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The amyotrophic lateral sclerosis exposome: recent advances and future directions
Amyotrophic lateral sclerosis (ALS) is a fatal disease of motor neuron degeneration with typical survival of only 2–5 years from diagnosis. The...
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The contribution of the exposome to the burden of cardiovascular disease
Large epidemiological and health impact assessment studies at the global scale, such as the Global Burden of Disease project, indicate that chronic...
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Exposome and Skin: Part 1. Bibliometric Analysis and Review of the Impact of Exposome Approaches on Dermatology
IntroductionMost skin disorders, such as atopic dermatitis, psoriasis, skin cancer or age-related skin issues, are the result of a complex...
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Predicting self-perceived general health status using machine learning: an external exposome study
BackgroundSelf-perceived general health (SPGH) is a general health indicator commonly used in epidemiological research and is associated with a wide...
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Environmental neuroscience linking exposome to brain structure and function underlying cognition and behavior
Individual differences in human brain structure, function, and behavior can be attributed to genetic variations, environmental exposures, and their...
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Probing the digital exposome: associations of social media use patterns with youth mental health
Recently, the U.S. Surgeon General issued an advisory highlighting the lack of knowledge about the safety of ubiquitous social media use on...
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Non-targeted analysis (NTA) and suspect screening analysis (SSA): a review of examining the chemical exposome
AbstractNon-targeted analysis (NTA) and suspect screening analysis (SSA) are powerful techniques that rely on high-resolution mass spectrometry...
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Population-wide measures due to the COVID-19 pandemic and exposome changes in the general population of Cyprus in March–May 2020
Non-pharmacological interventions (e.g., stay-at-home orders, school closures, physical distancing) implemented during the COVID-19 pandemic are...
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Exposome and Skin. Part 2. The Influential Role of the Exposome, Beyond UVR, in Actinic Keratosis, Bowen’s Disease and Squamous Cell Carcinoma: A Proposal
Actinic keratosis (AK) is the main risk factor for the development of cutaneous invasive squamous cell carcinoma (SCC). It represents the first sign...
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Environmental risk factors of type 2 diabetes—an exposome approach
Type 2 diabetes is one of the major chronic diseases accounting for a substantial proportion of disease burden in Western countries. The majority of...
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The public health exposome and pregnancy-related mortality in the United States: a high-dimensional computational analysis
BackgroundRacial inequities in maternal mortality in the U.S. continue to be stark.
MethodsThe 2015–2018, 4-year total population, county-level,...
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Gut microbial ecology and exposome of a healthy Pakistani cohort
BackgroundPakistan is a multi-ethnic society where there is a disparity between dietary habits, genetic composition, and environmental exposures. The...
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Investigating causal relationships between exposome and human longevity: a Mendelian randomization analysis
BackgroundEnvironmental factors are associated with human longevity, but their specificity and causality remain mostly unclear. By integrating the...
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The Role of the Environment and Exposome in Atopic Dermatitis
Purpose of reviewAtopic dermatitis (AD) is a chronic inflammatory skin disorder affecting up to 20% of children and up to 5% of adults worldwide,...
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Lung Health and the Exposome How Environmental Factors Influence Lung Health
This book is ideal for the practicing clinician looking to better understand how our environment impacts the lung. A compilation of reviews explores...
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Associations between neighborhood built, social, or toxicant conditions and child externalizing behaviors in the Detroit metro area: a cross-sectional study of the neighborhood ‘exposome’
BackgroundThe specific ‘active ingredients’ through which neighborhood disadvantage increases risk for child psychopathology remains unclear, in...
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Applying the exposome concept in birth cohort research: a review of statistical approaches
The exposome represents the totality of life course environmental exposures (including lifestyle and other non-genetic factors), from the prenatal...
