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High resolution dynamic ultrasound atlas of embryonic and fetal development of the common marmoset
PurposeThe common marmoset ( Callithrix jacchus ) provides an ideal model to study early development of primates, and an in viv o platform to validate...
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Embryonic mouse medial neocortex as a model system for studying the radial glial scaffold in fetal human neocortex
Neocortex is the evolutionarily newest region in the brain, and is a structure with diversified size and morphology among mammalian species. Humans...
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Fetal Tricuspid Valve Agenesis/Atresia: Testing Predictions of the Embryonic Etiology
Tricuspid valve agenesis/atresia (TVA) is a congenital cardiac malformation where the tricuspid valve is not formed. It is hypothesized that TVA...
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Maternal lipid profile in pregnancy and embryonic size: a population-based prospective cohort study
BackgroundLipids are crucial for fetal growth and development. Maternal lipid concentrations are associated with fetal growth in the second and third...
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Maternal cardiovascular disorders before and during pregnancy and offspring cardiovascular risk across the life course
Obesity, hypertension, type 2 diabetes mellitus and dyslipidaemia are highly prevalent among women of reproductive age and contribute to...
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A 3D atlas of the human develo** pancreas to explore progenitor proliferation and differentiation
Aims/hypothesisRodent pancreas development has been described in great detail. On the other hand, there are still gaps in our understanding of the...
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Development and function of the fetal adrenal
The adrenal cortex undergoes multiple structural and functional rearrangements to satisfy the systemic needs for steroids during fetal life,...
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Direct embryonic biopsy with transcervical embryoscopy is an effective method for karyoty** and morphology assessment in miscarriages
PurposeThe main purpose of this study is to compare the validity of transcervical embryoscopy method with standard uterine evacuation method in...
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Maternal age, history of miscarriage, and embryonic/fetal size are associated with cytogenetic results of spontaneous early miscarriages
PurposeTo clarify the associations of the maternal age, history of miscarriage, and embryonic/fetal size at miscarriage with the frequencies and...
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Fetal cannabidiol (CBD) exposure alters thermal pain sensitivity, problem-solving, and prefrontal cortex excitability
Thousands of people suffer from nausea with pregnancy each year. Nausea can be alleviated with cannabidiol (CBD), a primary component of cannabis...
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MiR-124-3p negatively impacts embryo implantation via suppressing uterine receptivity formation and embryo development
During embryo implantation, blastocyst interacts with the receptivity endometrium and the endometrial epithelium secretes nurturing fluid to support...
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Safety of embryo cryopreservation: insights from mid-term placental transcriptional changes
BackgroundIn recent years, with benefits from the continuous improvement of clinical technology and the advantage of fertility preservation, the...
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Does growth hormone supplementation of in vitro fertilization/intracytoplasmic sperm injection improve cumulative live birth rates in women with poor embryonic development in the previous cycle?
BackgroundGrowth hormone (GH) has been proposed as an adjunct in in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) cycles,...
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Vein of Galen aneurysmal malformation: does size affect outcome?
PurposeTo validate a semiautomated method for segmenting vein of Galen aneurysmal malformations (VGAM) and to assess the relationship between VGAM...
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Wdr5 is essential for fetal erythropoiesis and hematopoiesis
WDR5 is a highly conserved protein that performs multiple scaffolding functions in the context of chromatin. However, efforts to understand the...
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Vascular ring: prenatal diagnosis and prognostic management based on sequential cross-sectional scanning by ultrasound
BackgroundIn terms of embryonic origin, vascular ring is a congenital anomaly in which the aortic arch and its branches completely or incompletely...
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Prenatal diagnosis and mRNA profiles of fetal tetralogy of Fallot
Tetralogy of fallot (TOF) in the fetus is a typical congential heart disease that occurs during the early embryonic period, being characterized by...
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Fetal anemia and elevated hepcidin in a mouse model of fetal alcohol spectrum disorder
IntroductionPrenatal alcohol exposure (PAE) impairs offspring growth and cognition, and this is worsened by concurrent iron deficiency. Alcohol...
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Dysregulation of CITED2 in abnormal lung development in the nitrofen rat model
PurposeCITED2 both modulates lung, heart and diaphragm development. The role of CITED2 in the pathogenesis of congenital diaphragmatic hernia (CDH)...