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Drug Burden Index in Older Adults with Psychiatric Illnesses: A Cross-Sectional Study
BackgroundMedications with anticholinergic and/or sedative properties are commonly used in the management of psychiatric illnesses. The burden of...
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Association of drug burden index with delirium in community-dwelling older adults with dementia: a longitudinal observational study
BackgroundThe Drug Burden Index (DBI) is a validated tool for assessing the dose-dependent cumulative exposure to sedative and anticholinergic...
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Impact of a Comprehensive Intervention Bundle Including the Drug Burden Index on Deprescribing Anticholinergic and Sedative Drugs in Older Acute Inpatients: A Non-randomised Controlled Before-and-After Pilot Study
IntroductionImplementation of the Drug Burden Index (DBI) as a risk assessment tool in clinical practice may facilitate deprescribing.
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Burden of drug use disorders in the United States from 1990 to 2021 and its projection until 2035: results from the GBD study
BackgroundDrug use disorders (DUDs) have emerged as one of the most significant public health crises, exerting a substantial influence on both...
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Disentangling drug contributions: anticholinergic burden in older adults linked to individual medications: a cross-sectional population-based study
BackgroundMedications with potent anticholinergic properties have well-documented adverse effects. A high cumulative anticholinergic burden may arise...
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Global and regional quality of care index for prostate cancer: an analysis from the Global Burden of Disease study 1990–2019
BackgroundProstate cancer (PCa) is one of the most prevalent cancers worldwide, with a significant burden on societies and healthcare providers. We...
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Global burden of self-harm and interpersonal violence and influencing factors study 1990–2019: analysis of the global burden of disease study
IntroductionWidespread concern exists in today’s world regarding self-harm and interpersonal violence. This study to analyze the changes in temporal...
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Global, regional, and national quality of care index of cervical and ovarian cancer: a systematic analysis for the global burden of disease study 1990–2019
Background and objectiveCervical cancer is the most preventable and ovarian cancer is the most lethal gynecological cancer. However, in the world,...
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Global burden of diseases attributable to intimate partner violence: findings from the Global Burden of Disease Study 2019
PurposeOur study aims to evaluate the global burden of disease attributable to IPV from 1990 to 2019 at global, regional, national, and...
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Development of the Swedish anticholinergic burden scale (Swe-ABS)
BackgroundDrugs with anticholinergic properties are associated with cognitive adverse effects, especially in patients vulnerable to central...
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Anticholinergic Burden and Cognitive Impairment in Nursing Homes: A Comparison of Four Anticholinergic Scales
BackgroundMedications with anticholinergic effects are commonly used in nursing homes, and their cumulative effect is of particular concern for the...
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Global, regional, and national burden of asthma and its attributable risk factors from 1990 to 2019: a systematic analysis for the Global Burden of Disease Study 2019
BackgroundThe burden of asthma in terms of premature death or reduced quality of life remains a huge issue. It is of great importance to evaluate...
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Global burden of hip fracture: The Global Burden of Disease Study
SummaryThis study is the first to measure global burden of hip fracture in patients aged 55 years and older across 204 countries and territories from...
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Cumulative Anticholinergic Burden and its Predictors among Older Adults with Alzheimer’s Disease Initiating Cholinesterase Inhibitors
BackgroundCumulative anticholinergic burden refers to the cumulative effect of multiple medications with anticholinergic properties. However,...
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The relationship between dry eye disease and anticholinergic burden
PurposeAnticholinergic drugs are widely prescribed for many medical conditions. However, data on the association of anticholinergic burden with dry...
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Trends of the Global Burden of Disease Attributable to Cannabis Use Disorder in 204 Countries and Territories, 1990–2019: Results from the Disease Burden Study 2019
Cannabis is the fourth psychoactive substance to be legalized which are of far-reaching significance to the world. We analyzed data from the 2019...
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Clinical pharmacist-led assessment and management of anticholinergic burden and fall risk in geriatric patients
BackgroundThe aim of this study was to examine the risk of fall with the surrogate outcome of the Aachen Falls Prevention Scale and to assess the...
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The burden of Cardiovascular diseases in Jordan: a longitudinal analysis from the global burden of disease study, 1990–2019
BackgroundCardiovascular Disease (CVD) is the leading cause of mortality worldwide. While countries in the Arab world continue to lack public health...
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The burden of vision loss due to cataract in China: findings from the Global Burden of Disease Study 2019
ObjectiveTo provide a reference for future policy and measure formulation by conducting a detailed analysis of the burden of vision loss due to...
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Global trends in pharmacovigilance-related events: a 30-year analysis from the 2019 global burden of disease study
BackgroundEstablishing effective pharmacovigilance systems globally is challenging due to the need for comprehensive epidemiological data on...