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Identifying common core outcome domains from core outcome sets of musculoskeletal conditions: protocol for a systematic review
BackgroundCore outcome sets (COSs) aim to reduce outcome heterogeneity in clinical practice and research by suggesting a minimum number of...
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A protocol for develo** core outcome sets for laparoscopic hiatal hernia repair
BackgroundHiatal hernias negatively damage patients’ health and life quality. Laparoscopic hiatal hernia repair is currently the gold standard for...
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The Importance of Grey and Qualitative Literature in Develo** Domestic Violence and Abuse and Child Maltreatment Core Outcome Sets: A Brief Report
PurposeCore Outcome Sets (COS) are agreed sets of outcomes to be used in all trials that evaluate the effect of interventions. This report considers...
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Development of core outcome sets of Food for Special Medical Purposes designed for type 2 diabetes mellitus: a study protocol
BackgroundThe Chinese government stipulates all food for special medical purposes (FSMP) designed for specific diseases to be tested in clinical...
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Core outcome sets in clinical laser research: how better evidence can be better for patients
Core outcome sets, or the minimum sets of outcomes that would be used in all clinical studies of a given disease or condition, have the potential to...
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Synthesizing Core Outcome Sets for outcomes research in cohort studies: a systematic review
BackgroundLife course studies are designed to “collect once, use multiple times” for observational and, increasingly, interventional research. Core...
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A Foundation for Patient-Centered Core Impact Sets: Key Learnings from Past and Existing Approaches
Despite growing commitment to patient centricity, challenges persist in consistently identifying the impacts of disease and/or treatment that...
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Develo** an Outcome Measures in Rheumatology (OMERACT) Core set of Outcome Measures for FOot and ankle disorders in RheumaTic and musculoskeletal diseases (COMFORT): core domain set study protocol
BackgroundFoot and ankle involvement is common in rheumatic and musculoskeletal diseases (RMDs). High-quality evidence is lacking to determine the...
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A survey of knowledge, perceptions and use of core outcome sets among clinical trialists
BackgroundCore outcome sets (COS) are standardised sets of outcomes, which represent the minimum outcomes that should be measured and reported in...
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Outcome reporting in randomized controlled trials (RCTs) on the pharmacological management of idiopathic overactive bladder (OAB) in women; a systematic review for the development of core outcome sets (COS)
Introduction and hypothesisEvidence on OAB management remains suboptimal and methodological limitations in randomized control trials (RCTs) affect...
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Outcome selection for tissue-agnostic drug trials for immune-mediated inflammatory diseases: a systematic review of core outcome sets and regulatory guidance
BackgroundTissue-agnostic drug development provides a paradigm shift in precision medicine and requires innovative trial designs. However, outcome...
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Core Outcome Sets (COS) related to pregnancy and childbirth: a systematic review
BackgroundSystematic reviews often conclude low confidence in the results due to heterogeneity in the reported outcomes. A Core Outcome Set (COS) is...
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Develo** a core outcome set for acetabular fractures: a systematic review protocol
BackgroundClinical trials investigating acetabular fractures are heterogeneous in their investigated outcomes and their corresponding measurements....
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The development of a core outcome set for studies of pregnant women with multimorbidity
BackgroundHeterogeneity in reported outcomes can limit the synthesis of research evidence. A core outcome set informs what outcomes are important and...
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The methodological quality of systematic reviews regarding the Core Outcome Set (COS) development
BackgroundThe Core Outcome Measures in Effectiveness Trials (COMET) working group proposed core outcome sets (COS) to address the heterogeneity in...
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Vitiligo International Task force for an Agreed List of core data (VITAL): study protocol of a vitiligo core outcome set (COS) and contextual factors for clinical trials, registries, and clinical practice
BackgroundThere is a lack of consensus related to the collection of standardized data for individuals with vitiligo enrolled in clinical trials and...
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Hospital-to-home transitions for children with medical complexity: part 2—a core outcome set
Appropriate outcome measures as part of high-quality intervention trials are critical to advancing hospital-to-home transitions for Children with...
