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Application of analgesics in emergency services in Germany: a survey of the medical directors
BackgroundTreatment of acute pain is an essential element of pre-hospital care for injured and critically ill patients. Clinical studies indicate the...
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Nociceptin Receptor-Related Agonists as Safe and Non-addictive Analgesics
As clinical use of currently available opioid analgesics is often impeded by dose-limiting adverse effects, such as abuse liability and respiratory...
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Outcomes of hip fracture treatment with intravenous morphine and with other analgesics: postoperative analgesic medical expense, severity of pain and hospitalisation—a retrospective study
AimsThis study compares the postoperative medical costs and outcomes of hip fracture patients treated with intravenous (IV) versus other analgesics...
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Use of prescribed analgesics before and after exercise therapy and patient education in patients with knee or hip osteoarthritis
The aim of this study was to investigate utilisation patterns of prescribed analgesics before, during, and after an exercise therapy and patient...
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A nationwide study on consumption of opioid analgesics in Iran from 2000 to 2018
BackgroundOpioid analgesics play a unique role in pain management. National opioid consumption studies could provide indirect evidence of pain...
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The Opioid Analgesic Reduction Study (OARS)—a comparison of opioid vs. non-opioid combination analgesics for management of post-surgical pain: a double-blind randomized clinical trial
BackgroundEveryday people die unnecessarily from opioid overdose-related addiction. Dentists are among the leading prescribers of opioid analgesics....
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Prescription patterns of analgesics in cancer patients with bone metastases in Japan: a retrospective database study
BackgroundReal-world data on optimal cancer pain management remain scarce. We describe prescription patterns of analgesics in Japanese cancer...
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The impact of the COVID-19 pandemic on community prescription of opioid and antineuropathic analgesics for cancer patients in Wales, UK
PurposePublic health measures instituted at the onset of the COVID-19 pandemic in the UK in 2020 had profound effects on the cancer patient pathway....
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Changes in hospital consumption of opioid and non-opioid analgesics after colorectal endometriosis surgery
The aim of this study was to analyze postoperative consumption of analgesics during hospitalization following colorectal surgery for endometriosis....
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Prescribing Pattern of Analgesics in Colombia. Are there Differences between Capital Cities and Municipalities? A Cross-Sectional Study
BackgroundAnalgesics provide multiple clinical benefits but they are not without risks.
ObjectiveThe aim of this study was to compare the outpatient...
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Comparison of Efficacy and Safety of Transdermal Buprenorphine Patch and Conventional Analgesics in Intra-capsular Femur Neck Fracture Post Hemiarthroplasty
BackgroundOne of the most common fractures in the elderly population is a fracture of the neck of femur. Effective post-operative analgesia is a...
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Associations between over-the-counter analgesics usage and symptoms of anxiety and depression in adolescents: a network analysis
BackgroundThe use of over-the-counter analgesics (OTCA) is common among adolescents and has been linked with increased symptoms of anxiety and...
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A Survey of the Incidence of Constipation in Patients with Chronic Non-cancer Pain Using Opioid Analgesics in Japan
IntroductionAlthough opioids have potent analgesic properties, their use is associated with side effects, including opioid-induced constipation...
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Paracetamol Combination Therapy for Back Pain and Osteoarthritis: A Systematic Review and Meta-Analyses
Background and ObjectiveAlthough paracetamol (acetaminophen) combined with other analgesics can reduce pain intensity in some pain conditions, its...
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Comparing the efficacy of intravenous morphine versus ibuprofen or the combination of ibuprofen and acetaminophen in patients with closed limb fractures: a randomized clinical trial
IntroductionThis study aims to investigate the effectiveness of intravenous ibuprofen or intravenous ibuprofen plus acetaminophen compared to...
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Effect of an intravenous acetaminophen/ibuprofen fixed-dose combination on postoperative opioid consumption and pain after video-assisted thoracic surgery: a double-blind randomized controlled trial
BackgroundVideo-assisted thoracoscopic surgery (VATS) often induces significant postoperative pain, potentially leading to chronic pain and decreased...
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Impact of opioid analgesics on the efficacy of immune checkpoint inhibitors in a lung cancer population
ObjectiveA retrospective clinical study was conducted to compare the prognosis between the opioid analgesic (OA) treated and OA-untreated groups and...
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Killing pain?: a population-based registry study of the use of prescription analgesics, anxiolytics, and hypnotics among all children, adolescents and young adults in Norway from 2004 to 2019
The ongoing opioid epidemic has been a global concern for years, increasingly due to its heavy toll on young people’s lives and prospects. Few...
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Perioperative Analgesics and Anesthesia as Risk Factors for Postoperative Chronic Opioid Use in Patients Undergoing Total Knee Arthroplasty: A Retrospective Cohort Study Using Japanese Hospital Claims Data
BackgroundPatients with chronic postsurgical pain are commonly prescribed opioids chronically because of refractory pain although chronic opioid use...
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Increased use of analgesics in midlife women but no association with mental stress: observations from the Prospective Population Study of Women in Gothenburg
BackgroundThe study is part of the ongoing Prospective Population Study of Women in Gothenburg, Sweden, initiated in 1968–1969 with the aim of...
