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Mucus Transpiration as the Basis for Chronic Cough and Cough Hypersensitivity
Chronic cough is characterized by a state of cough hypersensitivity. We analyze the process of transpiration, by which water appears to evaporate...
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Drugs Targeting Cough Receptors: New Therapeutic Options in Refractory or Unexplained Chronic Cough
Refractory chronic cough is a disabling disease with very limited therapeutic options. A better understanding of cough pathophysiology has led to the...
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Cough hypersensitivity and chronic cough
Chronic cough is globally prevalent across all age groups. This disorder is challenging to treat because many pulmonary and extrapulmonary conditions...
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Feasibility and Utility of a Smartphone Application-Based Longitudinal Cough Monitoring in Chronic Cough Patients in a Real-World Setting
PurposeThis study evaluated the feasibility and utility of longitudinal cough frequency monitoring with the Hyfe Cough Tracker, a mobile application...
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Chronic cough: more than just a persistent cough: a systematic literature review to understand the impact of chronic cough on quality of life
PurposeChronic cough (CC), defined as a cough persisting ≥ 8 weeks, can have a substantial negative impact on health-related quality of life (HRQoL)....
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Cough Response to High-Dose Inhaled Corticosteroids in Patients with Chronic Cough and Fractional Exhaled Nitric Oxide Levels ≥ 25 ppb: A Prospective Study
This study aimed to investigate the effects of high-dose inhaled corticosteroids (ICS) on chronic cough patients with elevated fractional exhaled...
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Investigating the risk of reintubation by cough force assessment using cough peak expiratory flow: a single-center observational pilot study
BackgroundNo objective indicator exists for evaluating cough strength during extubation of tracheally intubated patients. This study aimed to...
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How often do healthy people cough?
Objective cough frequency has been reported in several respiratory conditions but the amount that healthy individuals cough daily is unclear....
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Cough desensitization treatment for patients with refractory chronic cough: results of a second pilot randomized control trial
ObjectiveThe purpose of this study was to collect pilot efficacy data on a novel treatment for refractory chronic cough (RCC), which we call cough...
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Validation and Meaningful Change Thresholds for an Objective Cough Frequency Measurement in Chronic Cough
PurposeObjective cough frequency is used to assess efficacy of chronic cough (CC) treatments. The objective of this study was to explore the...
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Recurrent Cough in the Elderly: A Forgotten Entity
IntroductionRecurrent cough is little researched in adults. We investigated the prevalence, risk factors, and consequences of recurrent cough, and...
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Primary Cough Headache
Purpose of ReviewIn this review article, we summarize the most recent findings and observations in patients experiencing primary cough headache.
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The Therapeutic Landscape in Chronic Cough
In recent years, there has been a substantial increase in the development of antitussive therapies and the first new therapy, gefapixant has been...
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Current cough and sputum assessed by the cough and sputum assessment-questionnaire (CASA-Q) is associated with quality of life impairment in cystic fibrosis
BackgroundCough and sputum are major symptoms in cystic fibrosis (CF) that contribute to the impairment of quality of life.
MethodsThis prospective...
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The Severity of Chronic Cough Diary (SCCD): development and content validation of a novel patient-reported outcome instrument for evaluating the symptom experience of chronic cough
BackgroundRefractory chronic cough (RCC), a cough lasting longer than 8 weeks with an unexplained underlying etiology and unresponsive to...
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Risk factors for cough after pulmonary resection
BackgroundTo investigate the risk factors for cough after pulmonary resection.
MethodsThe PubMed, Embase, Web of Science, ClinicalTrials.gov, and...
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Cough Characteristics and Healthcare Journeys of Chronic Cough Patients in Community-Based Populations in South Korea and Taiwan
PurposeThis study aimed to understand the cough characteristics and health journeys among community-based chronic cough (CC) patients, and their...
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Narrative Review of the Mechanisms and Treatment of Cough in Asthma, Cough Variant Asthma, and Non-asthmatic Eosinophilic Bronchitis
Chronic cough is a debilitating condition affecting 10–12% of the general population and is one of the leading causes for referral to secondary care....
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Cough RIB Fracture: An Uncommon Upper Respiratory Cause
Cough is a whole-sole dynamic housekeeper of the airways. Although a run-of-the-mill symptom, chronic cough frequently forces the patient to seek...
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A Primer on Hypotussic Cough: Mechanisms and Assessment
Purpose of ReviewThis narrative review introduces key elements of cough neural control, function, dysfunction, and measurement for physicians and...
