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Investigating the cut-off values of captopril challenge test for primary aldosteronism using the novel chemiluminescent enzyme immunoassay method: a retrospective cohort study
The measurement evolution enabled more accurate evaluation of aldosterone production in hypertensive patients. However, the cut-off values for novel...
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New chemiluminescent enzyme immunoassay for quantitative measurement of Mac-2 binding protein glycosylation isomer in chronic liver disease
BackgroundThis study aimed to evaluate the quantitative measurement of Mac-2 binding protein glycosylation isomer (M2BPGi) levels using the new...
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An automated fluorescent immunoassay for on-site screening of AFM1 in raw milk at the ppt level
In the dairy industry, the quality of raw milk as it is collected from dairy farmers must be strictly ensured. Therefore, when on-site screening...
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Development and validation of a respiratory syncytial virus multiplex immunoassay
PurposeRespiratory syncytial virus (RSV) is one of the leading causes of severe respiratory disease in infants and adults. While vaccines and...
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Clinical performance of a novel chemiluminescent enzyme immunoassay for FGF23
IntroductionMeasurement of fibroblast growth factor 23 (FGF23) has been reported to be clinically useful for the differential diagnosis of chronic...
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Preparation of a highly specific and sensitive monoclonal antibody against tilmicosin and its application in lateral flow immunoassay
To reduce the false positive results caused by cross reactivity of the antibodies with other structural analogues, it is crucial to prepare a high...
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Comparison of fluorescent immunoassay (FIA) and electrochemiluminescence immunoassay (ECLIA) for the measurement of serum TSH in congenital hypothyroid screening
Delayed management of congenital hypothyroidism (CH) leads to permanent disability. The screening program of CH is, therefore, important. This study...
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Hapten design to prepare monoclonal antibodies and establishment of immunoassay for direct screening of oxamichydrazide in chicken, the metabolite of nifuraldezone
In this study, two novel haptens of oxamichydrazide (OXZ), the metabolite of nifuraldezone, were designed and synthesized by derivatization with...
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Novel triplex nucleic acid lateral flow immunoassay for rapid detection of Nipah virus, Middle East respiratory syndrome coronavirus and Reston ebolavirus
We report the development of a triplex nucleic acid lateral flow immunoassay (NALFIA) for the detection of the genomes of Nipah virus (NiV), Middle...
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Determination of cortisol cut-off limits and steroid dynamics in the ACTH stimulation test: a comparative analysis using Roche Elecsys Cortisol II immunoassay and LC-MS/MS
PurposeMeasurement of cortisol concentrations is method dependent. The study aimed to establish assay-specific cut-off limits for cortisol after...
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Automated electrochemiluminescence immunoassay for serum PlGF levels in women with singleton pregnancy at 9–13 weeks of gestation predicts preterm preeclampsia: a retrospective cohort study
Our aims were to obtain the gestational-age-specific median of common logarithmic placental growth factor (PlGF) values in the first trimester in...
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Clinical Application of Antibody Immunity Against SARS-CoV-2: Comprehensive Review on Immunoassay and Immunotherapy
The current COVID-19 global pandemic poses immense challenges to global health, largely due to the difficulty to detect infection in the early stages...
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Comparison of diagnostic efficiency of detecting IgG and IgE with immunoassay method in diagnosing ABPA: a meta-analysis
BackgroundHitherto, the bulk of diagnostic criteria regards Aspergillus -specific immunoglobulin E as a key item, and regard IgG as an auxiliary...
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Multicenter Evaluation of a Fully Automated High-Throughput SARS-CoV-2 Antigen Immunoassay
IntroductionMolecular testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to suffer from delays and shortages. Antigen...
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Multicentre Performance Evaluation of the Elecsys Anti-SARS-CoV-2 Immunoassay as an Aid in Determining Previous Exposure to SARS-CoV-2
IntroductionWe performed a multicentre evaluation of the Elecsys ® Anti-SARS-CoV-2 immunoassay (Roche Diagnostics), an assay utilising a recombinant...
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Hepatocellular carcinoma diagnosis using a novel electrochemiluminescence immunoassay targeting serum IgM-free AIM
BackgroundRecent increases in the number of patients with non-alcoholic steatohepatitis (NASH) warrant the identification of biomarkers for early...
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Development of a chromatographic lateral flow immunoassay for detection of African swine fever virus antigen in blood
African swine fever (ASF) is a highly lethal disease of domestic and wild swine caused by African swine fever virus (ASFV). The disease currently...
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Development of an accurate lateral flow immunoassay for PEDV detection in swine fecal samples with a filter pad design
Porcine epidemic diarrhea virus (PEDV), as the main causative pathogen of viral diarrhea in pigs, has been reported to result in high morbidity and...
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Development of a europium nanoparticles lateral flow immunoassay for NGAL detection in urine and diagnosis of acute kidney injury
BackgroundAKI is related to severe adverse outcomes and mortality with Coronavirus Disease 2019 (COVID-19) patients, that early diagnosed and...
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Oxidative Stress Enzyme as Markers in Oral Potentially Malignant Disorders and Oral Squamous Cell Carcinoma Patients
Oxidative stress is a recognized factor that poses a significant risk for the development of Oral Squamous Cell Carcinoma (OSCC) and Oral Submucous...