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A case report of two instances of colorectal hepatoid adenocarcinoma, accompanied by a comprehensive literature review
ObjectiveThe study aimed to explore the clinical and pathological characteristics, survival outcomes, and prognostic factors of colorectal hepatoid...
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Lymph node ratio is a more robust predictor of overall survival than N stage in stage III colorectal adenocarcinoma
BackgroundLymph node ratio (LNR) may offer superior prognostic stratification in colorectal adenocarcinoma compared with N stage. However, candidate...
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Incidence and survival of adenocarcinoma with mixed subtypes in patients with colorectal cancer
BackgroundLimited attention was paid to adenocarcinoma with mixed subtypes (AM) of the colon and rectum due to its low incidence. This study aims to...
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Tumoricidal properties of thymoquinone on human colorectal adenocarcinoma cells via the modulation of autophagy
Colorectal cancer (CRC) is deadly anaplastic changes in the gastrointestinal tract with high-rate mortality. In recent years, the application of...
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The potential therapeutic effect of klotho on cell viability in human colorectal adenocarcinoma HT-29 cells
Klotho is an anti-aging, anti-inflammator, and anti-oxidative protein and has been shown to important role in tumorigenesis, proliferation, survival,...
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Identification and validation of a novel six-gene signature based on mucinous adenocarcinoma-related gene molecular ty** in colorectal cancer
Background and objectivesColorectal mucinous adenocarcinoma (MAC) is a particular pathological type that has yet to be thoroughly studied. This study...
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Colorectal adenocarcinoma in Uganda: are right-sided and left-sided colon cancers two distinct disease entities?
IntroductionIn Western countries, right-sided colon cancers (RSCC) present at an older age and advanced stage. Researchers believe that there is a...
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Prognosis of carcinoembryonic antigen (CEA) in stage I colorectal adenocarcinoma and development of a prediction model: a retrospective study based on the SEER database
BackgroundTo investigate the prognostic significance of preoperative carcinoembryonic antigen (CEA) status in stage I colorectal classical...
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The impact of SLC10A3 on prognosis and immune microenvironment in colorectal adenocarcinoma
BackgroundSLC10A3, a gene upregulated in pan-cancer, lacks full understanding regarding its prognostic implications and association with immune...
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NF-κB Activator 1 downregulation in macrophages activates STAT3 to promote adenoma-adenocarcinoma transition and immunosuppression in colorectal cancer
BackgroundAdenoma-adenocarcinoma transition is a key feature of colorectal cancer (CRC) occurrence and is closely regulated by tumor-associated...
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A case of early onset adenocarcinoma associated with colorectal polyposis with an unknown germline mutation
BackgroundTypically, in cases of adenomatous polyposis, colorectal cancer develops in the third or fourth decade of life. We report the case of a...
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Magnifying endoscopic findings of early-stage poorly differentiated colorectal adenocarcinoma: a case report
BackgroundColorectal poorly differentiated adenocarcinoma is rarely founded, especially in early-stage. Endoscopic features of early poorly...
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Synchronous “skip” facial metastases from colorectal adenocarcinoma: a case report and review of literature
BackgroundSkin metastases from colorectal adenocarcinoma are rare conditions that are metachronous in most of cases and may represent the first sign...
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Exploration of the aptitude to alleviate oxidative impairment and curb colorectal cancer manifestation by Nostoc calcicola in HT-29 adenocarcinoma cells
BackgroundMarine cyanobacteria have been known to contain several unique bioactive compounds which have different therapeutic potentials. The current...
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Prevalence and type of MMR expression heterogeneity in colorectal adenocarcinoma: therapeutic implications and reporting
Mismatch repair (MMR) immunohistochemical (IHC) evaluation has entered pathology routine practice as the first-line screening method to identify...
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Establishment and validation of a postoperative predictive model for patients with colorectal mucinous adenocarcinoma
BackgroundThe aim of this study was to develop comprehensive and effective nomograms for predicting overall survival (OS) and cancer-specific...
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The value of preoperative diagnosis of colorectal adenocarcinoma pathological T staging based on dual-layer spectral-detector computed tomography extracellular volume fraction: a preliminary study
PurposeTo investigate the value of preoperative diagnosis of colorectal adenocarcinoma (CRAC) pathological T staging based on dual-layer...
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Liver metastases of colorectal adenocarcinoma with intrahepatic biliary spread pattern: clinical manifestation and importance of immunohistochemical analysis
Liver metastases of colorectal carcinoma (LMCC) with macroscopic intrabiliary ductal involvement are a rare entity that can clinically and...
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Survival after curative resection for stage I colorectal mucinous adenocarcinoma
PurposeThe prognostic value of the mucinous adenocarcinoma histotype on the early stages especially for stage I colorectal cancer (CRC) is still...
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Colorectal adenosquamous carcinoma: genomic profiling of a rare histotype of colorectal cancer
Colorectal adenosquamous carcinoma (ASC) is exceedingly rare, comprising less than 0.1% of all colorectal malignancies, and is characterized by an...