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Using part of the initial analgesic dose as the epidural test dose did not delay the onset of labor analgesia: a randomized controlled clinical trial
BackgroundEpidural test dose for labor analgesia is controversial and varies widely in clinical practice. It is currently unclear whether using a...
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Follow-up outcome analysis of 324 cases of early-onset and late-onset mild fetal ventriculomegaly: a retrospective cohort study
BackgroundMild fetal ventriculomegaly (VM) is a nonspecific finding common to several pathologies with varying prognosis and is, therefore, a...
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Early-onset alcohol, tobacco, and illicit drug use with age at onset of hypertension: a survival analysis
PurposeTo examine the associations of age when first substance use and early-onset substance use before age 18 with age at onset (AAO) of...
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Treatment Gap of Mental Disorders in São Paulo Metropolitan Area, Brazil: Failure and Delay in Initiating Treatment Contact After First Onset of Mental and Substance Use Disorders
An under-studied crucial step in the health-related help-seeking process is making prompt contact with a treatment provider when a mental disorder...
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Diagnostic delay of sarcoidosis: an integrated systematic review
BackgroundSarcoidosis is a chronic inflammatory granulomatous disease of unknown cause. Delays in diagnosis can result in disease progression and...
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Diagnostic delay in patients with giant cell arteritis: results of a fast-track clinic
Giant cell arteritis (GCA) can lead to severe complications if left untreated. The aim of this study was to describe time from onset of symptoms to...
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Diagnostic delay in psoriatic arthritis: insights from a nationwide multicenter study
This study aimed to investigate the duration of diagnostic delay in patients with psoriatic arthritis (PsA) and identify potential contributing...
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Clinical and laboratory characteristics of early-onset and delayed-onset lupus nephritis patients: A single-center retrospective study
BackgroundLupus nephritis (LN) manifests systemic lupus erythematosus (SLE) and is characterized by various clinical and laboratory features. This...
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Prevalence, risk factors and multiple outcomes of treatment delay in Chinese patients with schizophrenia
BackgroundPeople with schizophrenia often delay treatment. This issue is not fully understood, particularly in low-and middle-income countries. This...
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Effect of in-hospital delay on acute appendicitis severity: does time really matter?
Appendicitis is one of the most common abdominal emergencies. Evidence is controversial in determining if the in-hospital time delay to surgery can...
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Prevalence and influencing factors of patient delay in stroke patients: a systematic review and meta-analysis
Purpose: Determine the prevalence and influencing factors of patient delay in stroke patients and explore variation in prevalence by country and...
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Diagnostic delay of myositis: an integrated systematic review
BackgroundIdiopathic inflammatory myopathies (IIM) are a heterogenous group of rare muscular autoimmune diseases characterised by skeletal muscle...
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Slower clozapine titration is associated with delayed onset of clozapine-induced fever among Japanese patients with schizophrenia
Clozapine-induced fever marks the beginning of its inflammatory and potentially life-threatening adverse effects, such as myocarditis. We...
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Shared and unique alterations of large-scale network connectivity in drug-free adolescent-onset and adult-onset major depressive disorder
Differences in clinical manifestations and biological underpinnings between Major Depressive Disorder (MDD) onset during adolescence and adulthood...
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Adolescence-onset atypical hemolytic uremic syndrome: is it different from infant-onset?
BackgroundAtypical hemolytic uremic syndrome (aHUS) is a rare, mostly complement-mediated thrombotic microangiopathy. The majority of patients are...
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Delay in the diagnosis of paediatric brain tumours: a systematic review
PurposeA delay in obtaining a diagnosis has been associated with inferior outcomes across several cancer types, including paediatric brain tumours....
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Factors associated with prehospital delay in acute myocardial infarction in Maldives
BackgroundAcute myocardial infarction (AMI) is the top cause of death in Maldives. Our study aims to determine the prehospital delay and its...
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Diagnostic delay in adult inflammatory bowel disease: A systematic review
BackgroundThe extent of diagnostic delay in inflammatory bowel disease (IBD) is incompletely understood. We aimed to understand the extent of...
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Effect of diagnosis delay on pulmonary function in children with asthma
BackgroundThe effects of a delayed diagnosis of asthma on lung function in children have not been well investigated. Therefore, a retrospective...