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Assessment of peripheral dose as a function of distance and depth from cobalt-60 beam in water phantom using TLD-100
BackgroundInnovations in cancer treatment have contributed to the improved survival rate of cancer patients. The cancer survival rates have been...
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A Hybrid Framework of Dual-Domain Signal Restoration and Multi-depth Feature Reinforcement for Low-Dose Lung CT Denoising
Low-dose computer tomography (LDCT) has been widely used in medical diagnosis. Various denoising methods have been presented to remove noise in LDCT...
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Surface dose and build-up region depth dose measurements in non-standard beams of Cyberknife and tomotherapy systems
The purpose of this study was to measure the surface dose and build-up region depth dose characteristics of 6 MV photon beams in Cyberknife and...
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Monte carlo simulation study on the dose and dose-averaged linear energy transfer distributions in carbon ion radiotherapy
Dose-averaged linear energy transfer (LET d ) is conventionally evaluated from the relative biological effectiveness (RBE)-LET d fitted function used in...
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A systematic review and meta-analysis of randomized controlled trials comparing low-dose versus standard-dose computed tomography-guided lung biopsy
BackgroundDespite the existence of several Randomized Controlled Trials (RCTs) investigating Low-Dose Computed Tomography (LDCT) as a guide in lung...
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Reconsidering pregnancy screening policies for minors: patient-specific estimate of fetus and effective dose for potentially pregnant minors undergoing optimized dose CT of the pelvis
BackgroundOnly verbal pregnancy screening is recommended for post-menarcheal females undergoing pelvic radiographs. In contrast, usually, a...
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Effective bolus dose of remimazolam for i-gel® insertion in nonparalyzed patients: a dose-finding study
PurposeRemimazolam is a recently developed ultra-short-acting benzodiazepine used for anesthesia induction and maintenance. Nevertheless, the...
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Using part of the initial analgesic dose as the epidural test dose did not delay the onset of labor analgesia: a randomized controlled clinical trial
BackgroundEpidural test dose for labor analgesia is controversial and varies widely in clinical practice. It is currently unclear whether using a...
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Feasibility of the pupillary pain index as a guide for depth of analgesia during opioid-sparing anesthesia with continuous infusion of dexmedetomidine
BackgroundThe pupillary dilation reflex (PDR) is an objective indicator of analgesic levels in anesthetized patients. Through measurement of the PDR...
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The Effect of Depth of Anesthesia on Postoperative Pain in Laparoscopic Sleeve Gastrectomy: A Randomized Controlled Trial
BackgroundPatients with obesity are more sensitive to pain and more likely to have acute postoperative pain (APP). Studies have shown that the depth...
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Dose-related adaptive reconstruction of DMN in isoflurane administration: a study in the rat
BackgroundThe anesthetic states are accompanied by functional alterations. However, the dose-related adaptive alterations in the higher-order network...
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Monitoring Depth of Neuromuscular Blockade and Adequacy of Reversal: Clinical and Pharmacoeconomic Implications
Purpose of ReviewThis review summarizes current evidence on best practice management of neuromuscular blocking agents (NMBAs). Furthermore, the...
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Health system barriers to the first dose of measles immunization in Ethiopia: a qualitative study
BackgroundEthiopia has made considerable progress toward measles elimination. Despite ongoing efforts, the country remains among those with the...
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Patient and public involvement and engagement in the development of innovative patient-centric early phase dose-finding trial designs
BackgroundIn light of the FDA’s Project Optimus initiative, there is fresh interest in leveraging Patient-reported Outcome (PRO) data to enhance the...
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Ultra-high resolution computed tomography with deep-learning-reconstruction: diagnostic ability in the assessment of gastric cancer and the depth of invasion
PurposeTo evaluate the image quality of ultra-high-resolution CT (U-HRCT) images reconstructed using an improved deep-learning-reconstruction (DLR)...
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Impact of dose volume parameters and clinical characteristics on radiation-induced acute oral mucositis for head and neck cancer patients treated with carbon-ion radiotherapy dose volume outcome analysis
ObjectivesTo assess the predictive value of different dosimetric parameters for acute radiation oral mucositis (ROM) in head and neck cancer (HNCs)...
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Monitoring Depth of Neuromuscular Blockade
Purpose of ReviewThis review discusses alternative quantitative neuromuscular blockade monitoring methods and advantages and disadvantages of each...
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Predictors of pediatric sedation failure with initial dose of intranasal dexmedetomidine and oral midazolam
BackgroundTo assess the sedative failure rate over different dose combinations of intranasal dexmedetomidine and oral midazolam for procedural...
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The effect of anesthetic depth on postoperative delirium in older adults: a systematic review and meta-analysis
BackgroundPostoperative delirium (POD) is an important complication for older patients and recent randomised controlled trials have showed a...