Search
Search Results
-
Clinical use of thyroglobulin: not only thyroid cancer
Thyroglobulin (TG) is a dimeric glycoprotein produced exclusively by mature thyroid tissue and stored within the follicular lumen. It is essential...
-
Question-answering system extracts information on injection drug use from clinical notes
BackgroundInjection drug use (IDU) can increase mortality and morbidity. Therefore, identifying IDU early and initiating harm reduction interventions...
-
Engaging people who use drugs in clinical research: integrating facilitated telemedicine for HCV into substance use treatment
BackgroundPeople who use drugs (PWUD) have difficulty participating in clinical research. We evaluated approaches to engage PWUD in clinical...
-
Chiropractors’ perceptions on the use of spinal radiographs in clinical practice: a qualitative study
BackgroundRadiography is commonly used in the assessment of spinal disorders, despite a lack of high-quality evidence demonstrating improved clinical...
-
Effectiveness and safety of primary prophylaxis of G-CSF during chemotherapy for prostate cancer, Japanese clinical guideline for appropriate use of G-CSF: clinical practice guidelines for the use of G-CSF 2022
BackgroundDocetaxel (DTX) is commonly used as a primary chemotherapy, and cabazitaxel (CBZ) has shown efficacy in patients who are DTX resistant....
-
Therapeutic use of granulocyte colony-stimulating factor (G-CSF) in patients with febrile neutropenia: a comprehensive systematic review for clinical practice guidelines for the use of G-CSF 2022 from the Japan Society of Clinical Oncology
BackgroundFebrile neutropenia represents a critical oncologic emergency, and its management is pivotal in cancer therapy. In several guidelines, the...
-
A Randomized Clinical Trial of Mobile Contingency Management Intervention for Cannabis Use Reduction
Cannabis use problems are on the rise in the USA, and there is a significant need for novel approaches to increase heavy cannabis users’ access to...
-
Advancing 6-bromo-7-[11C]methylpurine to clinical use: improved regioselective radiosynthesis, non-clinical toxicity data and human dosimetry estimates
Background6-Bromo-7-[ 11 C]methylpurine ([ 11 C]BMP) is a radiotracer for positron emission tomography (PET) to measure multidrug resistance-associated...
-
‘It depends’: what 86 systematic reviews tell us about what strategies to use to support the use of research in clinical practice
BackgroundThe gap between research findings and clinical practice is well documented and a range of strategies have been developed to support the...
-
Designing clinical trials to address alcohol use and alcohol-associated liver disease: an expert panel Consensus Statement
Most patients with alcohol-associated liver disease (ALD) engage in heavy drinking defined as 4 or more drinks per day (56 g) or 8 (112 g) or more...
-
Gene therapy: principles, challenges and use in clinical practice
IntroductionGene therapy is an emerging topic in medicine. The first products have already been licensed in the European Union for the treatment of...
-
Toward a Nanoencapsulated EPR Imaging Agent for Clinical Use
PurposeProgress toward develo** a novel radiocontrast agent for determining pO 2 in tumors in a clinical setting is described. The imaging agent is...
-
Improving routine use of clinical pathway decision support through integration of an EHR with a clinical library resource designed to provide evidence-based guidance within oncology workflows
BackgroundThe rapid evolution, complexity, and specialization of oncology treatment makes it challenging for physicians to provide care based on the...
-
Effects of cannabidiol on anandamide levels in individuals with cannabis use disorder: findings from a randomised clinical trial for the treatment of cannabis use disorder
Cannabidiol (CBD) has shown promise in treating psychiatric disorders, including cannabis use disorder – a major public health burden with no...
-
Psychotherapeutic Interventions in Clinical Trials of Psychedelics for the Treatment of Alcohol Use Disorder
Purpose of ReviewAlcohol use disorder (AUD) is the most common substance use disorder in the USA, with a considerable burden of disease. In recent...
-
Clinical trial of a low-cost external fixator for global surgery use
PurposeA low-cost modular external fixator for the lower limb has been developed for global surgery use. The purpose of this study is to assess...
-
Expert Consensus on SABA Use for Asthma Clinical Decision-Making: A Delphi Approach
Purpose of ReviewA modified Delphi process was undertaken to provide a US expert-led consensus to guide clinical action on short-acting beta 2 -agonist...
-
Tofacitinib use in ulcerative colitis: An expert consensus for day-to-day clinical practice
Rising number of inflammatory bowel disease (IBD) cases in develo** countries necessitate clear guidance for clinicians for the appropriate use of...
-
Methods for Navigating the Mobile Mental Health App Landscape for Clinical Use
There are over 10,000 mental health and wellness apps on the market. Apps offer the opportunity to increase access to mental health care. However,...
-
The use of patient reported outcome measures in oncology clinical practice across Australia and New Zealand
BackgroundWhile there is increasing evidence on the benefits of PROMs in cancer care, the extent of routine collection and use of PROMs in clinical...
