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Heightened Prevalence of Common Hospital-Treated Infections Preceding Dementia Diagnosis with Accelerated Dementia Onset after Influenza
BackgroundSince the beginning of Alzheimer’s disease research, the hypothesis that infections are to some extent associated with neurodegenerative...
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Post-diagnostic support for persons with young-onset dementia – a retrospective analysis based on data from the Swedish dementia registry SveDem
BackgroundApproximately 3.9 million persons worldwide have young-onset dementia. Symptoms related to young-onset dementia present distinct challenges...
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Electroencephalography in young onset dementia
BackgroundYoung onset dementia (YOD) is a major diagnostic and management problem.
MethodsWe set out to explore if electroencephalography (EEG)...
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Young-onset Alzheimer’s dementia mimicking progressive myoclonic epilepsy spectrum
BackgroundYoung-onset Alzheimer’s dementia (YOAD) refers to the onset of disease before the age of 40 years. Classical AD typically presents with...
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How long does it take to diagnose young-onset dementia? A comparison with late-onset dementia
IntroductionDementia occurring in young people may be difficult to recognize. We compared the time to diagnosis between young- (YOD, age < 65) and...
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Cognitive trajectories preluding the onset of different dementia entities: a descriptive longitudinal study using the NACC database
ObjectiveTo describe the 10-year preclinical cognitive trajectories of older, non-demented individuals towards the onset of the four most prevalent...
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Cognitive impairment and dementia in young onset Parkinson’s disease
Background and objectivePatients with young-onset Parkinson’s disease (YOPD) have a slower progression. Our aim was to analyze the change in...
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The clinical phenotype of psychiatric-onset prodromal dementia with Lewy bodies: a sco** review
BackgroundRecent consensus research criteria have identified a ‘psychiatric onset’ form of prodromal dementia with Lewy bodies (DLB) characterised by...
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Age-specific prevalence of the different clinical presentations of AD and FTD in young-onset dementia
BackgroundStudies have shown that the prevalence of all-variants Alzheimer’s disease (AD) and frontotemporal dementia (FTD) both increase with age,...
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Map** the complexity of dementia: factors influencing cognitive function at the onset of dementia
BackgroundDementia is a multi-factorial condition rather than a natural and inevitable consequence of ageing. Some factors related to dementia have...
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Early onset frontotemporal dementia following cannabis abuse: a case report
BackgroundFrontotemporal disorders (FTD) are the consequence of impairment to neurons in the frontal and temporal lobes of the brain. Also, no...
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Genetic landscape of early-onset dementia in Hungary
IntroductionEarly-onset dementias (EOD) are predominantly genetically determined, but the underlying disease-causing alterations are often unknown....
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Baseline Findings of PreventE4: A Double-Blind Placebo Controlled Clinical Trial Testing High Dose DHA in APOE4 Carriers before the Onset of Dementia
IntroductionLower blood levels of the omega-3 polyunsaturated fatty acid docosahexaenoic acid (DHA) are correlated with worse cognitive functions,...
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Alcohol use, dementia risk, and sex: a systematic review and assessment of alcohol-attributable dementia cases in Europe
BackgroundHigh-risk alcohol use is an established modifiable risk factor for dementia. However, prior reviews have not addressed sex differences in...
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Rural-urban disparities in preventive breast and cervical cancer screening among women with early-onset dementia
BackgroundThe early onset of Alzheimer’s disease and related dementias (ADRD) before age 65 can introduce life and health care complications....
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Late-onset epilepsy and the risk of dementia: a systematic review and meta-analysis
BackgroundPatients with dementia have higher risk of epilepsy. However, it remains not comprehensively evaluated if late-onset epilepsy (LOE) is...
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Brain structural abnormalities and cognitive changes in a patient with 17q21.31 microduplication and early onset dementia: a case report
ObjectivesWe describe brain structural damage and cognitive profile evolution of an adult patient with 17q21.31 microduplication, a rare condition...
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Brain Sagging Dementia
Purpose of ReviewBrain sagging dementia (BSD) is a rare but devastating form of early-onset dementia characterized by intracranial hypotension and...
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