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Fecal microbiota transplantation in capsules for the treatment of steroid refractory and steroid dependent acute graft vs. host disease: a pilot study
Acute graft-versus-host disease (aGvHD) is a serious complication of allogeneic hematopoietic stem-cell transplantation with limited treatment...
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Develo** diagnostic tools for canine periodontitis: combining molecular techniques and machine learning models
BackgroundDental plaque microbes play a key role in the development of periodontal disease. Numerous high-throughput sequencing studies have...
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The association of intestinal microbiota diversity and outcomes of allogeneic hematopoietic cell transplantation: a systematic review and meta-analysis
Growing evidence suggests that highly intestinal microbiota diversity modulates host inflammation and promotes immune tolerance. Several studies have...
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Leveraging the microbiome to understand clinical heterogeneity in depression: findings from the T-RAD study
Alterations in the gut microbiome have been linked to a variety of mental illnesses including anxiety and depression. This study utilized advanced...
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Evaluating Causal Effects of Gut Microbiome on Alzheimer’s Disease
BackgroundThe preceding evidence indicates a close correlation between imbalances in the gut microbiome and Alzheimer’s disease (AD), yet the direct...
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Oral bacterial composition associated with lung function and lung inflammation in a community-based Norwegian population
BackgroundThe oral cavity is the gateway to the bacteria community in the lung. Disruption of the symbiotic balance of the oral microbiota has been...
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Differential expression of adhesion molecules in sickle cell anemia and gut microbiome effect
Sickle cell anemia (SCA) causes a long-standing vascular inflammation state, leading to endothelial dysfunction and chronic overexpression of several...
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The causal impact of gut microbiota on circulating adipokine concentrations: a two-sample Mendelian randomization study
PurposeEvidence from previous experimental and observational research demonstrates that the gut microbiota is related to circulating adipokine...
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Depression and fatigue in active IBD from a microbiome perspective—a Bayesian approach to faecal metagenomics
BackgroundExtraintestinal symptoms are common in inflammatory bowel diseases (IBD) and include depression and fatigue. These are highly prevalent...
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Maternal weight, gut microbiota, and the association with early childhood behavior: the PREOBE follow-up study
Background and aimMaternal overweight and breastfeeding seem to have a significant impact on the gut microbiota colonization process, which co-occurs...
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Gut microbiota composition and function in pregnancy as determinants of prediabetes at two-year postpartum
AimsDeep metagenomics offers an advanced tool for examining the relationship between gut microbiota composition and function and the onset of...
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Metabolome and microbiome multi-omics integration from a murine lung inflammation model of bronchopulmonary dysplasia
BackgroundRespiratory tract microbial dysbiosis can exacerbate inflammation and conversely inflammation may cause dysbiosis. Dysbiotic microbiome...
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Gut microbiome and major depressive disorder: insights from two-sample Mendelian randomization
BackgroundExisting evidence suggests that alterations in the gut microbiome are closely associated with major depressive disorder (MDD). We aimed to...
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Abnormal bile acid-microbiota crosstalk promotes the development of hepatocellular carcinoma
BackgroundGut microbiota and microbe-derived metabolites are involved in the development of HCC. Bile acids (BAs) are the most important gut...
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Significant Differences in Gut Microbiota Between Irritable Bowel Syndrome with Diarrhea and Healthy Controls in Southwest China
BackgroundIrritable bowel syndrome (IBS) is a heterogeneous disease, which is closely related to environmental factors and gut microbiota.
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Analysis of incidence and risk factors of the multidrug resistant gastrointestinal tract infection in children and adolescents undergoing allogeneic and autologous hematopoietic cell transplantation: a nationwide study
The aim of this multi-center study was to evaluate the incidence, clinical course, and risk factors for bacterial multidrug-resistant (MDR)...
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A case–control study of the association between the gut microbiota and colorectal cancer: exploring the roles of diet, stress, and race
BackgroundThe gut microbiota is associated with risk for colorectal cancer (CRC), a chronic disease for which racial disparities persist with Black...
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Microbiology and postmortem interval: a systematic review
This systematic review aims to learn if and how it is possible to use the human microbiome to indicate the time elapsed after death. Articles were...
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Modulation of Gut Microbiota Through Dietary Intervention in Neuroinflammation and Alzheimer’s and Parkinson’s Diseases
Purpose of ReviewThe gut microbiota plays a crucial role in the pathogenesis of neuroinflammation and Alzheimer’s and Parkinson’s diseases. One of...
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Comparison of 16S rRNA gene sequencing microbiota among children with serological IgE-mediated food hypersensitivity
BackgroundWe hypothesized that specific food hypersensitivity (FH) in children is linked to specific gut microbiota. The aim of our study was to...