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A ferroptosis-related signature predicts the clinical diagnosis and prognosis, and associates with the immune microenvironment of lung cancer
Targeting ferroptosis-related pathway is a potential strategy for treatment of lung cancer (LC). Consequently, exploration of ferroptosis-related...
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Integrated analysis and validation of ferroptosis-related genes and immune infiltration in acute myocardial infarction
BackgroundAcute myocardial infarction (AMI) is indeed a significant cause of mortality and morbidity in individuals with coronary heart disease....
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Ferroptosis-related genes, a novel therapeutic target for focal segmental glomerulosclerosis
Recent studies have suggested that ferroptosis participates in various renal diseases. However, its effect on focal segmental glomerulosclerosis...
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Identification of clinical prognostic factors and analysis of ferroptosis-related gene signatures in the bladder cancer immune microenvironment
BackgroundBladder cancer (BLCA) is a prevalent malignancy affecting the urinary system and poses a significant burden in terms of both incidence and...
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Ferroptosis-related genes prognostic signature for pancreatic cancer and immune infiltration: potential biomarkers for predicting overall survival
BackgroundPancreatic adenocarcinoma (PAAD) constitutes a lethal malignancy, notorious for its elevated mortality rates due to the difficulties in...
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Identification and verification of a novel signature that combines cuproptosis-related genes with ferroptosis-related genes in osteoarthritis using bioinformatics analysis and experimental validation
BackgroundExploring the pathogenesis of osteoarthritis (OA) is important for its prevention, diagnosis, and treatment. Therefore, we aimed to...
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Identification of hepatocellular carcinoma-related subtypes and development of a prognostic model: a study based on ferritinophagy-related genes
BackgroundHepatocellular carcinoma still has a high incidence and mortality rate worldwide, and further research is needed to investigate its...
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Construction and validation of a predictive nomogram for ferroptosis-related genes in osteosarcoma
BackgroundFerroptosis is a new type of cellular regulation of necrosis that has attracted great attention in recent years, which is different from...
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Bioinformatics-led discovery of ferroptosis-associated diagnostic biomarkers and molecule subtypes for tuberculosis patients
BackgroundFerroptosis is closely associated with the pathophysiological processes of many diseases, such as infection, and is characterized by the...
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Investigation of ferroptosis-associated molecular subtypes and immunological characteristics in lupus nephritis based on artificial neural network learning
BackgroundLupus nephritis (LN) is a severe complication of systemic lupus erythematosus (SLE) with poor treatment outcomes. The role and underlying...
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Integrative bioinformatics analysis to identify ferroptosis-related genes in non-obstructive azoospermia
PurposeThe objective of this study was to discern ferroptosis-related genes (FRGs) linked to non-obstructive azoospermia and investigate the...
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Ferroptosis-related signature and immune infiltration characterization in acute lung injury/acute respiratory distress syndrome
BackgroundAcute lung injury/acute respiratory distress syndrome (ALI/ARDS) is one of the most life-threatening diseases in the intensive care unit...
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Machine learning- and WGCNA-mediated double analysis based on genes associated with disulfidptosis, cuproptosis and ferroptosis for the construction and validation of the prognostic model for breast cancer
BackgroundDisulfidptosis, a recently discovered cellular death mechanism, has not been extensively studied in relation to breast cancer (BC)....
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Identification of ferroptosis related genes and pathways in prostate cancer cells under erastin exposure
BackgroundFew studies are focusing on the mechanism of erastin acts on prostate cancer (PCa) cells, and essential ferroptosis-related genes (FRGs)...
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Identification of ferroptosis-related molecular subtypes and a methylation-related ferroptosis gene prognostic signature in cervical squamous cell carcinoma
PurposeWe aimed to investigate the molecular characteristics of cervical squamous cell carcinoma (CESC) by analyzing ferroptosis-related gene (FRG)...
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Expression profiles and functions of ferroptosis-related genes in the placental tissue samples of early- and late-onset preeclampsia patients
BackgroundThe accumulation of reactive oxygen species (ROS) resulting from upregulated levels of oxidative stress is commonly implicated in...
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Ferroptosis-related lncRNAs guiding osteosarcoma prognosis and immune microenvironment
ObjectiveTo investigate the ferroptosis-related long non-coding RNAs (FRLncs) implicated in influencing the prognostic and immune microenvironment in...
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Role of ferroptosis-related genes in coronary atherosclerosis and identification of key genes: integration of bioinformatics analysis and experimental validation
BackgroundCoronary atherosclerosis (CA) is the most common type of atherosclerosis. However, the inherent pathogenesis and mechanisms of CA are...
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Classification of colorectal carcinoma subtypes based on ferroptosis-associated molecular markers
BackgroundFerroptosis is associated with the development of many cancers; the molecular features of colorectal carcinoma (CRC) based on...
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Prediction of overall survival based upon a new ferroptosis-related gene signature in patients with clear cell renal cell carcinoma
BackgroundClear cell renal cell carcinoma (ccRCC) is the most common and lethal renal cell carcinoma (RCC) histological subtype. Ferroptosis is a...
