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Fully automated radiosynthesis of [68Ga]Ga-FAPI-46 with cyclotron produced gallium
BackgroundRadiopharmaceuticals capable of targeting the fibroblast activation protein have become widely utilized in the research realm as well as...
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Membrane-based microfluidic solvent extraction of Ga-68 from aqueous Zn solutions: towards an automated cyclotron production loop
BackgroundThe radionuclide Ga-68 is commonly used in nuclear medicine, specifically in positron emission tomography (PET). Recently, the interest in...
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Penetration Profiles of Four Topical Antifungals in Mycotic Human Toenails Quantified by Matrix-Assisted Laser Desorption Ionization–Fourier Transform Ion Cyclotron Resonance Imaging
IntroductionOnychomycosis is a fungal infection of the nails that can be challenging to treat. Here, matrix-assisted laser desorption...
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Penetration Profile of Terbinafine Compared to Amorolfine in Mycotic Human Toenails Quantified by Matrix-Assisted Laser Desorption Ionization–Fourier Transform Ion Cyclotron Resonance Imaging
IntroductionAmorolfine 5% lacquer is an established topical treatment for fungal infection of the nails. The success of topical therapy for...
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Cyclotron production and radiochemical purification of terbium-155 for SPECT imaging
BackgroundTerbium-155 [T 1/2 = 5.32 d, Eγ = 87 keV (32%) 105 keV (25%)] is an interesting radionuclide suitable for single photon emission computed...
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Current status on cyclotron facilities and related infrastructure supporting PET applications in Latin America and the Caribbean
This review presents the results of a survey conducted by the International Atomic Energy Agency on cyclotrons and related infrastructure used for...
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Cyclotron production of 225Ac from an electroplated 226Ra target
PurposeWe demonstrate cyclotron production of high-quality 225 Ac using an electroplated 226 Ra target.
Methods226 Ra was extracted from legacy Ra...
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Feasibility of exercise treadmill 13N-ammonia positron emission tomography myocardial perfusion imaging using an off-site cyclotron
BackgroundMyocardial perfusion imaging with treadmill exercise nitrogen-13 ( 13 N)-ammonia positron emission tomography (PET) presents a logistical...
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Cyclotron-based production of 68Ga, [68Ga]GaCl3, and [68Ga]Ga-PSMA-11 from a liquid target
PurposeTo optimize the direct production of 68 Ga on a cyclotron, via the 68 Zn(p,n) 68 Ga reaction using a liquid cyclotron target. We Investigated the...
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What is the potential impact of the IsoDAR cyclotron on radioisotope production: a review
The IsoDAR collaboration is develo** a high-current cyclotron for a neutrino search experiment. Designed to deliver 10 mA of 60 MeV protons, the...
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Multi-curie production of gallium-68 on a biomedical cyclotron and automated radiolabelling of PSMA-11 and DOTATATE
BackgroundWith increasing clinical demand for gallium-68, commercial germanium-68/gallium-68 ([ 68 Ge]Ge/[ 68 Ga]Ga) generators are incapable of...
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Good practices for 68Ga radiopharmaceutical production
BackgroundThe radiometal gallium-68 ( 68 Ga) is increasingly used in diagnostic positron emission tomography (PET), with 68 Ga-labeled...
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A Brief History of Nuclear Medicine Physics, Instrumentation, and Data Sciences in Korea
We review the history of nuclear medicine physics, instrumentation, and data sciences in Korea to commemorate the 60 th anniversary of the Korean...
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Radiation Safety Guide for Nuclear Medicine Professionals
The book covers all the radiation safety aspects while working with unsealed radionuclides. Radiation safety plays a significant role in routine...
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Production of the PET radionuclide 61Cu via the 62Ni(p,2n)61Cu nuclear reaction
BackgroundThere are only a handful of true theranostic matched pairs, and in particular the theranostic radiocopper trio 61 Cu, 64 Cu and 67 Cu, for...
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Good practices for the automated production of 18F-SiFA radiopharmaceuticals
BackgroundThe positron emitting isotope fluorine-18 ( 18 F) possesses almost ideal physicochemical properties for the development of radiotracers for...
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Hybrid PET/MR Neuroimaging A Comprehensive Approach
This book serves as a reference and comprehensive guide for PET/MR neuroimaging. The field of PET/MR is rapidly evolving, however, there is no...
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Development of new copper-64 labeled rhodamine: a potential PET myocardial perfusion imaging agent
BackgroundMyocardial perfusion imaging (MPI) is one of the most commonly performed investigations in nuclear medicine procedures. Due to the longer...
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Targeted α-therapy using astatine (211At)-labeled PSMA1, 5, and 6: a preclinical evaluation as a novel compound
PurposeTargeted α-therapy (TAT) for prostate-specific membrane antigen (PSMA) is a promising treatment for metastatic castration-resistant prostate...