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Astrocyte dysregulation as an epileptogenic factor: a systematic review
BackgroundEpilepsy initiation involves multifactorial etiologies, including genetic susceptibility, structural anomalies, and glial cell...
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Predictive model for epileptogenic tubers from all tubers in patients with tuberous sclerosis complex based on 18F-FDG PET: an 8-year single-centre study
BackgroundMore than half of patients with tuberous sclerosis complex (TSC) suffer from drug-resistant epilepsy (DRE), and resection surgery is the...
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Absence seizures in lesion-related epilepsy
BackgroundIn the new International League Against Epilepsy (ILAE) classification of seizure types, generalized seizures such as absence seizures...
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Implementation of a 7T Epilepsy Task Force consensus imaging protocol for routine presurgical epilepsy work-up: effect on diagnostic yield and lesion delineation
ObjectiveRecently, the 7 Tesla (7 T) Epilepsy Task Force published recommendations for 7 T magnetic resonance imaging (MRI) in patients with...
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Stereoelectroencephalography-guided radiofrequency thermocoagulation of the epileptogenic zone: a potential treatment and prognostic indicator for subsequent excision surgery
PurposeTo evaluate the safety and efficacy of stereoelectroencephalography (SEEG)-guided radiofrequency thermocoagulation (RFTC) for drug-resistant...
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Factors influencing the detection of treatable epileptogenic lesions on MRI. A randomized prospective study
BackgroundTo prospectively analyze factors associated with detecting epileptogenic lesions on MRI within the work-sharing process of neurologists,...
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18F-FDG-PET glucose hypometabolism pattern in patients with epileptogenic hypothalamic hamartoma
Epileptogenic hypothalamic hamartoma is characterized by intractable gelastic seizures. A systematic analysis of the overall brain metabolic pattern...
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Neurite orientation dispersion and density imaging parameters may help for the evaluation of epileptogenic tubers in tuberous sclerosis complex patients
ObjectivesTo investigate the usefulness of neurite orientation dispersion and density imaging (NODDI) in evaluating cortical tubers, especially...
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Deep learning-based automated lesion segmentation on pediatric focal cortical dysplasia II preoperative MRI: a reliable approach
ObjectivesFocal cortical dysplasia (FCD) represents one of the most common causes of refractory epilepsy in children. Deep learning demonstrates...
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The impact of referring patients with drug-resistant focal epilepsy to an epilepsy center for presurgical diagnosis
BackgroundEpilepsy surgery is an established treatment for drug-resistant focal epilepsy (DRFE) that results in seizure freedom in about 60% of...
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Breath-Hold-Triggered BOLD fMRI in Drug-Resistant Nonlesional Focal Epilepsy—A Pilot Study
PurposeIndividuals with drug-resistant epilepsy may benefit from epilepsy surgery. In nonlesional cases, where no epileptogenic lesion can be...
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The efficacy of short acquisition time using 18F-FDG total-body PET/CT for the identification of pediatric epileptic foci
Background18 F-FDG positron emission tomography (PET) plays a crucial part in the evaluation for pediatric epileptic patients prior to therapy....
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Recovery of glymphatic system function in patients with temporal lobe epilepsy after surgery
ObjectivesTo investigate the recovery of human glymphatic system (GS) function in patients with temporal lobe epilepsy (TLE) after successful...
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Arterial spin-labelling and magnetic resonance spectroscopy as imaging biomarkers for detection of epileptogenic zone in non-lesional focal impaired awareness epilepsy
BackgroundThe proper identification of an epileptic focus is a pivotal diagnostic issue; particularly in non-lesional focal impaired awareness...
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First seizure in elderly patients: Need to treat? Evidence from a retrospective study
BackgroundThe risk of seizure recurrence after a first unprovoked epileptic seizure is reported to be approximately 40%. Little is known about the...
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Protocol of a prospective multicenter randomized controlled trial of robot-assisted stereotactic lesioning in the treatment of focal drug-resistant epilepsy
BackgroundThis protocol describes the design of a multicenter randomized controlled trial of robot-assisted stereotactic lesioning versus...
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Study protocol: value of 7-T MRI with prospective motion correction and postprocessing for patients with nonlesional epilepsy
The diagnostic yield of magnetic resonance imaging (MRI) postprocessing using 7‑T data for patients with nonlesional epilepsy has been rarely...
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Polymorphous low-grade neuroepithelial tumour of young (PLNTY): the new kid on the block
IntroductionPolymorphous low grade neuroepithelial tumor of the young (PLNTY) is a newly described epileptogenic tumor first reported by Jason. T....
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