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Cholinergic Boutons are Distributed Along the Dendrites and Somata of VIP Neurons in the Inferior Colliculus
Cholinergic signaling shapes sound processing and plasticity in the inferior colliculus (IC), the midbrain hub of the central auditory system, but...
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Granulocyte macrophage colony-stimulating factor-induced macrophages of individuals with autism spectrum disorder adversely affect neuronal dendrites through the secretion of pro-inflammatory cytokines
BackgroundA growing body of evidence suggests that immune dysfunction and inflammation in the peripheral tissues as well as the central nervous...
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Dendritiform immune cells with reduced antigen-capture capacity persist in the cornea during the asymptomatic phase of allergic conjunctivitis
BackgroundIncreased density and altered morphology of dendritic cells (DC) in the cornea and conjunctiva occur during active allergic conjunctivitis....
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Absence of parvalbumin increases mitochondria volume and branching of dendrites in inhibitory Pvalb neurons in vivo: a point of convergence of autism spectrum disorder (ASD) risk gene phenotypes
BackgroundIn fast firing, parvalbumin (PV)-expressing (Pvalb) interneurons, PV acts as an intracellular Ca 2+ signal modulator with slow-onset...
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Increased dendritic cell density and altered morphology in allergic conjunctivitis
BackgroundCorneal and conjunctival epithelial dendritic cells (DC) have an established role in vernal keratoconjunctivitis, however, their role in...
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Synaptic configuration and reconfiguration in the neocortex are spatiotemporally selective
Brain computation relies on the neural networks. Neurons extend the neurites such as dendrites and axons, and the contacts of these neurites that...
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Correction to: Absence of parvalbumin increases mitochondria volume and branching of dendrites in inhibitory Pvalb neurons in vivo: a point of convergence of autism spectrum disorder (ASD) risk gene phenotypes
An amendment to this paper has been published and can be accessed via the original article.
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Neurotrophin-3 from the dentate gyrus supports postsynaptic sites of mossy fiber-CA3 synapses and hippocampus-dependent cognitive functions
At the center of the hippocampal tri-synaptic loop are synapses formed between mossy fiber (MF) terminals from granule cells in the dentate gyrus...
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Pathways Controlling Formation and Maintenance of the Osteocyte Dendrite Network
Purpose of ReviewThe purpose of this review is to discuss the molecular mechanisms involved in osteocyte dendrite formation, summarize the...
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Early and selective localization of tau filaments to glutamatergic subcellular domains within the human anterodorsal thalamus
Widespread cortical accumulation of misfolded pathological tau proteins (ptau) in the form of paired helical filaments is a major hallmark of...
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Fyn nanoclustering requires switching to an open conformation and is enhanced by FTLD-Tau biomolecular condensates
Fyn is a Src kinase that controls critical signalling cascades and has been implicated in learning and memory. Postsynaptic enrichment of Fyn...
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Cranial irradiation induces cognitive decline associated with altered dendritic spine morphology in the young rat hippocampus
ObjectiveTherapeutic irradiation is commonly used to treat brain cancers but can induce cognitive dysfunction, especially in children. The mechanism...
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Expression analyses of WAC, a responsible gene for neurodevelopmental disorders, during mouse brain development
WAC is an adaptor protein involved in gene transcription, protein ubiquitination, and autophagy. Accumulating evidence indicates that WAC gene...
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Inverse pattern of GABAergic system impairment in the external versus internal globus pallidus in male heroin addicts
Opioid addiction is a global problem that has been exacerbated in the USA and Europe by the COVID-19 pandemic. The globus pallidus (GP) plays a...
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Celsr2 regulates NMDA receptors and dendritic homeostasis in dorsal CA1 to enable social memory
Social recognition and memory are critical for survival. The hippocampus serves as a central neural substrate underlying the dynamic coding and...
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Enhanced hippocampal LTP but normal NMDA receptor and AMPA receptor function in a rat model of CDKL5 deficiency disorder
BackgroundMutations in the X-linked gene cyclin-dependent kinase-like 5 ( CDKL5 ) cause a severe neurological disorder characterised by early-onset...
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A whole transcriptome profiling analysis for antidepressant mechanism of **aoyaosan mediated synapse loss via BDNF/trkB/PI3K signal axis in CUMS rats
BackgroundDepression is a neuropsychiatric disease resulting from deteriorations of molecular networks and synaptic injury induced by stress....
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DPYSL2/CRMP2 isoform B knockout in human iPSC-derived glutamatergic neurons confirms its role in mTOR signaling and neurodevelopmental disorders
The DPYSL2/CRMP2 gene encodes a microtubule-stabilizing protein crucial for neurogenesis and is associated with numerous psychiatric and...
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Aberrant hippocampal transmission and behavior in mice with a stargazin mutation linked to intellectual disability
Mutations linked to neurodevelopmental disorders, such as intellectual disability (ID), are frequently found in genes that encode for proteins of the...
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A de novo missense mutation in synaptotagmin-1 associated with neurodevelopmental disorder desynchronizes neurotransmitter release
Synaptotagmin-1 (Syt1) is a presynaptic calcium sensor with two calcium binding domains, C2A and C2B, that triggers action potential-induced...
