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1. Hematopoiesis in the spleen after engraftment in unrelated cord blood transplantation evaluated by ¹⁸F-FLT PET imaging

   Cord blood is an important donor source for allogeneic hematopoietic stem cell transplantation (allo-HSCT), with its unique composition and quality...

   Hiroaki Araie, Naoko Hosono, ... Takahiro Yamauchi in International Journal of Hematology

   Article Open access 02 October 2023
   

2. Radiomic analysis will add differential diagnostic value of benign and malignant pulmonary nodules: a hybrid imaging study based on [¹⁸F]FDG and [¹⁸F]FLT PET/CT

   Purpose

   To investigate the clinical value of radiomic analysis on [ ¹⁸ F]FDG and [ ¹⁸ F]FLT PET on the differentiation of [ ¹⁸ F]FDG-avid benign and...

   **g Ning, Can Li, ... Baixuan Xu in Insights into Imaging

   Article Open access 19 November 2023
   

3. Hematopoietic status of the whole-body bone marrow in hypoplastic acute promyelocytic leukemia as evaluated by ¹⁸F-FLT PET/MRI

   Hiroaki Araie, Toshiki Tasaki, ... Takahiro Yamauchi in Annals of Hematology

   Article 08 May 2023
   

4. Voxel-Based Analysis of the Relation of 3′-Deoxy-3′-[¹⁸F]fluorothymidine ([¹⁸F]FLT) PET and Diffusion-Weighted (DW) MR Signals in Subcutaneous Tumor Xenografts Does Not Reveal a Direct Spatial Relation of These Two Parameters

   Purpose

   Multimodal molecular imaging allows a direct coregistration of different images, facilitating analysis of the spatial relation of various...

   Sonja Schelhaas, Lynn Johann Frohwein, ... Andreas H. Jacobs in Molecular Imaging and Biology

   Article Open access 09 November 2021
   

5. A phase I trial of sorafenib with whole brain radiotherapy (WBRT) in breast cancer patients with brain metastases and a correlative study of FLT-PET brain imaging

   Purpose

   Sorafenib has demonstrated anti-tumor efficacy and radiosensitizing activity preclinically and in breast cancer. We examined sorafenib in...

   Aki Morikawa, Milan Grkovski, ... Andrew D. Seidman in Breast Cancer Research and Treatment

   Article 10 June 2021
   

6. Comparison of the [¹⁸F]-FDG and [¹⁸F]-FLT PET Tracers in the Evaluation of the Preclinical Proton Therapy Response in Hepatocellular Carcinoma

   Purpose

   The main objective of the present study was to compare the 2-deoxy-2-[ ¹⁸ F]fluoro-D-glucose ([ ¹⁸ F]-FDG) and 3′-[ ¹⁸ F]fluoro-3′-deoxythymidine ([

   David Brasse, Hélène Burckel, ... Frédéric Boisson in Molecular Imaging and Biology

   Article 13 April 2021
   

7. FLT-PET for the assessment of systemic sarcoidosis including cardiac and CNS involvement: a prospective study with comparison to FDG-PET

   Background

   2-deoxy-2-[18F]fluoro- d -glucose’s (FDG) biodistribution limits the evaluation of cardiac sarcoidosis (CS) and neurosarcoidosis (NS). While...

   Patrick Martineau, Matthieu Pelletier-Galarneau, ... David Birnie in EJNMMI Research

   Article Open access 10 December 2020
   

8. ¹⁸F-FLT PET/CT imaging for early monitoring response to CDK4/6 inhibitor therapy in triple negative breast cancer

   Purpose

   Our study was to investigate ¹⁸ F-FLT PET/CT imaging monitor the early response of CDK4/6 inhibitor therapy in triple negative breast cancer...

   Guang Ma, Cheng Liu, ... Zhongyi Yang in Annals of Nuclear Medicine

   Article 10 March 2021
   

9. Diagnostic Value of Circulating PIGF in Combination with Flt-1 in Early Cervical Cancer

   The utility of placental growth factor (PlGF) and its receptor VEGFR-1 (Flt-1) as biomarkers for cervical cancer has not been clarified yet. To...

   Shou-hua Yang, **ao-ling Wang, ... Shao-hai Wang in Current Medical Science

   Article 29 October 2020

10. Molecular imaging with FLT: a case of Cassandra’s curse?

    Rodney J. Hicks in European Journal of Nuclear Medicine and Molecular Imaging

    Article 03 June 2021

11. Sunitinib in Patients with Metastatic Colorectal Cancer (mCRC) with FLT-3 Amplification: Results from the Targeted Agent and Profiling Utilization Registry (TAPUR) Study

    Background

    TAPUR is a pragmatic, phase II basket study evaluating the antitumor activity of commercially available targeted agents in patients with...

    Tareq Al Baghdadi, Elizabeth Garrett-Mayer, ... Richard L. Schilsky in Targeted Oncology

    Article 17 October 2020
    

12. High efficacy of particle beam therapies against tumors under hypoxia and prediction of the early stage treatment effect using 3'-deoxy-3'-[¹⁸F]fluorothymidine positron emission tomography

    Objective

    Compared with radiation therapy using photon beams, particle therapies, especially those using carbons, show a high relative biological...

    Akira Makino, Kyo Kume, ... Yasushi Kiyono in Annals of Nuclear Medicine

    Article Open access 19 October 2023
    

13. Exploring the applicability of a lesion segmentation method on [¹⁸F]fluorothymidine PET/CT images in diffuse large B-cell lymphoma

    Background and purpose

    The determination of the total metabolic tumour volume based on [ ¹⁸ F]fluorothymidine ([ ¹⁸ F]FLT) PET/CT images in diffuse large...

    Germán Pitarch, Yamila Rotstein Habarnau, ... María Bastianello in European Journal of Hybrid Imaging

    Article Open access 25 December 2023
    

14. Proliferation and apoptosis after whole-body irradiation: longitudinal PET study in a mouse model

    Purpose

    A reliable method for regional in vivo imaging of radiation-induced cellular damage would be of great importance for the detection of...

    Maria Meindl, Alexandra Bläske, ... Peter Bartenstein in European Journal of Nuclear Medicine and Molecular Imaging

    Article Open access 05 October 2023
    

15. Diagnostic value of PET/CT with ¹¹C-methionine (MET) and ¹⁸F-fluorothymidine (FLT) in newly diagnosed glioma based on the 2016 WHO classification

    Background

    The molecular features of isocitrate dehydrogenase ( IDH ) mutation and chromosome 1p and 19q (1p/19q) codeletion status have pivotal role...

    Tomoya Ogawa, Nobuyuki Kawai, ... Takashi Tamiya in EJNMMI Research

    Article Open access 07 May 2020
    

16. Incidental ¹⁸F-FDG myocardial uptake revealed as physiological lesion by ¹⁸F-FLT PET/CT

    Kanako Chujo, Takashi Norikane, ... Yoshihiro Nishiyama in Journal of Nuclear Cardiology

    Article 22 April 2021
    

17. ¹⁸F-fluorothymidine (FLT)-PET and diffusion-weighted MRI for early response evaluation in patients with small cell lung cancer: a pilot study

    Background

    Small cell lung cancer (SCLC) is an aggressive cancer often presenting in an advanced stage and prognosis is poor. Early response...

    Tine Nøhr Christensen, Seppo W. Langer, ... Barbara Malene Fischer in European Journal of Hybrid Imaging

    Article Open access 27 January 2020
    

18. Dual time point [¹⁸F]FLT-PET for differentiating proliferating tissues vs non-proliferating tissues

    Purpose

    For differentiating tumor from inflammation and normal tissues, fluorodeoxyglucose ([ ¹⁸ F]FDG) dual time point PET could be helpful. Albeit [ ¹⁸ ...

    Pierre Lovinfosse, Caroline Rousseau, ... Olivier-François Couturier in EJNMMI Research

    Article Open access 12 December 2019
    

19. PD1 blockade alters cell-cycle distribution and affects 3′-deoxy-3′-[¹⁸F]fluorothymidine uptake in a mouse CT26 tumor model

    Objective

    We previously reported that alterations of the tumor microenvironment (TME) by programmed death receptor-1 (PD1) blockade affected tumor...

    Motofumi Suzuki, Takuma Matsuda, ... Mikako Ogawa in Annals of Nuclear Medicine

    Article 15 August 2022
    

20. Evaluating the Accuracy of FUCCI Cell Cycle In Vivo Fluorescent Imaging to Assess Tumor Proliferation in Preclinical Oncology Models

    Purpose

    The primary goal of this study is to evaluate the accuracy of the fluorescence ubiquitination cell cycle indicator (FUCCI) system with...

    Yun Lu, Adriana V. F. Massicano, ... Anna G. Sorace in Molecular Imaging and Biology

    Article 01 June 2022