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Machine Learning Approaches to Predict Asthma Exacerbations: A Narrative Review
The implementation of artificial intelligence (AI) and machine learning (ML) techniques in healthcare has garnered significant attention in recent...
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Prognostic factors of pulmonary exacerbations severity in pediatric bronchiectasis: a retrospective cohort study
BackgroundPulmonary exacerbations have been found to negatively impact the natural course of pediatric bronchiectasis. However, prognostic factors...
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Acuity of asthma exacerbations in Alberta, Canada is increasing: a population-based study
BackgroundAsthma is a common respiratory illness affecting 2.8 million Canadians, including 9.7% of Albertans. Prior studies showed a substantial...
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Associations between the EQ-5D-5L and exacerbations of chronic obstructive pulmonary disease in the ETHOS trial
PurposeExacerbations of chronic obstructive pulmonary disease (COPD) are associated with deteriorating health and health-related quality of life...
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The relationship between changes in peak expiratory flow and asthma exacerbations in asthmatic children
BackgroundAsthma is one of the most common chronic airway diseases in children. Preventing asthma exacerbation is one of the objectives of all asthma...
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LPS binding protein and activation signatures are upregulated during asthma exacerbations in children
Asthma exacerbations in children are associated with respiratory viral infection and atopy, resulting in systemic immune activation and infiltration...
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Effects of treatment with corticosteroids on human rhinovirus-induced asthma exacerbations in pediatric inpatients: a prospective observational study
BackgroundHuman rhinoviruses (HRVs) infection is a common cause of exacerbations in pediatric patients with asthma. However, the effects of...
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Effect of Broncho-Vaxom (OM-85) on the frequency of chronic obstructive pulmonary disease (COPD) exacerbations
BackgroundEfforts have been made to reduce the risk of chronic obstructive pulmonary disease (COPD) exacerbations using a variety of measures....
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Elevated Eosinophil Counts in Acute Exacerbations of Bronchiectasis: Unveiling a Distinct Clinical Phenotype
BackgroundNon-cystic fibrosis bronchiectasis is a chronic respiratory disease characterized by bronchial dilation. However, the significance of...
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Blood eosinophil variability in patients presenting with acute exacerbations of COPD within the past year and its correlation with treatment plan
BackgroundChronic obstructive pulmonary disease (COPD) is an acknowledged contributor to universal fatality and morbidity. Using biomarkers to...
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Bacterial interactome disturbance in chronic obstructive pulmonary disease clinical stability and exacerbations
RationaleOur understanding of airway dysbiosis in chronic obstructive pulmonary disease (COPD) remains incomplete, which may be improved by...
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Machine learning for prediction of asthma exacerbations among asthmatic patients: a systematic review and meta-analysis
BackgroundAsthma exacerbations reduce the patient’s quality of life and are also responsible for significant disease burdens and economic costs....
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BEAT CF pulmonary exacerbations core protocol for evaluating the management of pulmonary exacerbations in people with cystic fibrosis
BackgroundCystic fibrosis (CF) is a rare, inherited, life-limiting condition predominantly affecting the lungs, for which there is no cure. The...
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Asthma Exacerbations in Severe Asthma: Why Systemic Corticosteroids May not Always Be the Best Treatment Option
PurposeAdvances in the management of severe, eosinophilic asthma have improved, but asthma exacerbations continue to occur. This review aims to look...
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Cell-free DNA levels associate with COPD exacerbations and mortality
The question addressed by the studyGood biological indicators capable of predicting chronic obstructive pulmonary disease (COPD) phenotypes and...
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A parametric model to jointly characterize rate, duration, and severity of exacerbations in episodic diseases
BackgroundThe natural history of many chronic diseases is characterized by periods of increased disease activity, commonly referred to as flare-ups...
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COPD exacerbations and patient-reported outcomes according to post-bronchodilator FEV1 – a post-hoc analysis of pooled data
BackgroundManagement strategies of chronic obstructive pulmonary disease (COPD) need to be tailored to the forced expiratory volume in one second (FEV
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Relationship between airway inflammation, small airway dysfunction, and frequency of acute exacerbations in patients with chronic obstructive pulmonary disease
ContextRecurrent exacerbations in COPD patients are associated with accelerated reduction in lung function. Airway inflammation and small airway...
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Statins did not reduce the frequency of exacerbations in individuals with COPD and cardiovascular comorbidities in the COSYCONET cohort
BackgroundThe evidence regarding effects of statins on exacerbation risk in COPD remains controversial. Previous studies often excluded patients with...
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Incidence and causative agent distribution of viral-induced paediatric asthma exacerbations under strict infection control measures: a single-centre retrospective study in Japan
BackgroundThe prevalence of respiratory viruses in children changed under strict infection control measures during the coronavirus disease 2019...
