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Implications of FRAX® adjusted for recent fracture on the indication of treatment in an FLS
SummaryWe analyzed the practical consequences of applying an adjusted FRAX® for recent fractures in a FLS. After analyzing 2777 patients, we...
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Improving bone health in prostate cancer patients starting androgen deprivation therapy: does Fracture Risk Assessment Tool (FRAX®) enhance stratification and targeted management?
SummaryAndrogen deprivation therapy for prostate cancer can lead to osteoporosis and increased fracture risk. The Fracture Risk Assessment Tool...
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Validation of the Taiwan FRAX® calculator for the prediction of fracture risk
SummaryThe Taiwan FRAX® calculator was validated to predict incident fractures preliminarily. Cutoffs of FRAX probability for predicting major...
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FREM predicts 10-year incident fracture risk independent of FRAX® probability: a registry-based cohort study
SummaryThe Danish Fracture Risk Evaluation Model (FREM) was found to predict fracture risk independent of 10-year fracture probability derived with...
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Cost-effectiveness of FRAX®-based intervention thresholds for management of osteoporosis in Singaporean women
SummaryCost-effectiveness analysis of FRAX® intervention thresholds (ITs) in Singaporean women > 50 years of age showed that generic alendronate was...
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FRAX® with or without BMD and TBS predicts fragility fractures in community-dwelling rural southern Indian postmenopausal women
SummaryThis study from southern India showed that FRAX® with or without BMD or TBS predicted fragility vertebral fractures at a cut-off of ≥ 9% for...
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Efficacy of teriparatide compared with risedronate on FRAX®-defined major osteoporotic fractures: results of the VERO clinical trial
SummaryFRAX ® calculates the 10-year probability of major osteoporotic fractures (MOF), which are considered to have a greater clinical impact than...
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Predictive capacity of FRAX in a spanish region with a hip fracture rate close to the national mean
BackgroundIt is known that standardized incidence rates of hip fracture vary among older people in Spain. So far, the results published on the...
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Selection for treatment of patients at high risk of fracture by the short versus long term prediction models — data from the Belgian FRISBEE cohort
SummaryOur imminent model was less sensitive but more selective than FRAX® in the choice of treatment to prevent imminent fractures. This new model...
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Evolution of bone densitometry parameters and risk of fracture in coeliac disease: a 10-year perspective
BackgroundMetabolic bone disease is frequently found in patients with coeliac disease (CD). Despite its high prevalence, international guidelines are...
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Accuracy of the Fracture Risk Assessment Tool for judging pharmacotherapy initiation for primary osteoporosis
IntroductionThis study aimed to determine whether the Fracture Risk Assessment Tool (FRAX ® ) is useful in assessing the criteria for the initiation...
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Adjusting conventional FRAX estimates of fracture probability according to the number of prior falls in the preceding year
SummaryA greater propensity to falling is associated with higher fracture risk. This study provides adjustments to FRAX-based fracture probabilities...
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Race-specific FRAX models are evidence-based and support equitable care: a response to the ASBMR Task Force report on Clinical Algorithms for Fracture Risk
Task Force on ‘Clinical Algorithms for Fracture Risk’ commissioned by the American Society for Bone and Mineral Research (ASBMR) Professional...
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Adjusting conventional FRAX estimates of fracture probability according to the number of prior fractures
SummaryThe risk of a recurrent fragility fracture is high following a first fracture and higher still with more than one prior fracture. This study...
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Effectiveness of romosozumab in patients with osteoporosis at high fracture risk: a Japanese real-world study
IntroductionTo describe the real-world use of romosozumab in Japan, we conducted a chart review of > 1000 Japanese patients with osteoporosis (OP) at...
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Epidemiology of hip fracture in Qatar and development of a country specific FRAX model
SummaryHip fracture data were retrieved from electronical medical records for the years 2017–2019 in the State of Qatar and used to create a FRAX®...
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Can frailty in conjunction with FRAX identify additional women at risk of fracture - a longitudinal cohort study of community dwelling older women
BackgroundFracture risk assessment is still far from perfect within the geriatric population. The overall aim of this study is to better identify...
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An assessment of intervention thresholds for high fracture risk in Chile
SummaryAssessment and treatment pathways using FRAX-based intervention thresholds in Chile can be used to identify patients at high risk of fracture...
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Temporal changes in access to FRAX® in Thailand between 2010 and 2018
SummaryThe usage of FRAX® tool in Thailand and other countries was explored using Google Analytics data. Over the period 2010–2018, Thailand ranked...
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Incidence of hip fracture in Saudi Arabia and the development of a FRAX model
SummaryA prospective hospital-based survey in representative regions of Saudi Arabia determined the incidence of fractures at the hip. The hip...