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Recurrence of Clostridioides difficile infection and mortality in older inpatients
PurposeThe prevalence of Clostridioides difficile infection in older and frail population is extremely high and adverse outcomes, including future...
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A Systematic Review and Meta-Analysis: A Prior Appendectomy Does Not Increase the Risk of Severe Clostridioides difficile Infection or Recurrence
Background and ObjectivesThere is conflicting evidence regarding the association between a prior appendectomy and severity of Clostridioides difficile ...
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Screening for Asymptomatic Clostridioides difficile Carriage Among Hospitalized Patients: A Narrative Review
Clostridioides difficile infection (CDI) has become the most common healthcare-associated infection in the United States, with considerable...
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Clinical outcomes of clostridioides difficile infection in the very elderly
BackgroundClostridioides difficile infection (CDI) causes considerable morbidity, mortality, and economic cost. Advanced age, prolonged stay in...
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Clostridioides difficile infection in infants: a case report and literature review
BackgroundClostridioides difficile ( C. difficile ) is the major pathogen causing antibiotic-associated diarrhea. There are a variety of symptoms...
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Trends in the epidemiology of Clostridioides difficile infection in Germany
PurposesDespite reports of a declining incidence over the last decade, Clostridioides difficile infection (CDI) is still considered the most...
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SER-109 (VOWSTâ„¢): A Review in the Prevention of Recurrent Clostridioides difficile Infection
SER-109 (VOWST â„¢ ; fecal microbiota spores, live-brpk) is a live biotherapeutic product indicated to prevent the recurrence of Clostridioides difficile ...
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Clostridioides difficile Infection in Pediatric Inflammatory Bowel Disease
Purpose of ReviewChildren with inflammatory bowel disease (IBD) are at increased risk of C. difficile infection (CDI) and experience worse outcomes...
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Emerging applications of phage therapy and fecal virome transplantation for treatment of Clostridioides difficile infection: challenges and perspectives
Clostridioides difficile , which causes life-threatening diarrheal disease, is considered an urgent threat to healthcare setting worldwide. The...
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Low prevalence of Clostridioides difficile infection in acute severe ulcerative colitis: A retrospective cohort study from northern India
BackgroundThe incidence of Clostridioides difficile infection (CDI) is high in ulcerative colitis and is associated with disease flares and adverse...
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Clostridioides difficile recurrence in individuals with and without cancer: a Swedish population-based cohort study
PurposePatients with cancer are vulnerable to Clostridioides difficile infection (CDI) due to their disease, treatment and regular hospital contact,...
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Clinical prediction rule for identifying older patients with toxigenic clostridioides difficile at the time of hospital admission
BackgroundThis study aimed to develop and validate a clinical prediction rule to screen older patients at risk of being toxigenic Clostridioides...
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Capturing the environment of the Clostridioides difficile infection cycle
Clostridioides difficile (formerly Clostridium difficile ) infection is a substantial health and economic burden worldwide. Great strides have been...
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Emerging Options for the Prevention and Management of Clostridioides difficile Infection
Agents in development for the prevention or treatment of Clostridioides difficile infection can be split into three broad categories: antibiotics,...
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Optimal therapeutic recommendation for Clostridioides difficile infection in pediatric and adolescent populations: a systematic review and meta-analysis
We conducted a systematic review and meta-analysis to examine the efficacy profiles of metronidazole (MNZ) and vancomycin (VCM) in pediatric and...
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Establishment of a gnotobiotic pig model of Clostridioides difficile infection and disease
Clostridioides difficile ( C. difficile ) is a gram-positive, spore-forming, anaerobic bacterium known to be the most common cause of hospital-acquired...
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Genomic characterization of nine Clostridioides difficile strains isolated from Korean patients with Clostridioides difficile infection
BackgroundClostridioides difficile infection (CDI) is an infectious nosocomial disease caused by Clostridioides difficile , an opportunistic pathogen...
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Cost-Effectiveness Analysis of Antimicrobial Prescribing in the Treatment of Clostridioides Difficile Infection in England
BackgroundAn economic model was developed with guidance from the National Institute for Health and Care Excellence (NICE) ‘Managing Common...