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Modelling count, bounded and skewed continuous outcomes in physical activity research: beyond linear regression models
BackgroundInference using standard linear regression models (LMs) relies on assumptions that are rarely satisfied in practice. Substantial...
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Influencing factors of multiple adverse outcomes among schizophrenia patients using count regression models: a cross-sectional study
BackgroundSchizophrenia patients have increased risks of adverse outcomes, including violent crime, aggressiveness, and suicide. However, studies of...
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Comparison of estimation methods and sample size calculation for parameter-driven interrupted time series models with count outcomes
Interrupted time series (ITS)—a quasi-experimental design—is often used to evaluate the effectiveness of a health policy intervention. When the...
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Socioeconomic Status and CD4 Count Among People with HIV Who Inject Drugs in St. Petersburg, Russia
Lack of access to resources is a “fundamental cause” of poor HIV outcomes across the care cascade globally and may have the greatest impact on groups...
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White Blood Cell Count Predicts Mortality in Patients with Spontaneous Intracerebral Hemorrhage
BackgroundThe association between white blood cell (WBC) counts and mortality in patients with intracerebral hemorrhage (ICH) has not been...
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Enhancing pneumonia prognosis in the emergency department: a novel machine learning approach using complete blood count and differential leukocyte count combined with CURB-65 score
BackgroundPneumonia poses a major global health challenge, necessitating accurate severity assessment tools. However, conventional scoring systems...
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Leukocyte count and the risk of adverse outcomes in patients with HFpEF
BackgroundInflammation is a key feature of heart failure including HFpEF. The leukocyte count is a marker of inflammation that is widely used in...
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Optimizing pregnancy outcomes in intrauterine insemination cycles by stratifying pre-wash total motile count and patient-specific factors: a patient counseling tool
PurposeThe purpose of this study is to clarify which pre-wash total motile count are associated with improved clinical pregnancy rate (CPR) and live...
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Use of days alive without life support and similar count outcomes in randomised clinical trials – an overview and comparison of methodological choices and analysis methods
BackgroundDays alive without life support (DAWOLS) and similar outcomes that seek to summarise mortality and non-mortality experiences are...
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Low platelet count at diagnosis of anti-neutrophil cytoplasmic antibody-associated vasculitis is correlated with the severity of disease and renal prognosis
Antineutrophil cytoplasmic antibody-associated vasculitis (AAV) is an autoimmune disease that involves inflammation of blood vessels. There is...
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Early decrease in blood lymphocyte count is associated with poor prognosis in COVID-19 patients: a retrospective cohort study
BackgroundPrevious studies have declared that baseline lymphocyte count is associated with COVID-19-related death. However, whether dynamic...
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Pediatric acute myeloid leukemia and hyperleukocytosis with WBC count greater than 50 × 109/L
BackgroundAcute myeloid leukemia (AML) and hyperleukocytosis have an unfavorable prognosis, but the impact of hyperleukocytosis on the prognosis of...
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A novel correction method for modelling parameter-driven autocorrelated time series with count outcome
BackgroundCount time series (e.g., daily deaths) are a very common type of data in environmental health research. The series is generally...
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Prognostic and predictive value of examined lymph node count in stage III colorectal cancer: a population based study
BackgroundThe role of tumor-draining lymph nodes in the progression of malignant tumors, including stage III colorectal cancer (CRC), is critical....
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Association of a decreased platelet count with poor survival in patients with adult secondary hemophagocytic lymphohistiocytosis
We aimed to examine the association between baseline platelet count (PLT) and the prognosis of adult secondary hemophagocytic lymphohistiocytosis...
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Mediation and longitudinal analysis to interpret the association between clozapine pharmacokinetics, pharmacogenomics, and absolute neutrophil count
Clozapine is effective at reducing symptoms of treatment-resistant schizophrenia, but it can also induce several adverse outcomes including...
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Significance of absolute neutrophil count before allogeneic hematopoietic stem cell transplantation in adult patients with aplastic anemia
The impact of absolute neutrophil count (ANC) before allogenic hematopoietic stem cell transplantation (HSCT) on the outcomes for patients with...
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Clinical implications of peripheral eosinophil count at diagnosis in patients newly diagnosed with microscopic polyangiitis and granulomatosis with polyangiitis
BackgroundThis study investigated the clinical implications of peripheral eosinophil count at diagnosis in estimating cross-sectional antineutrophil...
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Efficacy of Biologics in Severe, Uncontrolled Asthma Stratified by Blood Eosinophil Count: A Systematic Review
IntroductionRandomized controlled trials (RCTs) of biologics in patients with severe, uncontrolled asthma have shown differential results by baseline...
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Online COVID-19 diagnosis prediction using complete blood count: an innovative tool for public health
BackgroundCOVID-19, caused by SARS-CoV-2, presents distinct diagnostic challenges due to its wide range of clinical manifestations and the...
