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Lipolysis supports bone formation by providing osteoblasts with endogenous fatty acid substrates to maintain bioenergetic status
Bone formation is a highly energy-demanding process that can be impacted by metabolic disorders. Glucose has been considered the principal substrate...
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Total polyunsaturated fatty acid intake and the risk of non-alcoholic fatty liver disease in Chinese Han adults: a secondary analysis based on a case–control study
BackgroundPrevious studies have revealed obesity, nutrition, lifestyle, genetic and epigenetic factors may be risk factors for the occurrence and...
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The gut-liver nexus: exploring gut microbiota dysbiosis in non-alcoholic fatty liver disease and its therapeutic implications
BackgroundThe human gut microbiota (GM) is a diverse ecosystem crucial for health, impacting physiological processes across the host's body. This...
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Associations of polyunsaturated fatty acids with cardiovascular disease and mortality: a study of NHANES database in 2003–2018
BackgroundThis study was to explore the association between dietary polyunsaturated fatty acids (PUFAs) consumption and cardiovascular diseases...
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The association of polyunsaturated fatty acids and asthma: a cross-sectional study
BackgroundTo examine the relationships between polyunsaturated fatty acids (PUFAs) dietary intake and asthma in children.
MethodsIn this...
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Microbial short-chain fatty acids regulate drug seeking and transcriptional control in a model of cocaine seeking
Cocaine use disorder represents a public health crisis with no FDA-approved medications for its treatment. A growing body of research has detailed...
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Countering impaired glucose homeostasis during catch-up growth with essential polyunsaturated fatty acids: is there a major role for improved insulin sensitivity?
Background/ObjectivesCatch-up growth, an important risk factor for later obesity and type 2 diabetes, is often characterized by a high rate of fat...
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Ablation of sphingosine kinase 2 suppresses fatty liver-associated hepatocellular carcinoma via downregulation of ceramide transfer protein
Hepatocellular carcinoma (HCC) accounts for 90% of primary liver cancer, the third leading cause of cancer-associated death worldwide. With the...
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Protein content and amino acid composition in the diet of Danish vegans: a cross-sectional study
BackgroundA growing proportion of the population are replacing their dietary animal protein with plant protein. A particular example of this trend is...
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Amino acid metabolism in health and disease
Amino acids are the building blocks of protein synthesis. They are structural elements and energy sources of cells necessary for normal cell growth,...
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Recompensation in cirrhosis: unravelling the evolving natural history of nonalcoholic fatty liver disease
Recompensation has gained increasing attention in the field of cirrhosis, particularly in chronic liver disease with a definite aetiology. The...
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Non-alcoholic fatty liver disease and gut microbial dysbiosis- underlying mechanisms and gut microbiota mediated treatment strategies
Non-alcoholic fatty liver disease (NAFLD) is by far the most prevalent form of liver disease worldwide. It’s also the leading cause of liver-related...
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Effects of rye inclusion in dog food on fecal microbiota and short-chain fatty acids
BackgroundRye intake has been associated with beneficial effects on health in human interventions, possibly due to dietary fiber in rye. In dogs, few...
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Non-alcoholic fatty liver disease and gestational diabetes mellitus: a bidirectional two-sample mendelian randomization study
PurposePrevious observational studies have revealed a potential link between non-alcoholic fatty liver disease (NAFLD) and gestational diabetes...
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Associations of serum long-chain fatty acids with multiple organ involvement in patients with sarcoidosis
BackgroundFatty acids have diverse immunomodulatory functions and the potential to be associated with inflammatory responses in sarcoidosis.
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Metabolic dysfunction-associated fatty liver disease and implications for cardiovascular risk and disease prevention
The newly proposed term “metabolic dysfunction-associated fatty liver disease” (MAFLD) is replacing the old term “non-alcoholic fatty liver disease”...
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Noninvasive Diagnostic Technique for Nonalcoholic Fatty Liver Disease Based on Features of Tongue Images
ObjectiveTo investigate a new noninvasive diagnostic model for nonalcoholic fatty liver disease (NAFLD) based on features of tongue images.
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Honokiol acts as an AMPK complex agonist therapeutic in non-alcoholic fatty liver disease and metabolic syndrome
BackgroundNon-alcoholic fatty liver (NAFLD) and its related metabolic syndrome have become major threats to human health, but there is still a need...
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Clinical manifestations and management of fatty acid oxidation disorders
Fatty acid oxidation disorders (FAOD) are a group of rare, autosomal recessive, metabolic disorders caused by variants of the genes for the enzymes...
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Short-Chain Fatty Acids—A Product of the Microbiome and Its Participation in Two-Way Communication on the Microbiome-Host Mammal Line
Purpose of ReviewThe review aims to describe short-chain fatty acids (SCFAs) as metabolites of bacteria, their complex influence on whole-body...
