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Motor performance and functional connectivity between the posterior cingulate cortex and supplementary motor cortex in bipolar and unipolar depression
Although implicated in unsuccessful treatment, psychomotor deficits and their neurobiological underpinnings in bipolar (BD) and unipolar (UD)...
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Interoceptive training impacts the neural circuit of the anterior insula cortex
Interoception is the perception of afferent information that arises from anywhere and everywhere within the body. Recently, interoceptive accuracy...
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Dorsal peduncular cortex activity modulates affective behavior and fear extinction in mice
The medial prefrontal cortex (mPFC) is critical to cognitive and emotional function and underlies many neuropsychiatric disorders, including mood,...
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Intoxication due to Δ9-tetrahydrocannabinol is characterized by disrupted prefrontal cortex activity
Neural states of impairment from intoxicating substances, including cannabis, are poorly understood. Cannabinoid 1 receptors, the main target of...
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Roles of the medial and lateral orbitofrontal cortex in major depression and its treatment
We describe evidence for dissociable roles of the medial and lateral orbitofrontal cortex (OFC) in major depressive disorder (MDD) from structure,...
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Single-cell RNA-seq reveals the role of YAP1 in prefrontal cortex microglia in depression
BackgroundDepression is a complex mood disorder whose pathogenesis involves multiple cell types and molecular pathways. The prefrontal cortex, as a...
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Altered brain metabolism in frontotemporal dementia and psychiatric disorders: involvement of the anterior cingulate cortex
BackgroundBehavioural symptoms and frontotemporal hypometabolism overlap between behavioural variant of frontotemporal dementia (bvFTD) and primary...
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Reactivation of encoding ensembles in the prelimbic cortex supports temporal associations
Fear conditioning is encoded by strengthening synaptic connections between the neurons activated by a conditioned stimulus (CS) and those activated...
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A disinhibitory microcircuit of the orbitofrontal cortex mediates cocaine preference in mice
Both clinical and animal studies showed that the impaired functions of the orbitofrontal cortex (OFC) underlie the compulsive drug-seeking behavior...
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A state-of-the-art review on deep learning for estimating eloquent cortex from resting-state fMRI
Deep learning algorithms have greatly improved our ability to estimate eloquent cortex regions from resting-state brain scans for patients about to...
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Deciphering the functional role of insular cortex stratification in trigeminal neuropathic pain
Trigeminal neuropathic pain (TNP) is a major concern in both dentistry and medicine. The progression from normal to chronic TNP through activation of...
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A paraventricular thalamus to insular cortex glutamatergic projection gates “emotional” stress-induced binge eating in females
It is well-established that stress and negative affect trigger eating disorder symptoms and that the brains of men and women respond to stress in...
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Smoking, tobacco dependence, and neurometabolites in the dorsal anterior cingulate cortex
Cigarette smoking has a major impact on global health and morbidity, and positron emission tomographic research has provided evidence for reduced...
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Food stimuli decrease activation in regions of the prefrontal cortex related to executive function: an fNIRS study
PurposeOverweight/obese individuals show impairments in executive functions such as inhibitory control. However, the neural mechanisms underlying...
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Astrocytes modulate cerebral blood flow and neuronal response to cocaine in prefrontal cortex
Cocaine affects both cerebral blood vessels and neuronal activity in brain. Cocaine can also disrupt astrocytes, which modulate neurovascular...
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Modulatory effect of exercise on reactive astrocytes in the somatosensory cortex of epileptic rats
BackgroundAstrocytes as the most abundant brain cells play a variety of critical roles in neuroplasticity and normal brain function. Many epileptic...
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Fear extinction rescuing effects of dopamine and L-DOPA in the ventromedial prefrontal cortex
The ventromedial prefrontal cortex (vmPFC; rodent infralimbic cortex (IL)), is posited to be an important locus of fear extinction-facilitating...
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Effects of primary motor cortex noninvasive brain stimulation on post-stroke aphasia: a narrative review
Aphasia is one of the most debilitating impairments after stroke, significantly affecting patients’ comprehension, communication, functional...
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2D Shear wave elastography for evaluation of renal cortex and medulla: stiffness values in healthy children
PurposeTo evaluate renal cortical and medullary stiffness using 2D Shear-wave elastography (SWE) in healthy children.
MethodsIn this IRB approved...
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Is Posterior Femoral Neck Cortex an Obstacle in Achieving Sagittal Plane Balance of Uncemented Straight Femoral Stem?
Summary of Background DataThere is a paucity of the literature that aims to improve sagittal plane balance of femoral stem in hip arthroplasty. We...