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Are we romanticizing traditional knowledge? A plea for more experimental studies in ethnobiology
In answer to the debate question "Is ethnobiology romanticizing traditional practices, posing an urgent need for more experimental studies evaluating...
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Research Progress on the Experimental Model and Underlying Mechanistic Studies of Tension-Type Headaches
Purpose of ReviewTension-type headaches (TTH) significantly diminish patients’ quality of life and increase absenteeism, thereby imposing a...
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Establishment of an animal model of adjacent segment degeneration after interbody fusion and related experimental studies
BackgroundDegenerative spine conditions are common and frequent clinical diseases, and adjacent segment disease (ASD) after spinal fusion (SF) is a...
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Patient preferences for epilepsy treatment: a systematic review of discrete choice experimental studies
BackgroundThis review aimed to 1) identify and assess the quality of discrete choice experiments (DCEs) examining preferences related to epilepsy...
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Exercise Snacks and Other Forms of Intermittent Physical Activity for Improving Health in Adults and Older Adults: A Sco** Review of Epidemiological, Experimental and Qualitative Studies
Exercise snacks, including other variants of brief intermittent bouts, are an emerging approach for increasing physical activity, although their...
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The Effects of IRL-1620 in Post-ischemic Brain Injury: A Systematic Review and Meta-analysis of Experimental Studies
BackgroundSovateltide (IRL-1620), an endothelin B receptor agonist, has previously demonstrated neuroprotective and neuroregenerative effects in...
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Fluid management strategies and their interaction with mechanical ventilation: from experimental studies to clinical practice
Patients on mechanical ventilation may receive intravenous fluids via restrictive or liberal fluid management. A clear and objective differentiation...
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Toxicological Impact of Bisphenol A on Females’ Reproductive System: Review Based on Experimental and Epidemiological Studies
The study encompassing research papers documented in the last two decades pertaining to the possible influence of bisphenol A (BPA) on the fertility...
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A novel combination of sitagliptin and melatonin ameliorates T2D manifestations: studies on experimental diabetic models
IntroductionType 2 diabetes (T2D) is an endocrine disorder characterized by hyperglycemia, insulin resistance, dysregulated glucose and lipid...
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Experimental and molecular docking studies of quercetin and vitamin E with diabetes-associated mitochondrial-ATPase as anti-apoptotic therapeutic strategies
PurposeResearches have shown the relevance of antioxidants in the management of several diseases. In the present study, the effects of quercetin and...
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Anti-inflammatory and antioxidative effects of gallic acid on experimental dry eye: in vitro and in vivo studies
BackgroundTo investigate the anti-inflammatory and antioxidative effects of gallic acid (GA) on human corneal epithelial cells (HCECs) and RAW264.7...
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An update on the role and potential mechanisms of clock genes regulating spermatogenesis: A systematic review of human and animal experimental studies
Circadian clocks can be traced in nearly all life kingdoms, with the male reproductive system no exception. However, our understanding of the...
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Experimental Design and Reproducibility in Preclinical Animal Studies
This highly-readable text provides grounds on how to plan and conduct animal experiments that can be reproduced by others. The book touches...
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Shexiang Tongxin Drop** Pill Allieviates Heart Failure via Extracellula Matrix-Receptor Interaction Pathways Based on RNA-Seq Transcriptomics and Experimental Studies
ObjectiveTo investigate the protective mechanisms of Chinese medicine Shexiang Tongxin Drop** Pills (STDP) on heart failure (HF).
Methods ... -
Radioprotective Effects of a Semicircular X-ray Shielding Device for Operators During CT Fluoroscopy-Guided Interventional Procedures: Experimental and Clinical Studies
PurposeTo evaluate, experimentally and clinically, the radioprotective effects of a semicircular X-ray shielding device for operators during CT...
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Using public clinical trial reports to probe non-experimental causal inference methods
BackgroundNon-experimental studies (also known as observational studies) are valuable for estimating the effects of various medical interventions,...
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Explaining the effect on food selection of altering availability: two experimental studies on the role of relative preferences
BackgroundIncreasing the availability of healthier or plant-based foods increases their selection. The current studies aimed to examine the extent to...
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Tinnitus treatment: an experimental study
ObjectiveThe objective of the present study was to compare the effectiveness of the selected tinnitus management protocols for the experimental...
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Experimental rat models for Hashimoto’s thyroiditis
PurposeHashimoto’s thyroiditis (HT) is an autoimmune thyroid disease characterized by T lymphocyte-mediated destruction of thyroid follicles. To...
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Tissue thermal effect during lithotripsy and tissue ablation in endourology: a systematic review of experimental studies comparing Holmium and Thulium lasers
PurposeWe looked into the Thulium: yttrium-aluminum-garnet (TM:YAG), Thulium Fibre laser (TFL) and Holmium: yttrium-aluminum-garnet (Ho:YAG) thermal...
