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Ovarian aging: energy metabolism of oocytes
In women who are getting older, the quantity and quality of their follicles or oocytes and decline. This is characterized by decreased ovarian...
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Global Energy Metabolism Deficit in Alzheimer Disease Brain
BackgroundThe understanding of Alzheimer’s disease (AD) has been dominated by the amyloid hypothesis. However, therapies targeting beta-amyloid have...
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Sex Differences in Energy Metabolism: A Female-Oriented Discussion
The purpose of this review is to delineate aspects of energy metabolism at rest and during exercise that may be subject to sex differences and the...
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Novel Insights into Osteoclast Energy Metabolism
Purpose of ReviewOsteoclasts are crucial for the dynamic remodeling of bone as they resorb old and damaged bone, making space for new bone. Metabolic...
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Energy metabolism: a new target for gastric cancer treatment
Gastric cancer is the fifth most common malignancy worldwide having the fourth highest mortality rate. Energy metabolism is key and closely linked to...
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From Energy Metabolic Change to Precision Therapy: a Holistic View of Energy Metabolism in Heart Failure
Heart failure (HF) is a complex and multifactorial disease that affects millions of people worldwide. It is characterized by metabolic disturbances...
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Targeting PDK2 rescues stress-induced impaired brain energy metabolism
Depression is a mental illness frequently accompanied by disordered energy metabolism. A dysregulated hypothalamus pituitary adrenal axis response...
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Effects of antipsychotic drugs on energy metabolism
Schizophrenia (SCZ) is a complex neuropsychiatric disorder associated with altered bioenergetic pathways and mitochondrial dysfunction. Antipsychotic...
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High-energy diet modify rumen microbial composition and microbial energy metabolism pattern in fattening sheep
Higher dietary energy is often used to achieve better animal performance in mutton sheep production. Notably, changing the diet formula affects rumen...
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**nbao Pill ameliorates heart failure via regulating the SGLT1/AMPK/PPARα axis to improve myocardial fatty acid energy metabolism
BackgroundHeart failure (HF) is characterized by a disorder of cardiomyocyte energy metabolism. **nbao Pill (XBW), a traditional Chinese medicine...
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Magnetic Resonance Spectroscopy Studies of Brain Energy Metabolism in Schizophrenia: Progression from Prodrome to Chronic Psychosis
Purpose of ReviewSchizophrenia (SZ) is a debilitating mental illness; existing treatments are partially effective and associated with significant...
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Bazi Bushen ameliorates age-related energy metabolism dysregulation by targeting the IL-17/TNF inflammatory pathway associated with SASP
BackgroundChronic inflammation and metabolic dysfunction are key features of systemic aging, closely associated with the development and progression...
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Altered Energy Metabolism, Mitochondrial Dysfunction, and Redox Imbalance Influencing Reproductive Performance in Granulosa Cells and Oocyte During Aging
Female fertility decreases during aging. The development of effective therapeutic strategies to address the age-related decline in oocyte quality and...
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Sex differences in energy metabolism: natural selection, mechanisms and consequences
Metabolic homeostasis operates differently in men and women. This sex asymmetry is the result of evolutionary adaptations that enable women to resist...
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Integrative analysis reveals that SLC38A1 promotes hepatocellular carcinoma development via PI3K/AKT/mTOR signaling via glutamine mediated energy metabolism
Although hepatocellular carcinoma (HCC) is rather frequent, little is known about the molecular pathways underlying its development, progression, and...
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Changes of energy metabolism in failing heart and its regulation by SIRT3
Heart failure (HF) is the leading cause of hospitalization in elderly patients and a disease with extremely high morbidity and mortality rate...
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Monomethyl Phthalate Causes Early Embryo Development Delay, Apoptosis, and Energy Metabolism Disruptions Through Inducing Redox Imbalance
Phthalates are a class of environmental endocrine disrupting chemicals which can cause reproductive system damages. However, data about reproductive...
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Causal effect of blood osteocalcin on the risk of Alzheimer’s disease and the mediating role of energy metabolism
Growing evidence suggests an association between osteocalcin (OCN), a peptide derived from bone and involved in regulating glucose and lipid...
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MCT4-dependent lactate transport: a novel mechanism for cardiac energy metabolism injury and inflammation in type 2 diabetes mellitus
Diabetic cardiomyopathy (DCM) is a major contributor to mortality in diabetic patients, characterized by a multifaceted pathogenesis and limited...
