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Estimating conditional vaccine effectiveness
Vaccine effectiveness for COVID-19 is typically estimated for different outcomes that often are hierarchical in severity (e.g. any documented...
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Conditional versus non-conditional incentives to maximise return of participant completed questionnaires in clinical trials: a cluster randomised study within a trial
BackgroundHigh participant retention enhances the validity of clinical trials. A monetary incentive can increase retention, but it is not known if...
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Conditional Funding Recommendations for Drugs in Canada: A Cross-Sectional Analysis
Background and ObjectiveBefore listing by drug plans, new drugs that receive regulatory bodies’ approval are assessed by the Health Technology...
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The formation mechanism of primary health care team effectiveness : a qualitative comparative analysis research
BackgroundTeam-based care is an essential part of primary health care (PHC), and its team service delivery process is a systematic one involving...
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HTA Barriers for Conditional Approval Drugs
BackgroundConditional approval pathways facilitate accelerated marketing authorisation based on immature clinical evidence for drugs that address an...
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Effectiveness of conditional cash transfers, subsidized child care and life skills training on adolescent mothers’ schooling, sexual and reproductive health, and mental health outcomes in Burkina Faso and Malawi: the PROMOTE Project pilot randomized controlled trial protocol
IntroductionGirls’ and women’s health as well as social and economic wellbeing are often negatively impacted by early childbearing. In many parts of...
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Vaccine effectiveness against emerging COVID-19 variants using digital health data
BackgroundParticipatory surveillance of self-reported symptoms and vaccination status can be used to supplement traditional public health...
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Cost-effectiveness and feasibility of conditional economic incentives and motivational interviewing to improve HIV health outcomes of adolescents living with HIV in Anambra State, Nigeria
BackgroundIn sub-Saharan Africa, there is increasing mortality and morbidity of adolescents due to poor linkage, retention in HIV care and adherence...
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Estimating sensitivity and specificity of diagnostic tests using latent class models that account for conditional dependence between tests: a simulation study
BackgroundLatent class models are increasingly used to estimate the sensitivity and specificity of diagnostic tests in the absence of a gold...
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Cost-effectiveness of differentiated care models that incorporate economic strengthening for HIV antiretroviral therapy adherence: a systematic review
BackgroundThere is some evidence that differentiated service delivery (DSD) models, which use a client-centered approach to simplify and increase...
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Conditional survival analysis and dynamic survival prediction for intracranial solitary-fibrous tumor/hemangiopericytoma
BackgroundAs the form of World Health Organization Central Nervous System (WHO CNS) tumor classifications is updated, there is a lack of research on...
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The effectiveness and cost-effectiveness of a group domestic abuse perpetrator programme: protocol for a randomised controlled trial
BackgroundIn contrast to evidence for interventions supporting victim/survivors of domestic violence and abuse (DVA), the effectiveness of...
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Transporting Comparative Effectiveness Evidence Between Countries: Considerations for Health Technology Assessments
Internal validity is often the primary concern for health technology assessment agencies when assessing comparative effectiveness evidence. However,...
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Effectiveness of the booster dose of inactivated COVID-19 vaccine against Omicron BA.5 infection: a matched cohort study of adult close contacts
BackgroundAlthough COVID-19 vaccines and their booster regimens protect against symptomatic infections and severe outcomes, there is limited evidence...
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Rudi Kundini, Pamoja Kundini (RKPK): study protocol for a hybrid type 1 randomized effectiveness-implementation trial using data science and economic incentive strategies to strengthen the continuity of care among people living with HIV in Tanzania
BackgroundEconomic incentives can improve clinical outcomes among in-care people living with HIV (PLHIV), but evidence is limited for their...
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Cost-effectiveness of TB diagnostic technologies in Ethiopia: a modelling study
BackgroundTuberculosis (TB) is a major threat to public health, particularly in countries where the disease is highly prevalent, such as Ethiopia....
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Cost-Effectiveness Analysis of Etranacogene Dezaparvovec Versus Extended Half-Life Prophylaxis for Moderate-to-Severe Haemophilia B in Germany
Background and ObjectiveHaemophilia B is a rare genetic disease that is caused by a deficiency of coagulation factor IX (FIX) in the blood and leads...
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Utilizing an artificial intelligence framework (conditional generative adversarial network) to enhance telemedicine strategies for cancer pain management
BackgroundThe utilization of artificial intelligence (AI) in healthcare has significant potential to revolutionize the delivery of medical services,...
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ODs with a positive TPR conclusion, not subject to a conditional approval, and approved without requiring a PASS would be more likely to be reimbursed in Spain
BackgroundThe present study aims to assess clinical and regulatory variables that would influence pricing and reimbursement (P&R) decisions for...
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Effectiveness and Respiratory Adverse Events Following Inactivated and mRNA COVID-19 Vaccines in Patients with COPD and Asthma: A Chinese Population-Based Study
IntroductionEffectiveness and respiratory adverse events following coronavirus disease-2019 (COVID-19) vaccines have not been well investigated in...
