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Spatial profiling of cancer-associated fibroblasts of sporadic early onset colon cancer microenvironment
The incidence of sporadic early-onset colon cancer (EOCC) has increased worldwide. The molecular mechanisms in the tumor and the tumor...
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Impact of tumor size on overall survival and cancer-specific survival of early-onset colon and rectal cancer: a retrospective cohort study
PurposeThis study aimed to investigate the impact of tumor size on survival in early-onset colon and rectal cancer.
MethodsEarly-onset colon and...
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Combined endoscopic and laparoscopic surgery (CELS) for early colon cancer in high-risk patients
BackgroundLocal excision of early colon cancers could be an option in selected patients with high risk of complications and no sign of lymph node...
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Predicting survival and prognosis in early-onset locally advanced colon cancer: a retrospective observational study
ObjectiveTo predict cancer-specific survival, a refined nomogram model and brand-new risk-stratifying system were established to classify the risk...
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Prognostic factors in pulmonary metastases resection from colorectal cancer: impact of right-sided colon cancer and early recurrence
ObjectiveThis retrospective cohort study aimed to explore the surgical outcomes and prognostic factors of resection of pulmonary metastases (PM) from...
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Is a less-intensive follow-up for colon cancer in early stages reasonable?
PurposePatients with colon cancer are usually included in an intensive 5-year surveillance protocol after curative resection, independent of the...
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Clinical trials of neoadjuvant immune checkpoint inhibitors for early-stage operable colon and rectal cancer
BackgroundImmune checkpoint inhibitors (ICI) have become first-line treatment for metastatic colorectal cancer (CRC) with deficient mismatch repair...
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Early-stage sigmoid colon cancer resection followed by liver metastasis recurrence 1 year later and mesenteric recurrence more than 5 years later: a case report
BackgroundEarly-stage colorectal cancer (CRC) is often treated endoscopically, but additional surgical resection may be considered depending on...
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Design and evaluation of a colon cancer mobile application
BackgroundColorectal cancer (CRC) is the third leading cause of cancer and the second cause of cancer-related deaths in the world. Despite the...
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Use of Circulating Tumor DNA to Guide Decision-making in Adjuvant Colon Cancer
Purpose of ReviewThe use of circulating tumor DNA (ctDNA) assays to guide clinical decision-making in early-stage colon cancer is an area of rapidly...
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Development and validation of prognostic nomograms for early-onset colon cancer in different tumor locations: a population-based study
ObjectiveThe prevalence of early-onset colon cancer (EOCC) among individuals below the age of 50 has shown a marked upward trend in recent years. The...
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Robot-assisted fluorescent sentinel lymph node identification in early-stage colon cancer
BackgroundPatients with cT1-2 colon cancer (CC) have a 10–20% risk of lymph node metastases. Sentinel lymph node identification (SLNi) could improve...
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Early recurrence after complete mesocolic excision for right-sided colon cancer with D3 lymphadenectomy: pattern, risk factors, prognostic impact, and individualized follow-up
The definition of early recurrence (ER) for right-sided colon cancer patients after complete mesocolic excision (CME) with D3 lymphadenectomy remains...
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Ascending colon cancer metastasized to the right testicle: a case report
BackgroundTesticular metastasis from malignant solid tumors is extremely rare. It is usually found by chance during autopsy or pathological...
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Establishment and validation of a prognostic nomogram for patients with early-onset stage I–II colon cancer
BackgroundThe aims of this study were to establish and validate a nomogram model for predicting the survival of patients with early-onset stage I–II...
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Preoperative Strategies for Locally Advanced Colon Cancer
Neoadjuvant chemotherapy is safe for patients with locally advanced colon cancer (LACC). The FOxTROT trial demonstrated a reduction in residual and...
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Construction of the survival nomograms for colon cancer patients of different ages based on the SEER database
IntroductionThree nomograms for predicting the outcomes of early- and late-onset colon cancer (COCA) among patients not stratified by age were...
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Radiologic T staging of colon cancer: renewed interest for clinical practice
Radiologic imaging, especially MRI, has long been the mainstay for rectal cancer staging and patient selection for neoadjuvant therapy prior to...
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Lymph Node Metastases and Associated Recurrence-Free Survival in Microsatellite Stable and Unstable Colon Cancer
BackgroundIn contrast to microsatellite stable (MSS) colon cancer, predictors of lymph node metastases and their association with recurrence are not...
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The Effect of RAS/BRAF Mutation Status on Prognosis and Relapse Pattern in Early Stage Colon Cancers
PurposeIt is known that the RAS and BRAF mutations are predictive for targeted therapies in treating metastatic colon cancer and negatively affect...
