Search
Search Results
-
Analysis of the differential expression and prognostic relationship of DEGs in AML based on TCGA database
BackgroundAcute myeloid leukemia (AML) is a common and lethal hematological malignant hyperplastic disease originating from hematopoietic stem cells....
-
HEMGN and SLC2A1 might be potential diagnostic biomarkers of steroid-induced osteonecrosis of femoral head: study based on WGCNA and DEGs screening
BackgroundSteroid-induced osteonecrosis of the femoral head (SONFH) is a chronic and crippling bone disease. This study aims to reveal novel...
-
The Excess Costs of Depression and the Influence of Sociodemographic and Socioeconomic Factors: Results from the German Health Interview and Examination Survey for Adults (DEGS)
IntroductionThe aim of this study was to estimate excess costs of depression in Germany and to examine the influence of sociodemographic and...
-
Autophagy-related gene model as a novel risk factor for schizophrenia
Autophagy, a cellular process where cells degrade and recycle their own components, has garnered attention for its potential role in psychiatric...
-
Identification of key genes and immune infiltration in osteoarthritis through analysis of zinc metabolism-related genes
BackgroundOsteoarthritis (OA) represents a prominent etiology of considerable pain and disability, and conventional imaging methods lack sensitivity...
-
Transcriptome sequencing and bioinformatics analysis of gastrocnemius muscle in type 2 diabetes mellitus rats
ObjectiveType 2 diabetes mellitus (T2DM) is one of the high risk factors for sarcopenia. However, the pathogenesis of diabetic sarcopenia has not...
-
Identification of shared gene signatures in major depressive disorder and triple-negative breast cancer
BackgroundPatients with major depressive disorder (MDD) have an increased risk of breast cancer (BC), implying that these two diseases share similar...
-
Identification of key differentially expressed immune related genes in patients with persistent atrial fibrillation: an integrated bioinformation analysis
ObjectiveWe aimed to investigate key differentially expressed immune related genes in persistent atrial fibrillation.
MethodsGene expression...
-
Inflammation and immunological disarrays are associated with acute exercise in type 2 diabetes
ObjectiveType 2 diabetes (T2D) is the most common metabolic disorder that is associated with insulin resistance. The aim of the present study is to...
-
Transcriptional landscape of intestinal environment in DSS-induced ulcerative colitis mouse model
Ulcerative colitis (UC) is a chronic inflammatory disease that targets the colon and has seen an increasing prevalence worldwide. In our pursuit of...
-
Bioinformatics-based screening and analysis of the key genes involved in the influence of antiangiogenesis on myeloid-derived suppressor cells and their effects on the immune microenvironment
This study aimed to screen differentially expressed genes (DEGs) involved in the influence of antiangiogenic therapy on myeloid-derived suppressor...
-
Unique transcriptional signatures correlate with behavioral and psychological symptom domains in Alzheimer’s disease
Despite the significant burden, cost, and worse prognosis of Alzheimer’s disease (AD) with behavioral and psychological symptoms of dementia (BPSD),...
-
NF-kappa B signaling pathway is associated with metformin resistance in type 2 diabetes patients
IntroductionMetformin is an essential medicine that is most widely prescribed frontline for the treatment of Type 2 diabetes (T2D). Metformin...
-
The Gene Expression Profiles Associated with Maternal Nicotine Exposure in the Liver of Offspring Mice
This study aims to investigate the effect of maternal nicotine exposure on the gene expression profiles in the liver of offspring mice. Pregnant mice...
-
ceRNA Network and WGCNA Analyses of Differentially Expressed Genes in Cervical Cancer Tissues for Association with Survival of Patients
The study aims to search and identify differentially expressed genes (DEGs) in cervical cancer tissues as novel biomarkers to predict cervical cancer...
-
The identification of hub genes associated with pure ground glass nodules using weighted gene co-expression network analysis
BackgroundWhether there are invasive components in pure ground glass nodules(pGGNs) in the lungs is still a huge challenge to forecast. The objective...
-
Identification of genes and pathways associated with menopausal status in breast cancer patients using two algorithms
BackgroundMenopausal status has a known relationship with the levels of estrogen, progesterone, and other sex hormones, potentially influencing the...
-
Identification of allograft inflammatory factor-1 suppressing the progression and indicating good prognosis of osteosarcoma
BackgroundOsteosarcoma is one of the most common cancers worldwide. Intense efforts have been made to elucidate the pathogeny, but the mechanisms of...
-
Identification of immune-related signature with prognosis in children with stage 4 and 4S neuroblastoma
ObjectiveSpontaneous regression of tumors is an attractive phenomenon that most commonly occurs in stage 4S neuroblastoma (NB). However, the...
-
Exploring the biomarkers and potential therapeutic drugs for sepsis via integrated bioinformatic analysis
BackgroundSepsis is a life-threatening condition caused by an excessive inflammatory response to an infection, associated with high mortality....
