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Noninvasive Neuromonitoring Modalities in Children Part I: Pupillometry, Near-Infrared Spectroscopy, and Transcranial Doppler Ultrasonography
BackgroundNoninvasive neuromonitoring in critically ill children includes multiple modalities that all intend to improve our understanding of acute...
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Effects of ephedrine and phenylephrine on cerebral oxygenation: observational prospective study using near-infrared time-resolved spectroscopy
It has been reported that cerebral oxygenation (ScO 2 ) measured by near infrared spectroscopy is maintained or increased by treatment with ephedrine,...
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Near-infrared spectroscopy monitoring of neonatal cerebrovascular reactivity: where are we now?
AbstractCerebrovascular reactivity defines the ability of the cerebral vasculature to regulate its resistance in response to both local and systemic...
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The clinical significance of renal resistance index (RRI) and renal oxygen saturation (RrSO2) in critically ill children with AKI: a prospective cohort study
ObjectiveThe purpose of this study was to look into the clinical significance of the renal resistance index (RRI) and renal oxygen saturation (RrSO2)...
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Advanced Neuromonitoring Modalities on the Horizon: Detection and Management of Acute Brain Injury in Children
Timely detection and monitoring of acute brain injury in children is essential to mitigate causes of injury and prevent secondary insults. Increasing...
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Perioperative Neuromonitoring in Children with Congenital Heart Disease
Although neonates and children with congenital heart disease are primarily hospitalized for cardiac and pulmonary diseases, they are also at an...
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EPR Monitoring of Oxygenation Levels in Tumors After Chlorophyllide-Based Photodynamic Therapy May Allow for Early Prediction of Treatment Outcome
PurposeMolecular oxygen, besides a photosensitizer and light of appropriate wavelength, is one of the three factors necessary for photodynamic...
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Early assessment of injury with optical markers in a piglet model of neonatal encephalopathy
BackgroundOpportunities for adjunct therapies with cooling in neonatal encephalopathy are imminent; however, robust biomarkers of early assessment...
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Usefulness of a finger-mounted tissue oximeter with near-infrared spectroscopy for evaluating the intestinal oxygenation and viability in rats
PurposeTo investigate the utility of the device for evaluating intestinal oxygenation and viability using an animal model.
MethodsSprague–Dawley...
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Saving babies and families from preventable harm: a review of the current state of fetoplacental monitoring and emerging opportunities
Neonatal outcomes have improved over the last decade following significant thrust in this area, but stillbirth, preterm birth and neonatal brain...
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Cortical Spreading Depolarization, Blood Flow, and Cognitive Outcomes in a Closed Head Injury Mouse Model of Traumatic Brain Injury
BackgroundCortical spreading depolarizations (CSDs) are associated with worse outcomes in many forms of acute brain injury, including traumatic brain...
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The Importance of Neuromonitoring in Non Brain Injured Patients
This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2022. Other selected articles can be...
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Effects of hemodynamic alterations and oxygen saturation on cerebral perfusion in congenital heart disease
BackgroundPatients with severe congenital heart disease (CHD) are at risk for neurodevelopmental impairment. An abnormal cerebral blood supply caused...
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Neuromonitoring after Pediatric Cardiac Arrest: Cerebral Physiology and Injury Stratification
BackgroundSignificant long-term neurologic disability occurs in survivors of pediatric cardiac arrest, primarily due to hypoxic-ischemic brain...
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The future of intensive care: the study of the microcirculation will help to guide our therapies
The goal of hemodynamic resuscitation is to optimize the microcirculation of organs to meet their oxygen and metabolic needs. Clinicians are...
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Clinical targeting of the cerebral oxygen cascade to improve brain oxygenation in patients with hypoxic–ischaemic brain injury after cardiac arrest
The cerebral oxygen cascade includes three key stages: (a) convective oxygen delivery representing the bulk flow of oxygen to the cerebral vascular...
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Quantification of dynamic cerebral autoregulation: welcome to the jungle!
PurposePatients with dysautonomia often experience symptoms such as dizziness, syncope, blurred vision and brain fog. Dynamic cerebral...
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Recipient bed perfusion as a predictor for postoperative complications in irradiated patients with microvascular free tissue transfer of the head and neck area: a clinical analysis of 191 microvascular free flaps
PurposeDespite microvascular free tissue transfer being the mainstay of care in the reconstruction of larger maxillofacial defects, a significant...
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Novel Modality of Endoluminal Anastomotic Integrity Assessment with Fluoroangiography After Left-sided Colorectal Resections
BackgroundSeveral methods have been described for the intraoperative evaluation of colorectal anastomotic integrity. Technological evolution has...
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A biobehavioral observational study to understand the multilevel determinants of cardiovascular health in Black women: the BLOOM Study protocol
BackgroundThe racial/ethnic and gender disparities in cardiovascular disease (CVD) morbidity and mortality in the United States are evident. Across...
