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Enigma of Intramuscular Triamcinolone Acetonide (Kenalog®) Efficacy
Triamcinolone acetonide is a glucocorticosteroid used in standard clinical practice for its anti-inflammatory properties. Although it can be given...
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Stratum corneum substantivity: drug development implications
There are at least 15 factors that influence the ability of chemicals to penetrate the skin. Substantivity is yet another factor and allows...
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Stress and Skin Disorders Basic and Clinical Aspects
Dermatological conditions are intimately related to stress. Stress can affect, reveal or even exacerbate a number of skin disorders, including...
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Retinoid treatment of skin diseases
Retinoids (vitamin A and its metabolites) are potent natural regulators of cellular activities, including cell growth and differentiation, and they...
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Retinoide in der Dermatopharmakologie
BackgroundRetinoids are important in regulating cell proliferation and differentiation and play an important role in the body, including the skin.
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Sirtuins in dermatology: applications for future research and therapeutics
Sirtuins are a family of seven proteins in humans (SIRT1–SIRT7) that are involved in multiple cellular processes relevant to dermatology. The role of...
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Susceptibility testing of dermatophytes
The dermatophytes are a specialized group of fungi that infect the keratinized tissues of humans (hair, nails, and skin) and cause superficial...
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Lack of Drug Interaction Conformity in Commonly Used Drug Compendia for Selected At-Risk Dermatologic Drugs
Background : Systemic treatments that have significant efficacy for dermatologic conditions can often cause severe adverse reactions when improperly...
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Nichtinvasive Diagnostik von Hautfunktionen
Noninvasive investigation of skin functions is increasingly employed in dermatology and cosmetology. It enables one to study aspects of skin...
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Racial (Ethnic) Differences in Skin Properties
Racial (ethnic) differences in skin properties may explain racial disparities seen in dermatologic disorders and provide insight into appropriate...
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Dermatologische Perspektiven im 21. Jahrhundert
During the last decades dermatology has been profoundly transformed from its descriptive origin into an important part of modern medicine and...
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Radiogene Akne
Radiation-induced acne is a rare, clinically and pathogenetically ill-defined acneiform dermatosis with special features that may occur in irradiated...
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Second-Generation Antihistamines
Second-generation histamine H 1 receptor antagonists (antihistamines) have been developed to reduce or eliminate the sedation and anticholinergic...
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Evaluation of RU58841 as an anti-androgen in prostate PC3 cells and a topical anti-alopecia agent in the bald scalp of stumptailed macaques
The effect of androgen receptor transcriptional activation by RU58841, a nonsteroidal anti-androgen, was studied in the human prostate cancer PC3...
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Dermatological Uses of Cyclosporin
Numerous dermatoses have been successfully treated with cyclosporin. This review summarises much of the literature describing cyclosporin therapy for...