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Determinants of Embryo Implantation: Roles of the Endometrium and Embryo in Implantation Success
Both uterine endometrium and embryo contribute to implantation success. However, their relative role in the implantation success is still a matter...
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MiR-124-3p negatively impacts embryo implantation via suppressing uterine receptivity formation and embryo development
During embryo implantation, blastocyst interacts with the receptivity endometrium and the endometrial epithelium secretes nurturing fluid to support...
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Differential expression of tsRNAs and miRNAs in embryo culture medium: potential impact on embryo implantation
PurposeCan small RNA derived from embryos in conditioned embryo culture medium (ECM) influence embryo implantation?
MethodsWe employed small RNA...
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Prediction model for day 3 embryo implantation potential based on metabolites in spent embryo culture medium
BackgroundMetabolites in spent embryo culture medium correlate with the embryo’s viability. However, there is no widely accepted method using...
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Embryo Transfer Strategies for Women with Recurrent Implantation Failure During the Frozen-thawed Embryo Transfer Cycles: Sequential Embryo Transfer or Double-blastocyst Transfer?
ObjectiveBoth sequential embryo transfer (SeET) and double-blastocyst transfer (DBT) can serve as embryo transfer strategies for women with recurrent...
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Sequential embryo transfer combined with intrauterine perfusion improved pregnancy outcomes in patients with recurrent implantation failure
ObjectiveTo compare the application of sequential embryo transfer, cleavage embryo transfer, and blastocyst transfer combined with intrauterine...
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KRT18 regulates trophoblast cell migration and invasion which are essential for embryo implantation
Female infertility is a worldwide concern that impacts the quality of life and well-being of affected couples. Failure of embryo implantation is a...
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Progress on the Role of Estrogen and Progesterone Signaling in Mouse Embryo Implantation and Decidualization
Embryo implantation and decidualization are key steps in establishing a successful pregnancy. Defects in embryo implantation and decidualization can...
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One center experience with a personalized frozen-thawed embryo transfer in patients with recurrent implantation failure
PurposeDisplaced endometrial receptivity has been discussed as a possible cause of recurrent implantation failure in patients undergoing assisted...
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Efficacy of endometrial receptivity testing for recurrent implantation failure in patients with euploid embryo transfers: study protocol for a randomized controlled trial
BackgroundEmbryo implantation remains a critical barrier in assisted reproductive technologies. One of the main causes of unsuccessful embryo...
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Combined oral antibiotics and intrauterine perfusion can improve in vitro fertilization and embryo transfer pregnancy outcomes in patients with chronic endometritis and repeated embryo implantation failure
BackgroundThe aim of this retrospective study was to investigate whether oral antibiotics (doxycycline and metronidazole) combined with intrauterine...
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Combining Machine Learning with Metabolomic and Embryologic Data Improves Embryo Implantation Prediction
This study investigated whether combining metabolomic and embryologic data with machine learning (ML) models improve the prediction of embryo...
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Exploring Natural Killer Cell Testing in Embryo Implantation and Reproductive Failure: An Overview of Techniques and Controversies
The blastocyst nidation is the most crucial stage to a successful pregnancy, as the white cells work to promote a favorable endometrial...
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Acupuncture combined with gonadotropin-releasing hormone agonists improves endometrial receptivity and pregnancy outcome in patients with recurrent implantation failure of in vitro fertilization-embryo transfer
ObjectiveGonadotropin-releasing hormone agonists (GnRHa), combined with other auxiliary treatments, can improve pregnancy outcomes in in vitro...
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Maternal hypercholesterolemia would increase the incidence of embryo aneuploidy in couples with recurrent implantation failure
BackgroundThe association of dyslipidemia with embryo development and pregnancy outcomes is largely unknown, especially in unexplained recurrent...
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Single Cell Proteomics Profiling Reveals That Embryo-Secreted TNF-α Plays a Critical Role During Embryo Implantation to the Endometrium
It has been long-known that endometrium-secreted cytokines play a critical role during embryo implantation. However, whether cytokines secreted from...
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The predictive value of uterine artery Doppler in the success rate of pregnancy from the first frozen embryo transfer during the implantation window
BackgroundWorldwide, frozen embryo transfer (FET) has become a new strategy for the treatment of infertility. The success of FET is closely related...
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Association of embryo aneuploidy and sperm DNA damage in unexplained recurrent implantation failure patients under NGS-based PGT-A cycles
PurposeRecurrent implantation failure (RIF) is one of the most common conditions affecting In Vitro Fertilization (IVF)/Intracytoplasmic sperm...
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MicroRNA signatures in plasma and plasma exosome during window of implantation for implantation failure following in-vitro fertilization and embryo transfer
BackgroundMicroRNAs (miRNAs) are small, non-coding RNAs that are dysregulated in many diseases and can act as biomarkers. Although well-studied in...
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Metabolomics analysis of serum metabolites during endometrial transformation: association with recurrent implantation failure in hormonal replacement therapy-frozen embryo transfers cycles
PurposeThe purpose of this study was to investigate alterations in serum metabolites during endometrial transformation and possible associations...
