (FAP), we aimed to determine the incidence of...
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Usefulness of genoty** APC gene for individualizing management of patients with familial adenomatous polyposis
BackgroundColorectal polyp burden is crucial for the management of patients with familial adenomatous polyposis (FAP). However, accurate evaluation...
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Clinical features and distribution of the APC variant in duodenal and ampullary polyps in patients with familial adenomatous polyposis: a multicenter retrospective cohort study in Japan
BackgroundManagement of duodenal or ampullary adenomas in patients with familial adenomatous polyposis (FAP) is a major challenge for clinicians....
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Feasibility of underwater endoscopic mucosal resection for endoscopic management of gastric neoplasms in patients with familial adenomatous polyposis
BackgroundUnderwater endoscopic mucosal resection (UEMR) has been developed as an effective endoscopic intervention for colon, rectum, and duodenum...
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Superior rectal artery preservation to reduce anastomotic leak rates in familial adenomatous polyposis patients treated with total colectomy and ileorectal anastomosis
BackgroundTotal colectomy with ileorectal anastomosis (TC/IRA) is one of the prophylactic surgical options in patients with familial adenomatous...
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Long-term prognosis of familial adenomatous polyposis with or without mucosectomy
PurposeThis study primarily aimed to compare the long-term prognosis of patients who underwent total colectomy/proctocolectomy with or without...
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De novo familial adenomatous polyposis associated thyroid cancer with a c.2929delG frameshift deletion mutation in APC: a case report and literature review
BackgroundGermline mutations in the APC gene located on chromosome 5q 21–22 can lead to familial adenomatous polyposis (FAP) and the development of...
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Management of Familial Adenomatous Polyposis
Purpose of reviewThis paper reviews important aspects in the management of individuals with familial adenomatous polyposis (FAP).
Recent findings ... -
Curative resection via right hemicolectomy and regional lymph node dissection for colonic adenomatous polyposis of unknown etiology with adenocarcinomas localized in the right side of the colon: a case report
BackgroundAPC and MUTYH are both well-known colorectal polyposis causative genes. However, 30–50% of colorectal adenomatous polyposis cases are...
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The CHAMP-study: the CHemopreventive effect of lithium in familial AdenoMatous Polyposis; study protocol of a phase II trial
BackgroundFamilial adenomatous polyposis (FAP) is a rare autosomal dominant disease characterized by germline mutations in the Adenomatous Polyposis...
