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  1. Degenerative mitral regurgitation

    Degenerative mitral regurgitation is a major threat to public health and affects at least 24 million people worldwide, with an estimated 0.88 million...

    Victoria Delgado, Nina Ajmone Marsan, ... Michael A. Borger in Nature Reviews Disease Primers
    Article 07 December 2023
  2. Insights into the underlying pathogenesis and therapeutic potential of endoplasmic reticulum stress in degenerative musculoskeletal diseases

    Degenerative musculoskeletal diseases are structural and functional failures of the musculoskeletal system, including osteoarthritis, osteoporosis,...

    Ze-Qin Wen, Jun Lin, ... Yu-Sheng Li in Military Medical Research
    Article Open access 09 November 2023
  3. Degenerative tendon matrix induces tenogenic differentiation of mesenchymal stem cells

    Purpose

    Mesenchymal stem cells (MSCs) react dynamically with the surrounding microenvironment to promote tissue-specific differentiation and hence...

    Joongwon Hwang, Seung Yeon Lee, Chris Hyunchul Jo in Journal of Experimental Orthopaedics
    Article Open access 14 February 2023
  4. Phenomenology of spontaneous closure in degenerative and mixed type lamellar macular hole

    Purpose

    To the describe OCT imaging characteristics of a cohort of patients showing spontaneously closing degenerative or mixed type lamellar macular...

    Fiammetta Catania, Mario R. Romano, ... Georges Caputo in Eye
    Article 31 July 2023
  5. Prevalence of degenerative vertebral disc changes in elite female Crossfit athletes – a cross-sectional study

    Background

    Crossfit athletes consistently recruit or transfer high levels of repetitive forces through the spine, and MRI has documented a higher rate...

    Mathis Wegner, Jan-Christoph Backhauß, ... Sebastian Lippross in BMC Musculoskeletal Disorders
    Article Open access 11 December 2023
  6. The role of the greater trochanter pain syndrome in lumbar degenerative disc disease surgery

    Purpose

    Greater trochanter pain syndrome (GTPS) is highly discussed during spine surgeons, accompanies lumbar pain and complicates differential...

    Arkadii I. Kazmin, Vladimir S. Pereverzev, ... Sergey V. Kolesov in International Orthopaedics
    Article 14 May 2024
  7. Deep learning-based high-accuracy detection for lumbar and cervical degenerative disease on T2-weighted MR images

    Purpose

    To develop and validate a deep learning (DL) model for detecting lumbar degenerative disease in both sagittal and axial views of T2-weighted...

    Wei Yi, **gwei Zhao, ... Wei Tian in European Spine Journal
    Article Open access 21 March 2023
  8. Intra-cerebellar schwannoma with various degenerative changes: a case report and a systematic review

    Background

    Intra-cranial schwannomas account for less than 8% of brain tumors, among which more than 80% arise from the vestibular nerve....

    Yasuhide Takeuchi, Yoshiki Arakawa, ... Hironori Haga in BMC Neurology
    Article Open access 24 February 2022
  9. Mitral degenerative valve leaflets suspected as primary valvular tumor: a case report

    Background

    Echocardiography plays an important role in the diagnosis of heart disease. Sometimes, however, it may also provide misdiagnosis...

    Shiqiang Wang, Huaidong Chen, ... Fan He in BMC Cardiovascular Disorders
    Article Open access 22 February 2023
  10. Photon-counting CT of degenerative changes and rupture of silicone breast implants: a pilot study

    Background

    Accurate assessment of breast implants is important for appropriate clinical management. We evaluated silicone properties and diagnostic...

    Claudia Neubauer, Oliver Gebler, ... Jakob Neubauer in European Radiology Experimental
    Article Open access 14 March 2024
  11. Are degenerative findings detected on traction MR arthrography of the hip associated with failure of arthroscopic femoroacetabular im**ement surgery?

    Objectives

    To identify preoperative degenerative features on traction MR arthrography associated with failure after arthroscopic femoroacetabular...

    Till D. Lerch, Andreas K. Nanavati, ... Florian Schmaranzer in European Radiology
    Article Open access 20 November 2023
  12. Degenerative medial and lateral menisci root tears: demographics, clinical presentation, imaging features, and associated findings

    Purpose

    (I) Characterize the demographics and clinical features of patients with meniscal root tears (MRT); (II) analyze the morphology, extent, and...

    Julio B. Guimaraes, Rawee Manatrakul, ... Thomas M. Link in Skeletal Radiology
    Article 25 June 2024
  13. The efficacy of 3D gait analysis to evaluate surgical (and rehabilitation) outcome after degenerative lumbar surgery

    Background

    Lumbar degenerative conditions are a major cause of back pain and disability in individuals aged 45 and above. Gait analysis utilizes...

    Chao Zhou, Ning Zhou, ... Jun Yin in BMC Surgery
    Article Open access 26 June 2024
  14. A novel mini-open transforaminal lumbar interbody fusion for lumbar degenerative diseases: technical note and preliminary results

    Background

    Transforaminal lumbar interbody fusion (TLIF) is an effective and popular surgical procedure for the management of various spinal...

    Yuhang Ma, Kelv Shen, ... Zhengfeng Lu in Journal of Orthopaedic Surgery and Research
    Article Open access 20 July 2023
  15. SLAP lesion type IX: case series and a review of literature

    Purpose

    A type IX SLAP (superior labrum anterior to posterior) lesion involves 360° of the glenohumeral labrum. Only rare reports have been published...

    Benjamin Marjanovič, Tina Ušaj, ... Marko Nabergoj in European Journal of Orthopaedic Surgery & Traumatology
    Article 19 April 2023
  16. Intra-articular injections in sport-active patients with degenerative cartilage lesions or osteoarthritis of the knee: a systematic review

    Purpose

    The aim of this systematic review was to analyse the available clinical evidence on intra-articular knee injections for the treatment of...

    Luca De Marziani, Alessandro Sangiorgio, ... Giuseppe Filardo in Journal of Experimental Orthopaedics
    Article Open access 08 November 2023
  17. MRI-based vertebral bone quality score for the assessment of osteoporosis in patients undergoing surgery for lumbar degenerative diseases

    Purpose

    To explore the value of vertebral bone quality (VBQ) scores in diagnosing osteoporosis in patients with lumbar degeneration.

    Methods ...
    Zan Chen, Fei Lei, ... Daxiong Feng in Journal of Orthopaedic Surgery and Research
    Article Open access 29 March 2023
  18. Intra-articular administration of extra-virgin olive oil in degenerative osteoarthritis

    Background

    We aimed to analyze the outcomes of intraarticular extra virgin olive oil (EVOO) injection on mechanically induced rabbit knee...

    Ahmet Pamiry, Mehmet Yiğit Gökmen, Mustafa Tekin in Journal of Orthopaedic Surgery and Research
    Article Open access 08 June 2024
  19. Spontaneous closure of degenerative lamellar macular hole with epiretinal membrane proliferation

    Background

    To describe the spontaneous closure of a degenerative lamellar macular hole with epiretinal proliferation (LHEP) as documented with tracked...

    Rony C. Preti, Leandro C. Zacharias, ... David Sarraf in International Journal of Retina and Vitreous
    Article Open access 26 October 2021
  20. Minimally invasive lateral single-position surgery for multilevel degenerative lumbar spine disease: feasibility and perioperative results in a single Latin-American spine center

    Introduction

    Within advances in minimally invasive spine surgery, the implementation of lateral single position (LSP) increases efficiency while...

    Sara Henao Romero, Miguel Berbeo, ... Daniel Villamizar Torres in European Spine Journal
    Article 24 March 2023
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