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Paroxysmal sympathetic hyperactivity following acute diffuse brain swelling due to traumatic brain injury: a case report with good clinical outcome
BackgroundParoxysmal sympathetic hyperactivity (PSH) may occur after acquired brain injury. The clinical presentation of PSH results from increased...
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Pain inhibition—the unintended benefit of electrically elicited muscle strengthening contractions
BackgroundNeuromuscular electrical stimulation (NMES) is effective in muscle strengthening after orthopedic injury particularly when muscle...
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Paroxysmal sympathetic hyperactivity in a child with stroke: a case report
BackgroundParoxysmal sympathetic hyperactivity (PSH) is the result of dysregulated autonomic function with sympathetic symptoms characterised by...
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Paroxysmal Sympathetic Hyperactivity After Acquired Brain Injury: An Integrative Review of Diagnostic and Management Challenges
Paroxysmal sympathetic hyperactivity (PSH) mainly occurs after acquired brain injury (ABI) and often presents with high fever, hypertension,...
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Effects of progressive intensity resistance training on the impact of fibromyalgia: protocol for a blinded randomized controlled trial
BackgroundFibromyalgia guidelines indicate that exercise is critical in the management of fibromyalgia, and there is evidence that patients with...
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Enhanced pain facilitation rather than impaired pain inhibition in burning mouth syndrome female patients
BackgroundDeficient endogenous pain modulation has been implicated in the development and exacerbation of chronic orofacial pain. To date, relatively...
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The development of descending serotonergic modulation of the spinal nociceptive network: a life span perspective
AbstractThe nociceptive network, responsible for transmission of nociceptive signals that generate the pain experience, is not fully developed at...
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The ED50 and ED95 of esketamine for preventing early postoperative pain in patients undergoing laparoscopic cholecystectomy: a prospective, double-blinded trial
BackgroundThis study aims to estimate the safety, efficacy, and median effective dose (ED50) of esketamine for preventing early postoperative pain in...
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Pain mechanisms in complex regional pain syndrome: a systematic review and meta-analysis of quantitative sensory testing outcomes
BackgroundComplex regional pain syndrome (CRPS) is a chronic condition following inciting events such as fractures or surgeries with sensorimotor and...
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Photobiomodulation enhanced endogenous pain modulation in healthy volunteers
To examine the effects of photobiomodulation (PBM) in healthy volunteers using photonic stimulation of acupuncture points on conditioned pain...
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What goes up must come down: insights from studies on descending controls acting on spinal pain processing
Descending controls link higher processing of noxious signals to modulation of spinal cord responses to their noxious inputs. It has become possible...
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Analgesic effects of LI4 acupuncture during intrauterine device insertion: a randomized controlled clinical trial
PurposeIntrauterine device (IUD) is one the most effective contraceptive methods with reversible long-term effects. However, the major drawback of...
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Central neuropathic pain
Central neuropathic pain arises from a lesion or disease of the central somatosensory nervous system such as brain injury, spinal cord injury,...
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Effects of self-myofascial release interventions with or without sliding pressures on skin temperature, range of motion and perceived well-being: a randomized control pilot trial
BackgroundSelf-myofascial release is an emerging technique in strength and conditioning. Yet, there is no consensus regarding optimal practice...
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Collateral projections from the ventral tegmental area/substantia nigra pars compacta to the nucleus accumbens and insular cortex in the rat
Midbrain dopaminergic (DAergic) regions including ventral tegmental area (VTA) and substantia nigra pars compacta (SNc) are involved in diverse brain...
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Four Decades of Occipital Nerve Stimulation for Headache Disorders: A Systematic Review
Purpose of ReviewChronic headaches are a significant source of disability worldwide. Despite the development of conventional strategies, a subset of...
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Type-1 diabetes mellitus down-regulated local cerebral glial fibrillary acidic protein expression in experimental toxoplasmosis
Cerebral toxoplasmosis is an opportunistic infection, occurring mostly in immunosuppressed patients due to the reactivation of latent Toxoplasma ...
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Clinical criteria and diagnostic assessment of fibromyalgia: position statement of the Italian Society of Neurology-Neuropathic Pain Study Group
BackgroundThe role of central and/or peripheral nervous system dysfunction is basically fundamental in fibromyalgia.
AimThe aim of this position...
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Bilateral Sensorimotor Impairments in Individuals with Unilateral Chronic Ankle Instability: A Systematic Review and Meta-Analysis
BackgroundChronic ankle instability (CAI) is manifested by sensorimotor impairments in the sprained ankle, including deficits in sensation, motor...
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Electronic Health Record Recording of Patient Pain: Challenges and Discrepancies
Purpose of ReviewIn the present review, various categories of pain, clinician-observed pain scales, and patient-reported pain scales are evaluated to...