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Mode of transport, genetic susceptibility, and incidence of coronary heart disease
BackgroundCar use has been associated with higher risk of coronary heart disease (CHD). However, whether the associations of transport modes with CHD...
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Whole-exome sequencing analysis identifies novel variants associated with Kawasaki disease susceptibility
BackgroundKawasaki disease (KD) is an acute pediatric vasculitis affecting genetically susceptible infants and children. Although the pathogenesis of...
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The characteristic patterns of individual brain susceptibility networks underlie Alzheimer’s disease and white matter hyperintensity-related cognitive impairment
Excessive iron accumulation in the brain cortex increases the risk of cognitive deterioration. However, interregional relationships (defined as...
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Mendelian susceptibility to mycobacterial disease: an overview
BackgroundMycobacteria include ubiquitous species of varying virulence. However, environmental and individual-specific factors, particularly host...
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Alterations in subcortical magnetic susceptibility and disease-specific relationship with brain volume in major depressive disorder and schizophrenia
Quantitative susceptibility map** is a magnetic resonance imaging technique that measures brain tissues’ magnetic susceptibility, including iron...
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Genome-wide analyses in Lyme borreliosis: identification of a genetic variant associated with disease susceptibility and its immunological implications
BackgroundGenetic variation underly inter-individual variation in host immune responses to infectious diseases, and may affect susceptibility or the...
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Mendelian randomization analysis suggests no causal influence of gastroesophageal reflux disease on the susceptibility and prognosis of idiopathic pulmonary fibrosis
BackgroundThe relationship between gastroesophageal reflux disease (GERD) and the susceptibility as well as the prognosis of idiopathic pulmonary...
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Fetal cell microchimerism and susceptibility to COVID-19 disease in women
PurposeThe clinical outcome of COVID-19 disease is worse in males, and the reasons of this gender disparity are currently unclear, though evidences...
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Outcomes of adults with invasive meningococcal disease with reduced penicillin susceptibility in Auckland 2004–2017
PurposeThe purpose of this study was to assess the clinical outcomes of adults with invasive meningococcal disease (IMD) and to compare the outcomes...
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Erratum to: Digital Clock Drawing as an Alzheimer’s Disease Susceptibility Biomarker: Associations with Genetic Risk Score and APOE in Older Adults
The article ≪Digital Clock Drawing as an Alzheimer’s Disease Susceptibility Biomarker: Associations with Genetic Risk Score and APOE in Older...
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B-lymphocyte-activating factor is a potential biomarker associated with susceptibility to Graves’ disease in Iraqi women
BackgroundB-lymphocyte-activating factor (BAFF) is a cytokine involved in regulating the development and maturation of B lymphocyte and has been...
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Digital Clock Drawing as an Alzheimer’s Disease Susceptibility Biomarker: Associations with Genetic Risk Score and APOE in Older Adults
BackgroundAlzheimer’s disease (AD) is the leading cause of dementia in older adults, but most people are not diagnosed until significant neuronal...
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Knockdown the moyamoya disease susceptibility gene, RNF213, upregulates the expression of basic fibroblast growth factor and matrix metalloproteinase-9 in bone marrow derived mesenchymal stem cells
Moyamoya disease (MMD) is a chronic, progressive cerebrovascular occlusive disease. Ring finger protein 213 (RNF213) is a susceptibility gene of MMD....
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Multi-parametric radiomics of conventional T1 weighted and susceptibility-weighted imaging for differential diagnosis of idiopathic Parkinson’s disease and multiple system atrophy
ObjectivesThis study aims to investigate the potential of radiomics with multiple parameters from conventional T1 weighted imaging (T1WI) and...
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Combining quantitative susceptibility map** to radiomics in diagnosing Parkinson’s disease and assessing cognitive impairment
ObjectiveTo explore whether magnetic susceptibility value (MSV) and radiomics features of the nigrostriatal system could be used as imaging markers...
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Genetic susceptibility, screen-based sedentary activities and incidence of coronary heart disease
BackgroundWhether the associations of time spent in screen-based sedentary activities with CHD vary by genetic susceptibility is currently unknown....
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Sleep patterns, genetic susceptibility, and risk of cirrhosis among individuals with nonalcoholic fatty liver disease
BackgroundThe associations between sleep patterns or behaviors and the risk of cirrhosis and the influence of genetic susceptibility on these...
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Quantitative susceptibility map** demonstrates different patterns of iron overload in subtypes of early-onset Alzheimer’s disease
ObjectivesWe aimed to define brain iron distribution patterns in subtypes of early-onset Alzheimer’s disease (EOAD) by the use of quantitative...
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Genetically transitional disease: conceptual understanding and applicability to rheumatic disease
In genomic medicine, the concept of genetically transitional disease (GTD) refers to cases in which gene mutation is necessary but not sufficient to...
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Sleep duration, genetic susceptibility, and Alzheimer's disease: a longitudinal UK Biobank-based study
BackgroundAlzheimer's disease (AD) is the most frequently occurring type of dementia. Concurrently, inadequate sleep has been recognized as a public...
