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Days alive and out of hospital for adult female and male cardiac surgery patients: a population-based cohort study
BackgroundResearch shows women experience higher mortality than men after cardiac surgery but information on sex-differences during postoperative...
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Postoperative high-sensitivity troponin T predicts 1-year mortality and days alive and out of hospital after orthotopic heart transplantation
BackgroundOrthotopic heart transplantation (HTX) is the gold standard to treat end-stage heart failure. Numerous risk stratification tools have been...
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Days at home alive after major surgery in patients with and without diabetes: an observational cohort study
ObjectiveWe hypothesized that days at home alive up to 30 days after surgery (DAH30), a novel patient-centered outcome metric, as well as long-term...
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Use of days alive without life support and similar count outcomes in randomised clinical trials – an overview and comparison of methodological choices and analysis methods
BackgroundDays alive without life support (DAWOLS) and similar outcomes that seek to summarise mortality and non-mortality experiences are...
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Favourable neurological outcome following paediatric out-of-hospital cardiac arrest: a retrospective observational study
BackgroundOut-of-hospital cardiac arrest (OHCA) in children is rare and can potentially result in severe neurological impairment. Our study aimed to...
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Factors associated with circulatory death after out-of-hospital cardiac arrest: a population-based cluster analysis
BackgroundOut-of-hospital cardiac arrest (OHCA) is a common cause of death. Early circulatory failure is the most common reason for death within the...
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Cumulative dose of epinephrine and mode of death after non-shockable out-of-hospital cardiac arrest: a registry-based study
BackgroundEpinephrine increases the chances of return of spontaneous circulation (ROSC) in out-of-hospital cardiac arrest (OHCA), especially when the...
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Prehospital high-dose methylprednisolone in resuscitated out-of-hospital cardiac arrest patients (STEROHCA): a randomized clinical trial
PurposePatients who are successfully resuscitated following out-of-hospital cardiac arrest (OHCA) are still at a high risk of neurological damage and...
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Effect of intra-arrest transport, extracorporeal cardiopulmonary resuscitation and immediate invasive assessment in refractory out-of-hospital cardiac arrest: a long-term follow-up of the Prague OHCA trial
BackgroundRandomized data evaluating the impact of the extracorporeal cardiopulmonary resuscitation (ECPR) approach on long-term clinical outcomes in...
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Patients risk for mortality at 90 days after proximal femur fracture – a retrospective study in a tertiary care hospital
BackgroundDespite improving the management of proximal femur fractures (PFF) with legal requirements of timing the surgery within 24 h, mortality...
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Ventilatory settings in the initial 72 h and their association with outcome in out-of-hospital cardiac arrest patients: a preplanned secondary analysis of the targeted hypothermia versus targeted normothermia after out-of-hospital cardiac arrest (TTM2) trial
PurposeThe optimal ventilatory settings in patients after cardiac arrest and their association with outcome remain unclear. The aim of this study was...
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Comparison of smokers’ mortality with non-smokers following out-of-hospital cardiac arrests: a systematic review and meta-analysis
ObjectiveAlthough some studies have linked smoking to mortality after out-of-hospital cardiac arrests (OHCAs), data regarding smoking and mortality...
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Mortality, morbidity & clinical outcome with different types of vasopressors in out of hospital cardiac arrest patients- a systematic review and meta-analysis
Background & objectiveDespite their continued use, the effectiveness and safety of vasopressors in post-cardiac arrest patients remain controversial....
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Risk factors for bleeding complications in patients undergoing extracorporeal cardiopulmonary resuscitation following out-of-hospital cardiac arrest: a secondary analysis of the SAVE-J II study
BackgroundBleeding is the most common complication in out-of-hospital cardiac arrest (OHCA) patients receiving extracorporeal cardiopulmonary...
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Extracorporeal cardiopulmonary resuscitation for refractory out-of-hospital cardiac arrest: a systematic review and meta-analysis of randomized clinical trials
IntroductionExtracorporeal cardiopulmonary resuscitation (ECPR) is currently recommended as a rescue therapy for selected patients in refractory...
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Prospective comparison of prognostic scores for prediction of outcome after out-of-hospital cardiac arrest: results of the AfterROSC1 multicentric study
BackgroundOut-of-hospital cardiac arrest (OHCA) is a heterogeneous entity with multiple origins and prognoses. An early, reliable assessment of the...
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Impact of the route of adrenaline administration in patients suffering from out-of-hospital cardiac arrest on 30-day survival with good neurological outcome (ETIVIO study)
BackgroundOver the past decades, international guidelines for cardiopulmonary resuscitation (CPR) have changed the recommendation for alternative...
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The impact of lesion complexity on predicting mortality of coronary artery disease patients after out-of-hospital cardiac arrest
IntroductionCoronary artery disease (CAD) is the most frequent cause of out-of-hospital cardiac arrest (OHCA). Nevertheless, there have been limited...