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The 2023 Türkiye-Syria earthquakes: analysis of pediatric victims with crush syndrome and acute kidney Injury
BackgroundOn February 6th, 2023, two consecutive earthquakes struck southeastern Türkiye with magnitudes of 7.7 and 7.6, respectively. This study...
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Effect of necrostatin-1 on sciatic nerve crush injury in rat models
BackgroundNecrostatin-1 (Nec-1) is an inhibitor of the receptor interacting protein (RIP)1 kinase, which acts as an inhibitor of necroptosis, a...
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Remote ischemic postconditioning protects against crush-induced acute kidney injury via down-regulation of apoptosis and senescence
BackgroundAcute renal failure due to crush syndrome is one of the leading causes of death in disasters. Ischemic Postconditioning (IPC) is a...
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Is the renal score predictive for kidney replacement therapy in pediatric patients with crush syndrome?
BackgroundCrush syndrome (CS) is a systemic condition resulting from rhabdomyolysis caused by prolonged pressure on muscle tissue. It is estimated...
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Park7 protects retinal ganglion cells and promotes functional preservation after optic nerve crush via regulation of the Nrf2 signaling pathway
PurposeWe aim to investigate the effect of Park7 on mice RGC survival and function following optic nerve crush (ONC), and to explore its potential...
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Raman spectroscopy and sciatic functional index (SFI) after low-level laser therapy (LLLT) in a rat sciatic nerve crush injury model
Axonotmesis causes sensorimotor and neurofunctional deficits, and its regeneration can occur slowly or not occur if not treated appropriately....
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Buyang Huanwu Decoction Ameliorates Damage of Erectile Tissue and Function Following Bilateral Cavernous Nerve Injury
ObjectiveTo verify the effect of Buyang Huanwu Decoction (BHD) in ameliorating erectile dysfunction (ED) after radical prostatectomy (RP).
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Anti-high-mobility group box-1 (HMGB1) mediates the apoptosis of alveolar epithelial cells (AEC) by receptor of advanced glycation end-products (RAGE)/c-Jun N-terminal kinase (JNK) pathway in the rats of crush injuries
ObjectivesThe lung injury is often secondary to severe trauma. In the model of crush syndrome, there may be secondary lung injury. We hypothesize...
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Characteristics of cytokines in the sciatic nerve stumps and DRGs after rat sciatic nerve crush injury
BackgroundCytokines are essential cellular modulators of various physiological and pathological activities, including peripheral nerve repair and...
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Traumatic muscle injury
Traumatic muscle injury represents a collection of skeletal muscle pathologies caused by trauma to the muscle tissue and is defined as damage to the...
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Research progress of astragaloside IV in treating acute kidney injury
Acute kidney injury (AKI) is one of the most common clinical critical illnesses, with decreased glomerular filtration rate, retention of nitrogen...
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β1-Blocker improves survival and ventricular remodelling in rats with lethal crush injury
BackgroundCrush injury/crush syndrome (CI/CS) is the second most common cause of death during earthquakes. Most studies of CI/CS have mainly focused...
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Evaluation of canine adipose-derived mesenchymal stem cells for neurological functional recovery in a rat model of traumatic brain injury
BackgroundTraumatic brain injury (TBI) is a common condition in veterinary medicine that is difficult to manage.Veterinary regenerative therapy based...
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Nerve Injury Following Regional Nerve Block: A Literature Review of Its Etiologies, Risk Factors, and Prevention
Purpose of ReviewPostoperative nerve injury after nerve block is complex and multifactorial. The mechanisms, etiologies, and risk factors are...
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Tourniquet use following blast-associated complex lower limb injury and traumatic amputation promotes end organ dysfunction and amplified heterotopic ossification formation
BackgroundTraumatic heterotopic ossification (tHO) is characterized by ectopic bone formation in extra-skeletal sites leading to impaired wound...
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Military-related mild traumatic brain injury: clinical characteristics, advanced neuroimaging, and molecular mechanisms
Mild traumatic brain injury (mTBI) is a significant health burden among military service members. Although mTBI was once considered relatively benign...
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The effect of a silicone sheet on sciatic nerve healing in rats
BackgroundFibrosis occurs during the healing process after nerve injury. Extraneural fibrosis occurs around the epineural sheath. Intraneural...
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Temporal and spatial cellular and molecular pathological alterations with single-cell resolution in the adult spinal cord after injury
Spinal cord injury (SCI) involves diverse injury responses in different cell types in a temporally and spatially specific manner. Here, using...
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Assessment of outer retinal thickness and function in mice after experimental optic nerve trauma
BackgroundOptic nerve trauma caused by crush injury is frequently used for investigating experimental treatments that protect retinal ganglion cells...
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Molecular mechanisms of exercise contributing to tissue regeneration
Physical activity has been known as an essential element to promote human health for centuries. Thus, exercise intervention is encouraged to battle...
