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Tolerability and efficacy of a reduced dose adenosine stress cardiac magnetic resonance protocol under general anesthesia in infants and children
BackgroundIntravenous adenosine induces pharmacological stress by causing vasodilatation and thus carries the risk of severe hypotension when...
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Diagnosis and Management of Fetal Ductus Arteriosus Constriction
The ductus arteriosus is an important structure in the fetal circulation. It connects the pulmonary artery to the arch of the aorta distal to the...
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The Effects of Aspirin dose in Children with Congenital and Acquired Heart Disease. Results from the Paediatric Study of Aspirin Efficacy using Diagnostic and Monitoring Tools (PAED-M)
The optimal dose of aspirin required in children with congenital and acquired heart disease is not known. The primary aim of this prospective...
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Geotemporospatial and causal inference epidemiological analysis of US survey and overview of cannabis, cannabidiol and cannabinoid genotoxicity in relation to congenital anomalies 2001–2015
BackgroundCannabinoids including cannabidiol have recognized genotoxic activities but their significance has not been studied broadly...
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Aspirin Responsiveness in a Cohort of Pediatric Patients with Right Ventricle to Pulmonary Artery Conduits and Transcatheter Valve Replacement Systems
The aim of this study was to determine the rate of aspirin responsiveness in a cohort of pediatric patients with in situ xenograft valved right...
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Ectopic Atrial Tachycardia in Infants Following Congenital Heart Disease Surgery
Although ectopic atrial tachycardia (EAT) is common following surgery for congenital heart disease (CHD), there are limited data regarding this...
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Sildenafil for congenital heart diseases induced pulmonary hypertension, a meta-analysis of randomized controlled trials
BackgroundSildenafil was first prescribed for angina pectoris and then for erectile dysfunction from its effects on vascular smooth muscle relaxation...
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Effect of maternal pregestational diabetes mellitus on congenital heart diseases
BackgroundThe increasing population of diabetes mellitus in adolescent girls and women of childbearing age contributes to a large number of...
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Continuous Prostanoid Initiation in Severe Pulmonary Hypertension in the Pediatric Cardiac Intensive Care Unit
ObjectiveLimited data exists regarding prostanoid (PGI2) use in critically ill patients with pulmonary hypertension. (PH) in the pediatric cardiac...
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Multidetector computed tomography for patients with congenital heart disease: a multi-center registry from Africa and Middle East; patients’ characteristics and procedural safety
BackgroundWe aimed to establish a clinical registry for patients with congenital heart disease who referred to multidetector computed tomography in...
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Biomarkers for isolated congenital heart disease based on maternal amniotic fluid metabolomics analysis
IntroductionCongenital heart disease (CHD) is one of the most prevalent birth defects in the world. The pathogenesis of CHD is complex and unclear....
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Intermittent intravenous paracetamol versus continuous morphine in infants undergoing cardiothoracic surgery: a multi-center randomized controlled trial
BackgroundTo determine whether intermittent intravenous (IV) paracetamol as primary analgesic would significantly reduce morphine consumption in...
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Optimizing neonatal cardiac imaging (magnetic resonance/computed tomography)
Magnetic resonance imaging (MRI) and CT perform an important role in the evaluation of neonates with congenital heart disease (CHD) when...
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CeRebrUm and CardIac Protection with ALlopurinol in Neonates with Critical Congenital Heart Disease Requiring Cardiac Surgery with Cardiopulmonary Bypass (CRUCIAL): study protocol of a phase III, randomized, quadruple-blinded, placebo-controlled, Dutch multicenter trial
BackgroundNeonates with critical congenital heart disease (CCHD) undergoing cardiac surgery with cardiopulmonary bypass (CPB) are at risk of brain...
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Effect of Carnitine Supplementation in Pediatric Patients with Left Ventricular Dysfunction
Carnitine is an essential amino acid involved in transporting fatty acids across the mitochondrial membrane. Fatty acids are a primary source of...
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Understanding the Genetic and Non-genetic Interconnections in the Aetiology of Isolated Congenital Heart Disease: An Updated Review: Part 1
Purpose of ReviewCongenital heart disease (CHD) is the most frequently occurring birth defect. Majority of the earlier reviews focussed on the...
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The Efficacy of Corticosteroids, NSAIDs, and Colchicine in the Treatment of Pediatric Postoperative Pericardial Effusion
The objective of this study is to investigate and compare the efficacy of corticosteroids, NSAIDs, and colchicine in treating postoperative...
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High-resolution three‑dimensional contrast‑enhanced magnetic resonance venography in children: comparison of gadofosveset trisodium with ferumoxytol
BackgroundGadofosveset is a gadolinium-based blood pool contrast agent that was approved by the United States Food and Drug Administration in 2008....
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Gravity-assisted continuous flow peritoneal dialysis technique use in acute kidney injury in children: a randomized, crossover clinical trial
BackgroundOur previously demonstrated continuous flow peritoneal dialysis (CFPD) technique in children with acute kidney injury (AKI), although...
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Indonesian Study: Triiodothyronine for Infants Less than 5 Months Undergoing Cardiopulmonary Bypass
This study evaluates the efficacy and safety of oral triiodothyronine on time to extubation for infants less than 5 months undergoing heart surgery...
