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Map** high-grade glioma immune infiltration to 5-ALA fluorescence levels: TCGA data computation, classical histology, and digital image analysis
PurposeResection of high-grade gliomas has been considerably improved by 5-aminolevulinic acid (5-ALA). However, not all neurobiological properties...
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5-ALA fluorescence-guided resection of pediatric low-grade glioma using the ORBEYE 3D digital exoscope: a technical report
ObjectiveA case of low-grade glioma in which 5-aminolevulinic acid (5-ALA) fluorescence was visualized by a digital exoscope is presented.
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Liver fibrosis analysis using digital pathology
Digital pathology has enabled the noninvasive quantification of pathological parameters. In addition, the combination of digital pathology and...
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Defining digital surgery: a SAGES white paper
BackgroundDigital surgery is a new paradigm within the surgical innovation space that is rapidly advancing and encompasses multiple areas.
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Assessing the benefits of digital twins in neurosurgery: a systematic review
Digital twins are virtual replicas of their physical counterparts, and can assist in delivering personalized surgical care. This PRISMA...
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Digital pathology for nonalcoholic steatohepatitis assessment
Histological assessment of nonalcoholic fatty liver disease (NAFLD) has anchored knowledge development about the phenotypes of the condition, their...
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Digital pathology in Latin America
Digital pathology (DP) adoption in Latin America has expanded slower than in developed regions, probably due to many barriers not seen in the latter...
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Optimization of novel exoscopic blue light filter during fluorescence-guided resection of Glioblastoma
PurposeOperative guidelines and use optimization for new surgical exoscopes are not well described in the literature. In this study, we evaluated use...
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Digital in-line holographic microscopy for label-free identification and tracking of biological cells
Digital in-line holographic microscopy (DIHM) is a non-invasive, real-time, label-free technique that captures three-dimensional (3D) positional,...
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Effectiveness of indocyanine green fluorescence imaging in resection of hepatoblastoma
ObjectiveThe present research aimed to analyze the application of indocyanine green (ICG) fluorescence contrast technique in the resection of...
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Rapid digital pathology of H&E-stained fresh human brain specimens as an alternative to frozen biopsy
BackgroundHematoxylin and Eosin (H&E)-based frozen section (FS) pathology is presently the global standard for intraoperative tumor assessment (ITA)....
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Augmented Reality Navigation Plus Indocyanine Green Fluorescence Imaging Can Accurately Guide Laparoscopic Anatomical Segment 8 Resection
BackgroundLaparoscopic anatomical Segment 8 (S8) resection is a highly challenging hepatectomy. Augmented reality navigation (ARN), which could be...
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Fluorescence use in minimally invasive metabolic and bariatric surgery — a systematic review of the literature
PurposeThis review aims to explore and summarise current knowledge of indocyanine green (ICG) fluorescence application in metabolic and bariatric...
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Clinical application of the HM-1000 image processing for HER2 fluorescence in situ hybridization signal quantification in breast cancer
BackgroundAccurate quantification of human epidermal growth factor receptor 2 ( HER2 ) gene amplification is important for predicting treatment...
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Case report: video-assisted thoracoscopic surgery for pulmonary arteriovenous malformation using near-infrared fluorescence with indocyanine green
BackgroundPulmonary arteriovenous malformation (PAVM) is an abnormal communication between pulmonary vasculatures and has an unclear boundary with...
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Development of a droplet digital PCR method for detection of porcine circovirus 4
BackgroundPorcine circovirus 4 (PCV4), a newly emerging virus that was first discovered in 2019, may pose a potential threat to the pig industry....
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Improvements in digital pathology equipment for renal biopsies: updating the standard model
IntroductionDigital pathology can improve the technical and interpretative workflows in nephropathology by creating hub-spoke networks and virtuous...
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Augmented Reality Navigation System and Indocyanine Green Fluorescence Imaging Make Laparoscopic Right Anterior Sectionectomy More Precisely and Safely
BackgroundLaparoscopic right anterior sectionectomy (LRAS) is an attractive surgical option for tumors in the right anterior section (RAS), which can...
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First-in-man study of the PSMA Minibody IR800-IAB2M for molecularly targeted intraoperative fluorescence guidance during radical prostatectomy
PurposeProstate-specific membrane antigen (PSMA) is increasingly used to image prostate cancer in clinical practice. We sought to develop and test a...
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Deconstructing mastery in colorectal fluorescence angiography interpretation
IntroductionIndocyanine green fluorescence angiography (ICGFA) is commonly used in colorectal anastomotic practice with limited pre-training. Recent...
