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1. Diversity in Oncology Clinical Trials: Current Landscape for Industry-Sponsored Clinical Trials in Asia

   Introduction

   There has been a growing recognition on the importance of diversity in clinical trials. Existing research has highlighted a significant...

   Dany Habr, Manmohan Singh, Roberto Uehara in Oncology and Therapy

   Article Open access 08 December 2023
   

2. Are orthopedic clinical trials representative? An analysis of race and ethnicity reported in clinical trials between 2007 and 2022

   Introduction

   Prior studies investigating the racial and ethnic representation of orthopedic trial participants have found low rates of reporting, but...

   Christian J. Hecht II, Sophia L. Friedl, ... Atul F. Kamath in Archives of Orthopaedic and Trauma Surgery

   Article 30 March 2024
   

3. Rotavirus vaccine clinical trials: a cross-sectional analysis of clinical trials registries

   Background

   Rotavirus is a primary infectious virus causing childhood diarrhoea and is associated with significant mortality in children. Three African...

   Duduzile Ndwandwe, Sinazo Runeyi, ... Charles Wiysonge in Trials

   Article Open access 17 November 2022
   

4. Advances in Clinical Cardiology 2023: A Summary of Key Clinical Trials

   Introduction

   Over the course of 2023, numerous key clinical trials with valuable contributions to clinical cardiology were published or presented at...

   Patrick Savage, Brian Cox, ... Ian Menown in Advances in Therapy

   Article Open access 14 May 2024
   

5. Compensation in Neonatal Clinical Trials: A Perspective

   Well conducted clinical trials are the mainstay for generating evidence on preferred treatments. In order to adequately protect the interests of the...

   Apoorva Mathur, Dilip Raja, ... Ramesh Poluru in Indian Pediatrics

   Article 19 March 2024

6. Gender inequality in genitourinary malignancies clinical trials leadership

   Background

   Over the past 2 decades, there has been a growing interest in the significance of gender roles in healthcare and several efforts and...

   Abdulrahman Alhajahjeh, Ahmed A. Abdulelah, ... Mohammed Shahait in World Journal of Urology

   Article 20 March 2024
   

7. Ethical Considerations in Decentralized Clinical Trials

   As a consequence of the COVID-19 pandemic, the number of decentralized clinical trials, trials conducted in whole or in part at locations other than...

   Barbara E. Bierer, Sarah A. White in Journal of Bioethical Inquiry

   Article 01 December 2023

8. The future of clinical trials—goals, ideas, and discussion

   Clinical trials are subject to an ever-evolving landscape of treatment options, regulatory requirements, socioeconomic conditions, and paradigms of...

   Michael Gnant, Manuela Gili, ... Hannes Fohler in memo - Magazine of European Medical Oncology

   Article Open access 18 April 2024

9. Publication Bias in Upper Gastrointestinal Oncology Clinical Trials

   Purpose

   Evidence-based medicine requires evaluation of the medical literature to guide clinical reasoning and treatment recommendations. The presence...

   Trenton Lippert, Erin Schmucker, ... Vic Velanovich in Journal of Gastrointestinal Cancer

   Article 28 March 2024
   

10. Designing acute kidney injury clinical trials

    Acute kidney injury (AKI) is a common clinical condition with various causes and is associated with increased mortality. Despite advances in...

    Alexander Zarbock, Lui G. Forni, ... John A. Kellum in Nature Reviews Nephrology

    Article 31 August 2023
    

11. Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU): Trial Satisfaction and Attitudes towards Future Clinical Trials

    Background

    Clinical trial satisfaction is increasingly important for future trial designs and is associated with treatment adherence and willingness...

    Haiyan Liu, J. Li, ... Jorge J. Llibre-Guerra in The Journal of Prevention of Alzheimer's Disease

    Article 19 March 2024
    

12. Patients Drive Authentic Trusted Solutions for Inclusive Clinical Trials

    Purpose of Review

    Cancer clinical trials remain highly underrepresented from racial and ethnic minorities. The lack of diversity in clinical trials...

    Maimah Karmo, Katherine Cornish, ... Jeanne Regnante in Current Breast Cancer Reports

    Article 03 February 2024

13. Patient communication and experiences in cancer clinical drug trials: a mixed-method study at a specialist clinical trials unit

    Background

    As cancer therapies increase in their complexity, effective communication among patients, physicians, and research staff is critical for...

    Rowan Forbes Shepherd, Ashleigh Bradford, ... Amelia Hyatt in Trials

    Article Open access 13 June 2023
    

14. Advances in Clinical Cardiology 2022: A Summary of Key Clinical Trials

    Introduction

    Over the course of 2022, numerous key clinical trials with valuable contributions to clinical cardiology were published or presented at...

    Patrick Savage, Brian Cox, ... Ian Menown in Advances in Therapy

    Article Open access 13 April 2023
    

15. Clinical Meaningfulness in Alzheimer’s Disease Clinical Trials. A Report from the EU-US CTAD Task Force

    Recent positive results of three phase III anti-amyloid monoclonal antibody trials are transforming the landscape of disease-modifying therapeutics...

    D. Angioni, J. Cummings, ... ** Zhou in The Journal of Prevention of Alzheimer's Disease

    Article 13 June 2024

16. Breast Cancer Clinical Trials in East Africa

    Purpose of Review

    Breast cancer is one of the commonest cancers among women in sub-Saharan Africa. It occurs at an earlier age and with a more...

    Karishma Sharma, Joseph Abuodha, ... Mansoor Saleh in Current Breast Cancer Reports

    Article 19 August 2023
    

17. Discontinuation and nonpublication of clinical trials in orthopaedic oncology

    Background

    Despite the pivotal role of clinical trials in advancing orthopaedic oncology knowledge and treatment strategies, the persistent issues of...

    Gurbinder Singh, Aboubacar Wague, ... Jeffrey Barry in Journal of Orthopaedic Surgery and Research

    Article Open access 05 February 2024
    

18. Utilization of EHRs for clinical trials: a systematic review

    Background and objective

    Clinical trials are of high importance for medical progress. This study conducted a systematic review to identify the...

    Leila R. Kalankesh, Elham Monaghesh in BMC Medical Research Methodology

    Article Open access 18 March 2024
    

19. Ongoing and Future Clinical Trials of Pharmacotherapy for Heart Failure

    Increasing knowledge of the processes leading to heart failure (HF) has allowed significant developments in therapies for HF over the past few...

    Taha Mansoor, Subaina N. Khalid, ... Abdul Mannan Khan Minhas in American Journal of Cardiovascular Drugs

    Article 22 June 2024
    

20. The unblinding of statisticians in clinical trials: commentary on Iflaifel et al., Trials 2023

    Recently, the Blinding of Trial Statisticians research team, Iflaifel and colleagues, have produced detailed guidance regarding the blinding or...

    Richard A. Parker in Trials

    Article Open access 11 September 2023