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Identification of kynurenine and quinolinic acid as promising serum biomarkers for drug-induced interstitial lung diseases
BackgroundDrug-induced interstitial lung disease (DILD) is a lung injury caused by various types of drugs and is a serious problem in both clinical...
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Analysis of drug-induced interstitial lung disease caused by herbal medicine using the Japanese Adverse Drug Event Report database
BackgroundDrug-induced interstitial lung disease (DIILD) is a severe adverse event leading to morbidity and mortality. This study evaluated the...
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Drug-induced interstitial lung disease caused by olaparib: three case reports and review of the Japanese Adverse Drug Event Report database and literature
BackgroundOlaparib, a poly (ADP-ribose) polymerase (PARP) inhibitor, has demonstrated effectiveness in treating ovarian, breast, and other cancers,...
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Expert Consensus on the Diagnosis and Treatment of Anticancer Drug-Induced Interstitial Lung Disease
Drug-induced interstitial lung disease (DILD) is the most common pulmonary adverse event of anticancer drugs. In recent years, the incidence of...
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Advances in multimodal imaging of lung injury
Lung injury is caused by various physical and chemical damages that lead to the destruction of the structural integrity or dysfunction of the lungs,...
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Vitamin D3 improved hypoxia-induced lung injury by inhibiting the complement and coagulation cascade and autophagy pathway
BackgroundPulmonary metabolic dysfunction can cause lung tissue injury. There is still no ideal drug to protect against...
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Differential diagnosis of infectious diseases, drug-induced lung injury, and pulmonary infiltration due to underlying malignancy in patients with hematological malignancy using HRCT
PurposeTo differentiate among infectious diseases, drug-induced lung injury (DILI) and pulmonary infiltration due to underlying malignancy (PIUM)...
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Identification of MRI features associated with injury type, severity, and prognosis in drug-induced liver injury
ObjectivesTo identify magnetic resonance imaging (MRI) features associated with injury type, severity, and liver transplantation (LT)/liver-related...
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Drug-induced interstitial lung disease due to over-the-counter cold medicine taken daily for 25 years: a case report
IntroductionWe report a rare case of drug-induced interstitial lung disease due to over-the-counter cold medicine taken daily for 25 years to clear...
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High-intensity intermittent training ameliorates methotrexate-induced acute lung injury
Inflammation and oxidative stress are recognized as two primary causes of lung damage induced by methotrexate, a drug used in the treatment of cancer...
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Interpretable machine learning in predicting drug-induced liver injury among tuberculosis patients: model development and validation study
BackgroundThe objective of this research was to create and validate an interpretable prediction model for drug-induced liver injury (DILI) during...
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Cyasterone ameliorates sepsis-related acute lung injury via AKT (Ser473)/GSK3β (Ser9)/Nrf2 pathway
BackgroundAcute lung injury (ALI) is a severe disease that can lead to acute respiratory distress syndrome (ARDS), characterized by intractable...
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Protective Effects of Danmu Extract Syrup on Acute Lung Injury Induced by Lipopolysaccharide in Mice through Endothelial Barrier Repair
ObjectiveTo investigate the effects of Danmu Extract Syrup (DMS) on lipopolysaccharide (LPS)-induced acute lung injury (ALI) in mice and explore the...
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Angiotensin Receptor Blockers and the Risk of Suspected Drug-Induced Liver Injury: A Retrospective Cohort Study Using Electronic Health Record-Based Common Data Model in South Korea
IntroductionAngiotensin receptor blockers are widely used antihypertensive drugs in South Korea. In 2021, the Korea Ministry of Food and Drug Safety...
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Blocking RAGE expression after injury reduces inflammation in mouse model of acute lung injury
BackgroundReceptor for Advanced Glycated Endproducts (RAGE) plays a major role in the inflammatory response to infectious and toxin induced acute...
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Activation of NLRP3 inflammasome in lung epithelial cells triggers radiation-induced lung injury
BackgroundRadiation-induced lung injury (RILI) is the most common and serious complication of chest radiotherapy. However, reported radioprotective...
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The efficacy of extracellular vesicles for acute lung injury in preclinical animal models: a meta-analysis
BackgroundWith the increasing research on extracellular vesicles (EVs), EVs have received widespread attention as biodiagnostic markers and...
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Metformin attenuates lung ischemia-reperfusion injury and necroptosis through AMPK pathway in type 2 diabetic recipient rats
BackgroundDiabetes mellitus (DM) can aggravate lung ischemia-reperfusion (I/R) injury and is a significant risk factor for recipient mortality after...
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Inhibition of fatty acid synthase protects obese mice from acute lung injury via ameliorating lung endothelial dysfunction
BackgroundObesity has been identified as a risk factor for acute lung injury/acute respiratory distress syndrome (ALI/ARDS). However, the underlying...
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Bosutinib-induced lung injury: a report of two cases and literature review
The prognosis of patients with chronic myeloid leukemia (CML) has improved dramatically since the development of tyrosine kinase inhibitors (TKIs)....
